Detail

Detail-Interactions:
RAID ID:	RPI00000647
RNA/Protein Symbol 1:	FTH1 mRNA(ferritin)
RNA/Protein Category 1:	mRNA
RNA/Protein Symbol 2:	ACO1(IRP1)
RNA/Protein Category 2:	Protein
Validated Method:	Electrophoretic Mobility Shift Assay (EMSA)
Tissue:
PMID:	12855587
Detail description:	Iron regulatory proteins (IRP1 and IRP2) are RNA-binding proteins that affect the translation and stabilization of specific mRNAs by binding to stem-loop structures known as iron responsive elements (IREs). IREs are found in the 5`-untranslated region (UTR) of ferritin (Ft) and mitochondrial aconitase (m-Aco) mRNAs, and in the 3`-UTR of transferrin receptor (TfR) and divalent metal transporter-1 (DMT1) mRNAs.

Detail-Interactions:

RAID ID:

RPI00000647

RNA/Protein Symbol 1:

FTH1 mRNA(ferritin)

RNA/Protein Category 1:

mRNA

RNA/Protein Symbol 2:

ACO1(IRP1)

RNA/Protein Category 2:

Protein

Validated Method:

Electrophoretic Mobility Shift Assay (EMSA)

Tissue:

PMID:

12855587

Detail description:

Iron regulatory proteins (IRP1 and IRP2) are RNA-binding proteins that affect the translation and stabilization of specific mRNAs by binding to stem-loop structures known as iron responsive elements (IREs). IREs are found in the 5`-untranslated region (UTR) of ferritin (Ft) and mitochondrial aconitase (m-Aco) mRNAs, and in the 3`-UTR of transferrin receptor (TfR) and divalent metal transporter-1 (DMT1) mRNAs.

>sp|P21399|ACOC_HUMAN Cytoplasmic aconitate hydratase OS=Homo sapiens GN=ACO1 PE=1 SV=3 Sequence: MSNPFAHLAEPLDPVQPGKKFFNLNKLEDSRYGRLPFSIRVLLEAAIRNCDEFLVKKQDI Prediction: ------------------++-------+-+++-+-----+-------+------------ Confidence: 634789599889756234664427525435853942539599968796589677924468 Sequence: ENILHWNVTQHKNIEVPFKPARVILQDFTGVPAVVDFAAMRDAVKKLGGDPEKINPVCPA Prediction: ------------------+--+------------------+---++---+--+------- Confidence: 569988583352372746447788879937858999888754465554353367348769 Sequence: DLVIDHSIQVDFNRRADSLQKNQDLEFERNRERFEFLKWGSQAFHNMRIIPPGSGIIHQV Prediction: -------------++-++++--------+-+-+--------------------+------ Confidence: 899997684523466458552326425362646456836823643692853665568359 Sequence: NLEYLARVVFDQDGYYYPDSLVGTDSHTTMIDGLGILGWGVGGIEAEAVMLGQPISMVLP Prediction: ------+----------------+-+---------------------------------- Confidence: 596399699985662235535454262224968988785885685769978737936998 Sequence: QVIGYRLMGKPHPLVTSTDIVLTITKHLRQVGVVGKFVEFFGPGVAQLSIADRATIANMC Prediction: -----+---+-----+---------+--+------------------------------- Confidence: 587835644563247433576848253872856772897999687738257527277367 Sequence: PEYGATAAFFPVDEVSITYLVQTGRDEEKLKYIKKYLQAVGMFRDFNDPSQDPDFTQVVE Prediction: -----+---------------++-+-+++--+-+---------+---------------- Confidence: 664665676889989394265552734565246623936687858745333434745995 Sequence: LDLKTVVPCCSGPKRPQDKVAVSDMKKDFESCLGAKQGFKGFQVAPEHHNDHKTFIYDNT Prediction: ----------+++++++-+-------+--------++--+------------+------- Confidence: 978347645276799662676523524664347657533666375453235444573865 Sequence: EFTLAHGSVVIAAITSCTNTSNPSVMLGAGLLAKKAVDAGLNVMPYIKTSLSPGSGVVTY Prediction: ---------------+-+++++-+---------+-------------+-+-+--+----- Confidence: 783684838857882726675525867775656528637685965495253523725622 Sequence: YLQESGVMPYLSQLGFDVVGYGCMTCIGNSGPLPEPVVEAITQGDLVAVGVLSGNRNFEG Prediction: ----------------------------------------------------+-++++-- Confidence: 294546745393399779883756246622335558996992486787876462586423 Sequence: RVHPNTRANYLASPPLVIAYAIAGTIRIDFEKEPLGVNAKGQQVFLKDIWPTRDEIQAVE Prediction: +--++++-++--+-----------+-+----------+-+--+---------+------- Confidence: 852556947855567699948764466537627663554842587957946347652685 Sequence: RQYVIPGMFKEVYQKIETVNESWNALATPSDKLFFWNSKSTYIKSPPFFENLTLDLQPPK Prediction: ---------------------------+---+------++++-+---------------+ Confidence: 264883899258453972637544655522546585327689382366667958462245 Sequence: SIVDAYVLLNLGDSVTTDHISPAGNIARNSPAARYLTNRGLTPREFNSYGSRRGNDAVMA Prediction: ---------------+--------+--+-++-+++-++++-+-++-+++++++-+----- Confidence: 258695999687425524472362634926624974548545274466878983723659 Sequence: RGTFANIRLLNRFLNKQAPQTIHLPSGEILDVFDAAERYQQAGLPLIVLAGKEYGAGSSR Prediction: +-+----+---+---++--++----------------+-+-----------+-+++++++ Confidence: 665363857735573544254625327799999987553525576999776456656779 Sequence: DWAAKGPFLLGIKAVLAESYERIHRSNLVGMGVIPLEYLPGENADALGLTGQERYTIIIP Prediction: ++--+----------------+--+------------------------+-+-+------ Confidence: 563558657889376673325652742755788869637376375564462426248896 Sequence: ENLKPQMKVQVKLDTGKTFQAVMRFDTDVELTYFLNGGILNYMIRKMAK Prediction: ---+---+---+--+-+--+------------------------+---+ Confidence: 5565325573665363725457729826979459957788246962576 *** Prediction: binding residues are labeled with '+' and in red; non-binding residues labeled with '-' and in green. *** Confidence: from level 0 (lowest) to level 9 (highest).

