Detail-Interactions: | |
RAID ID: | RRI00000024 |
---|---|
RNA/Protein Symbol 1: | KRASP1(KRAS1P) |
RNA/Protein Category 1: | lncRNA |
RNA/Protein Symbol 2: | MIRLET7A1(let-7a-1) |
RNA/Protein Category 2: | miRNA |
Validated Method: | Dual Luciferase reporter assay, RT-PCR |
Tissue: | |
PMID: | 20577206 |
Detail description: | Further examples of such conservation include: miR-34 family binding site on CDK4PS (Supplementary Fig. 12); miR-182 binding site on FOXO3B (Supplementary Fig. 13); miR-17 family binding site on E2F3P1 (Supplementary Fig. 14); miR-143 and let-7 family binding sites on KRAS1P (Supplementary Fig. 15). |
The Predicated Binding Sites between MIRLET7A1 and KRASP1 | |||||
By miRanda | Structure | Match Score | Energy Score | MIRLET7A1 Location | KRASP1 Location |
Query: 3' uugaUAUGUUGGAUGAUGGAGu 5' ||:||::: |:|||:|| Ref: 5' gugcAUGCAGUUGAUUACUUCu 3' |
134.00 | -15.85 | 2-19 | 1029-1050 | |
Query: 3' uuGAUAUGUUGGAU-GAUGGAGu 5' || | ::|:||| ||||:|: Ref: 5' aaCUCUUUGAUCUAGCUACUUUa 3' |
131.00 | -16.19 | 2-21 | 3579-3601 | |
Query: 3' uugaUAUGUUGGAU-GAUGGAgu 5' ||::||| || :||||| Ref: 5' cuuaAUGUAACAUAUUUACCUgg 3' |
129.00 | -13.54 | 3-19 | 5041-5063 |
The Predicated Binding Sites between MIRLET7A1 and KRASP1 | ||||
By RIsearch | Structure | MIRLET7A1 Location | KRASP1 Location | Score |
Query: 3' UGAGGUAGUAGGUUGUA 5' ||||| |:||:| |||| Target: 5' ACUCCUUUAUUCUACAU 3' |
1-17 | 2703-2719 | -14.71 |
The Predicated Binding Sites of KRASP1 | |
RBPBD | |
RsiteDB | |
BindN | |
BindN+ | |
RNAbindR | |
Pprint |
The 'First Node' or 'Second Node' option represents the sub-network of interacting RNA/Protein with the first or second interaction node,
the 'Both the Nodes' option represents the sub-network of interacting RNA/Protein with both of interaction nodes.
The 'First Neighbour' represents the sub-network of direct interacting with the center node,
the 'Second Neighbour' represents the sub-network of direct or second step interacting with the center node.
Interaction sub-network based on the two nodes of this interaction may help the researchers represents all interacting partners immediately.
The Detail page: representing the detail information for RNA-RNA/RNA-Protein interaction;
The Binding page: representing the predicted binding sites and/or constants.
The Network page: representing the interaction sub-network of interacting RNA/Protein.