Detail-Interactions: | |
RAID ID: | RRI00000027 |
---|---|
RNA/Protein Symbol 1: | KRASP1(KRAS1P) |
RNA/Protein Category 1: | lncRNA |
RNA/Protein Symbol 2: | MIRLET7B(let-7b) |
RNA/Protein Category 2: | miRNA |
Validated Method: | Dual Luciferase reporter assay, RT-PCR |
Tissue: | |
PMID: | 20577206 |
Detail description: | Further examples of such conservation include: miR-34 family binding site on CDK4PS (Supplementary Fig. 12); miR-182 binding site on FOXO3B (Supplementary Fig. 13); miR-17 family binding site on E2F3P1 (Supplementary Fig. 14); miR-143 and let-7 family binding sites on KRAS1P (Supplementary Fig. 15). |
The Predicated Binding Sites between MIRLET7B and KRASP1 | |||||
By miRanda | Structure | Match Score | Energy Score | MIRLET7B Location | KRASP1 Location |
Query: 3' uugGUGUGUUGGAUGAUGGAGu 5' ||::||::: |:|||:|| Ref: 5' gugCAUGCAGUUGAUUACUUCu 3' |
135.00 | -16.85 | 2-20 | 1029-1050 | |
Query: 3' uuGGU-GUGUUGGAUGAUGGAGu 5' ||| | :: |:||||::||| Ref: 5' cgCCAUCUUGUCUUACUGUCUCa 3' |
131.00 | -21.95 | 2-21 | 3095-3117 | |
Query: 3' uuGGUGUGUUGGAUGAUGGAGu 5' || :||| |:||:| |||| Ref: 5' ucCCUUACAUCUUAUUUCCUCa 3' |
128.00 | -20.52 | 2-21 | 2698-2719 |
The Predicated Binding Sites between MIRLET7B and KRASP1 | ||||
By RIsearch | Structure | MIRLET7B Location | KRASP1 Location | Score |
Query: 3' GGUAGUAGGUUGUGUGGUU 5' :|:||||::|: |:||||| Target: 5' UCGUCAUUUAGAAUACCAA 3' |
4-22 | 2634-2652 | -19.71 |
The Predicated Binding Sites of KRASP1 | |
RBPBD | |
RsiteDB | |
BindN | |
BindN+ | |
RNAbindR | |
Pprint |
The 'First Node' or 'Second Node' option represents the sub-network of interacting RNA/Protein with the first or second interaction node,
the 'Both the Nodes' option represents the sub-network of interacting RNA/Protein with both of interaction nodes.
The 'First Neighbour' represents the sub-network of direct interacting with the center node,
the 'Second Neighbour' represents the sub-network of direct or second step interacting with the center node.
Interaction sub-network based on the two nodes of this interaction may help the researchers represents all interacting partners immediately.
The Detail page: representing the detail information for RNA-RNA/RNA-Protein interaction;
The Binding page: representing the predicted binding sites and/or constants.
The Network page: representing the interaction sub-network of interacting RNA/Protein.