>sp|P21399|ACOC_HUMAN Cytoplasmic aconitate hydratase OS=Homo sapiens GN=ACO1 PE=1 SV=3 Sequence: MSNPFAHLAEPLDPVQPGKKFFNLNKLEDSRYGRLPFSIRVLLEAAIRNCDEFLVKKQDI Prediction: -+----------------+++-+----------+-+++-+----+--+------------ Confidence: 132336289778443232543335328778345644436444924793498246825448 Sequence: ENILHWNVTQHKNIEVPFKPARVILQDFTGVPAVVDFAAMRDAVKKLGGDPEKINPVCPA Prediction: -------------------------+--+--+--------+------++--++------- Confidence: 646745542775997868356145735642535567636645341225323375237659 Sequence: DLVIDHSIQVDFNRRADSLQKNQDLEFERNRERFEFLKWGSQAFHNMRIIPPGSGIIHQV Prediction: -------------+--------------+------------------+---------+-- Confidence: 785952453614241625887989967732374567924864651673422332215523 Sequence: NLEYLARVVFDQDGYYYPDSLVGTDSHTTMIDGLGILGWGVGGIEAEAVMLGQPISMVLP Prediction: +-----------------------+++++--+----------+----------------- Confidence: 366369596788655368868362588451473511631531422236969432823457 Sequence: QVIGYRLMGKPHPLVTSTDIVLTITKHLRQVGVVGKFVEFFGPGVAQLSIADRATIANMC Prediction: -----+---------+-+----------+-------------------------+--+-- Confidence: 325385521372224434365649615852313121483644654347247217342623 Sequence: PEYGATAAFFPVDEVSITYLVQTGRDEEKLKYIKKYLQAVGMFRDFNDPSQDPDFTQVVE Prediction: -----+------------------+----------------------------------- Confidence: 513354335577666267163424643226458665978889749845687578698696 Sequence: LDLKTVVPCCSGPKRPQDKVAVSDMKKDFESCLGAKQGFKGFQVAPEHHNDHKTFIYDNT Prediction: ----------+++++++-+----------------------------------------- Confidence: 839638654653377551467623484887899996575275386562446857654867 Sequence: EFTLAHGSVVIAAITSCTNTSNPSVMLGAGLLAKKAVDAGLNVMPYIKTSLSPGSGVVTY Prediction: ---------------+++++++-----------++------+++++-----++++----- Confidence: 787772846735644646575421517356455632211114333561543464724718 Sequence: YLQESGVMPYLSQLGFDVVGYGCMTCIGNSGPLPEPVVEAITQGDLVAVGVLSGNRNFEG Prediction: -----------------------+-+-++-----------------------+++++--+ Confidence: 398698987896365977872334243451325668788975888799974268698116 Sequence: RVHPNTRANYLASPPLVIAYAIAGTIRIDFEKEPLGVNAKGQQVFLKDIWPTRDEIQAVE Prediction: +-++--+--+--+-----------+----------------+------------------ Confidence: 816811721621638227846764482557448655553123254834732238896999 Sequence: RQYVIPGMFKEVYQKIETVNESWNALATPSDKLFFWNSKSTYIKSPPFFENLTLDLQPPK Prediction: -----------------------------------------+-+---------------- Confidence: 498988787476366976656443899775655688986423543551353868777564 Sequence: SIVDAYVLLNLGDSVTTDHISPAGNIARNSPAARYLTNRGLTPREFNSYGSRRGNDAVMA Prediction: ------------------+-+---------+---------------+-++-++-+----- Confidence: 665792889399558412343242164224324225533677435532331852625249 Sequence: RGTFANIRLLNRFLNKQAPQTIHLPSGEILDVFDAAERYQQAGLPLIVLAGKEYGAGSSR Prediction: +----+--------------------------------+--------------++-++++ Confidence: 441225717613353752264438569988997866314337787898777446516758 Sequence: DWAAKGPFLLGIKAVLAESYERIHRSNLVGMGVIPLEYLPGENADALGLTGQERYTIIIP Prediction: -+-------------------+--+++--++----------------------------- Confidence: 152439334537173541123621547124356558588799798887956784879899 Sequence: ENLKPQMKVQVKLDTGKTFQAVMRFDTDVELTYFLNGGILNYMIRKMAK Prediction: -----------+----------------------------++--++--+ Confidence: 7694868795935426247686919739958946225223543746377 *** Prediction: binding residues are labeled with '+' and in red; non-binding residues labeled with '-' and in green. *** Confidence: from level 0 (lowest) to level 9 (highest).

