Basic Information
RNALocate ID: RLID:00015631
RNA Symbol: PTGS2
Localization: Polysome
Localization from RNA-seq Dataset:  
RNA Information
RNA Name: PTGS2
RNA ID: NCBI:5743|Ensembl:ENSG00000073756
RNA Category: mRNA
Species: Homo sapiens
Alias: COX-2|COX2|GRIPGHS|PGG/HS|PGHS-2|PHS-2|hCox-2
Sequence:
Localization Information
PubMed ID: 26000482
Tissue/Cell Line: HeLa cells
Method: qRT-PCR

Quantification of RNAs of non-polysome and polysome fractions. The lysates from HeLa cells transfected with indicated siRNA and stimulated with IL-1β were fractionated by sucrose gradient (F), and RNAs from the fractions were analyzed by RT-qPCR for the expression of indicated mRNAs (G and H).

Originally published in Cell. Mino T, et al, 2015. Reproduced under the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/)

Description: Knockdown of Reg1 resulted in a large increase in IL6 and PTGS2 mRNA expression in the polysome fractions (fractions 7-12) compared with control cells, whereas the mRNA in non-polysome fractions (fractions 3-6) were comparable (Figure 3H).
Other Subcellular Localization
RNALocate ID Localization Tissue/Cell line PubMed ID
RLID-D:00037438 Nucleus HeLa-S3 cells
RLID-D:10011743 Exosome Blood
RNA Interaction Information
Resource RNA Symbol Species Link RNALocate ID
RNAInter AFAP1-AS1 Homo sapiens RR00052448
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