The Detail Information for This Interaction


  • Detail
  • Binding
  • Network
Detail-Interactions:
RAID ID: RPI00001559
RNA/Protein Symbol 1:VEGFA mRNA(VEGF-A)
RNA/Protein Category 1: mRNA
RNA/Protein Symbol 2: TIS11b/TTP
RNA/Protein Category 2: Protein
Validated Method:
Tissue:  
PMID: 23851566 
Detail description:

AU-rich elements within the VEGF-A 3¡ä-UTR also confer hypoxia-dependent mRNA stability (81¨C83). RNA-binding proteins interacting with these 3¡ä-UTR elements include the CSD/PTB complex (Cold Shock Domain/Polypyrimidine Tract Binding Protein) (84), HuR (85), hnRNP L (86), PAIP2 [Poly(A)-Binding Interacting Protein 2] (87,88), TIS11b/TTP (89) and finally, the double strand RNA-binding protein DRBP76/NF90 (90). 

The Predicated Binding Sites between and
By miRanda Structure Match Score Energy Score Location Location
The Predicated Binding Sites between and
By RIsearch Structure Location Location Score
The Predicated Binding Sites of TIS11b/TTP
RBPBD
RsiteDB
BindN
BindN+
RNAbindR
Pprint
Visualization:
Select the center nodes: First Node Second Node Both the Nodes
Select the Level of Neighbour: First Neighbour Second Neighbour

The 'First Node' or 'Second Node' option represents the sub-network of interacting RNA/Protein with the first or second interaction node, the 'Both the Nodes' option represents the sub-network of interacting RNA/Protein with both of interaction nodes.
The 'First Neighbour' represents the sub-network of direct interacting with the center node, the 'Second Neighbour' represents the sub-network of direct or second step interacting with the center node. Interaction sub-network based on the two nodes of this interaction may help the researchers represents all interacting partners immediately.


The Detail page: representing the detail information for RNA-RNA/RNA-Protein interaction;
The Binding page: representing the predicted binding sites and/or constants.
The Network page: representing the interaction sub-network of interacting RNA/Protein.