>P21399|ACO1 Sequence: MSNPFAHLAEPLDPVQPGKKFFNLNKLEDSRYGRLPFSIRVLLEAAIRNCDEFLVKKQDI Prediction: --+----------------+-+-----------++-++-++---+---+----------- Confidence: 247332400000012124361530110021233864780861135104502321130330 Sequence: ENILHWNVTQHKNIEVPFKPARVILQDFTGVPAVVDFAAMRDAVKKLGGDPEKINPVCPA Prediction: --------------+-++++-+---+--++--------+--+---+--+--++--+---- Confidence: 141011111122125357853934171367433444235146304611523860462210 Sequence: DLVIDHSIQVDFNRRADSLQKNQDLEFERNRERFEFLKWGSQAFHNMRIIPPGSGIIHQV Prediction: -----+----++-----+----------+++-++-++++-++-----+--+--+++++-- Confidence: 124147413365144035000100032276638545888467213216147438687734 Sequence: NLEYLARVVFDQDGYYYPDSLVGTDSHTTMIDGLGILGWGVGGIEAEAVMLGQPISMVLP Prediction: +--+--+----------------++-+++--+---+--++-++------+--+------- Confidence: 634620611300000000010135648672171126038536631210160252032001 Sequence: QVIGYRLMGKPHPLVTSTDIVLTITKHLRQVGVVGKFVEFFGPGVAQLSIADRATIANMC Prediction: ---------+-++--++++--++--+--+++++++++---------------+-+--+-- Confidence: 202214124518744558712652183196569669544323410010110252533832 Sequence: PEYGATAAFFPVDEVSITYLVQTGRDEEKLKYIKKYLQAVGMFRDFNDPSQDPDFTQVVE Prediction: ++------------------+-+-+----------+---++------------------- Confidence: 553444113210000001238253613340113115142552110000000110010000 Sequence: LDLKTVVPCCSGPKRPQDKVAVSDMKKDFESCLGAKQGFKGFQVAPEHHNDHKTFIYDNT Prediction: --------+-+++++++++----------------------------------------- Confidence: 000100047368989875842343121121100011114344001000000000000201 Sequence: EFTLAHGSVVIAAITSCTNTSNPSVMLGAGLLAKKAVDAGLNVMPYIKTSLSPGSGVVTY Prediction: --------------++++++++++++--+++--++-------++++++++++++++---- Confidence: 114032131112427878888877551465642754242314557856877897874032 Sequence: YLQESGVMPYLSQLGFDVVGYGCMTCIGNSGPLPEPVVEAITQGDLVAVGVLSGNRNFEG Prediction: ------------------------++-+++-------------------+-+++++++++ Confidence: 002102001000200210143313672686430010000000000000254669999556 Sequence: RVHPNTRANYLASPPLVIAYAIAGTIRIDFEKEPLGVNAKGQQVFLKDIWPTRDEIQAVE Prediction: +-+++-+-+++-++-----++--++-----------++--------+++++-+------- Confidence: 827654745774873241266215711120123224673444233076567461100000 Sequence: RQYVIPGMFKEVYQKIETVNESWNALATPSDKLFFWNSKSTYIKSPPFFENLTLDLQPPK Prediction: -------------------------------------------+---+------------ Confidence: 000014222411200000011111000000000101000213064335103000001102 Sequence: SIVDAYVLLNLGDSVTTDHISPAGNIARNSPAARYLTNRGLTPREFNSYGSRRGNDAVMA Prediction: -------------+--++--+++++++++++++++---+---++-+++++++++++-++- Confidence: 103303010211354466438867968886885554127223764699999996974881 Sequence: RGTFANIRLLNRFLNKQAPQTIHLPSGEILDVFDAAERYQQAGLPLIVLAGKEYGAGSSR Prediction: ++++++++-+++---+++--+++--+-----------+-------------+++++++++ Confidence: 989899692565204567445561463112222243051010020011104758997999 Sequence: DWAAKGPFLLGIKAVLAESYERIHRSNLVGMGVIPLEYLPGENADALGLTGQERYTIIIP Prediction: ++++++++--+---+----+++-+++++-++----------------------------- Confidence: 897775652462345133265947776625542331211113113111043311000001 Sequence: ENLKPQMKVQVKLDTGKTFQAVMRFDTDVELTYFLNGGILNYMIRKMAK Prediction: -----+----------+------+----------+++++-+++-++--+- Confidence: 31144510121332417201010511410001348578649881893150 *** Prediction: binding residues are labeled with '+' and in red; non-binding residues labeled with '-' and in green. *** Confidence: from level 0 (lowest) to level 9 (highest).

Sequence: MSNPFAHLAEPLDPVQPGKKFFNLNKLEDSRYGRLPFSIRVLLEAAIRNCDEFLVKKQDI Prediction: --+---------------++-+--------------++-----+---+++---------- Confidence: 114221000010100010353430020010000201431111033105430222000000 Sequence: ENILHWNVTQHKNIEVPFKPARVILQDFTGVPAVVDFAAMRDAVKKLGGDPEKINPVCPA Prediction: ------+--++---+----------+-------------+----+++++++++++----- Confidence: 001002533483016120200100052210000001010330104565543553322020 Sequence: DLVIDHSIQVDFNRRADSLQKNQDLEFERNRERFEFLKWGSQAFHNMRIIPPGSGIIHQV Prediction: ----+-+------+---------------------------------+++++++++---- Confidence: 010042500121251003002001111020000001002221111113665859542200 Sequence: NLEYLARVVFDQDGYYYPDSLVGTDSHTTMIDGLGILGWGVGGIEAEAVMLGQPISMVLP Prediction: -----------------------+++++++----------+-++---------------- Confidence: 100200010000002000000003759865300001002041530000000000000000 Sequence: QVIGYRLMGKPHPLVTSTDIVLTITKHLRQVGVVGKFVEFFGPGVAQLSIADRATIANMC Prediction: -----+-+++---+++++----------+-++++++--+-------------+------- Confidence: 220008035523236639100000002152798959225100000000200250200000 Sequence: PEYGATAAFFPVDEVSITYLVQTGRDEEKLKYIKKYLQAVGMFRDFNDPSQDPDFTQVVE Prediction: ----------------------+-+----------------------------------- Confidence: 100002002000000200000360412130000102100000000200000000000000 Sequence: LDLKTVVPCCSGPKRPQDKVAVSDMKKDFESCLGAKQGFKGFQVAPEHHNDHKTFIYDNT Prediction: ----------++-++----+---------------------------------------- Confidence: 010030000049399231130010000000321222221311221112111010011012 Sequence: EFTLAHGSVVIAAITSCTNTSNPSVMLGAGLLAKKAVDAGLNVMPYIKTSLSPGSGVVTY Prediction: -----++++-+-++++++++++---+-------+--+++++++++-------+-+----- Confidence: 102325774092667998999401053200001322444555646102000241711000 Sequence: YLQESGVMPYLSQLGFDVVGYGCMTCIGNSGPLPEPVVEAITQGDLVAVGVLSGNRNFEG Prediction: ----------------------+-+++-+---+----------+++-+-+++++++++++ Confidence: 000000000000000000000072865031005132132222344615255899999999 Sequence: RVHPNTRANYLASPPLVIAYAIAGTIRIDFEKEPLGVNAKGQQVFLKDIWPTRDEIQAVE Prediction: ++++++++++--------------------+--------+------+------------- Confidence: 999998976700000000000000100021400233223310102040001300000000 Sequence: RQYVIPGMFKEVYQKIETVNESWNALATPSDKLFFWNSKSTYIKSPPFFENLTLDLQPPK Prediction: -----------------------------------------------------------+ Confidence: 000000000000000000000000000210000000001010010012202100100233 Sequence: SIVDAYVLLNLGDSVTTDHISPAGNIARNSPAARYLTNRGLTPREFNSYGSRRGNDAVMA Prediction: ---+-+---+++-+++-+------+---------+---+-+-+--+++--+++-+----- Confidence: 312305130554065314000011311200321230014240400335323543411211 Sequence: RGTFANIRLLNRFLNKQAPQTIHLPSGEILDVFDAAERYQQAGLPLIVLAGKEYGAGSSR Prediction: ---+-+------++++--+++------------------+-------------+++++++ Confidence: 122304211113454332534110000000000210200400030000000106489969 Sequence: DWAAKGPFLLGIKAVLAESYERIHRSNLVGMGVIPLEYLPGENADALGLTGQERYTIIIP Prediction: ++----------------+++++++++++++----------------------------- Confidence: 541020111211001002754644687456400010100000000000110101000000 Sequence: ENLKPQMKVQVKLDTGKTFQAVMRFDTDVELTYFLNGGILNYMIRKMAK Prediction: ----++--++---+-----+-----------------+------+---- Confidence: 0113441245022631300400000010000000201710021053002 ***Prediction: binding residues are labeled with '+' and in red; non-binding residues labeled with '-' and in green. ***Confidence: from level 0 (lowest) to level 9 (highest).

The Detail page: representing the detail information for RNA-RNA/RNA-Protein interaction;
The Binding page: representing the predicted binding sites and/or constants.
The Network page: representing the interaction sub-network of interacting RNA/Protein.

The Predicated Binding Sites between FTH1 mRNA and ACO1
By miRanda	Structure	Match Score	Energy Score	FTH1 mRNA Location	ACO1 Location

The Predicated Binding Sites between FTH1 mRNA and ACO1
By RIsearch	Structure	FTH1 mRNA Location	ACO1 Location	Score

The Predicated Binding Sites of ACO1
RBPBD
RsiteDB
BindN	>sp\|P21399\|ACOC_HUMAN Cytoplasmic aconitate hydratase OS=Homo sapiens GN=ACO1 PE=1 SV=3 Sequence: MSNPFAHLAEPLDPVQPGKKFFNLNKLEDSRYGRLPFSIRVLLEAAIRNCDEFLVKKQDI Prediction: ------------------++-------+-+++-+-----+-------+------------ Confidence: 634789599889756234664427525435853942539599968796589677924468 Sequence: ENILHWNVTQHKNIEVPFKPARVILQDFTGVPAVVDFAAMRDAVKKLGGDPEKINPVCPA Prediction: ------------------+--+------------------+---++---+--+------- Confidence: 569988583352372746447788879937858999888754465554353367348769 Sequence: DLVIDHSIQVDFNRRADSLQKNQDLEFERNRERFEFLKWGSQAFHNMRIIPPGSGIIHQV Prediction: -------------++-++++--------+-+-+--------------------+------ Confidence: 899997684523466458552326425362646456836823643692853665568359 Sequence: NLEYLARVVFDQDGYYYPDSLVGTDSHTTMIDGLGILGWGVGGIEAEAVMLGQPISMVLP Prediction: ------+----------------+-+---------------------------------- Confidence: 596399699985662235535454262224968988785885685769978737936998 Sequence: QVIGYRLMGKPHPLVTSTDIVLTITKHLRQVGVVGKFVEFFGPGVAQLSIADRATIANMC Prediction: -----+---+-----+---------+--+------------------------------- Confidence: 587835644563247433576848253872856772897999687738257527277367 Sequence: PEYGATAAFFPVDEVSITYLVQTGRDEEKLKYIKKYLQAVGMFRDFNDPSQDPDFTQVVE Prediction: -----+---------------++-+-+++--+-+---------+---------------- Confidence: 664665676889989394265552734565246623936687858745333434745995 Sequence: LDLKTVVPCCSGPKRPQDKVAVSDMKKDFESCLGAKQGFKGFQVAPEHHNDHKTFIYDNT Prediction: ----------+++++++-+-------+--------++--+------------+------- Confidence: 978347645276799662676523524664347657533666375453235444573865 Sequence: EFTLAHGSVVIAAITSCTNTSNPSVMLGAGLLAKKAVDAGLNVMPYIKTSLSPGSGVVTY Prediction: ---------------+-+++++-+---------+-------------+-+-+--+----- Confidence: 783684838857882726675525867775656528637685965495253523725622 Sequence: YLQESGVMPYLSQLGFDVVGYGCMTCIGNSGPLPEPVVEAITQGDLVAVGVLSGNRNFEG Prediction: ----------------------------------------------------+-++++-- Confidence: 294546745393399779883756246622335558996992486787876462586423 Sequence: RVHPNTRANYLASPPLVIAYAIAGTIRIDFEKEPLGVNAKGQQVFLKDIWPTRDEIQAVE Prediction: +--++++-++--+-----------+-+----------+-+--+---------+------- Confidence: 852556947855567699948764466537627663554842587957946347652685 Sequence: RQYVIPGMFKEVYQKIETVNESWNALATPSDKLFFWNSKSTYIKSPPFFENLTLDLQPPK Prediction: ---------------------------+---+------++++-+---------------+ Confidence: 264883899258453972637544655522546585327689382366667958462245 Sequence: SIVDAYVLLNLGDSVTTDHISPAGNIARNSPAARYLTNRGLTPREFNSYGSRRGNDAVMA Prediction: ---------------+--------+--+-++-+++-++++-+-++-+++++++-+----- Confidence: 258695999687425524472362634926624974548545274466878983723659 Sequence: RGTFANIRLLNRFLNKQAPQTIHLPSGEILDVFDAAERYQQAGLPLIVLAGKEYGAGSSR Prediction: +-+----+---+---++--++----------------+-+-----------+-+++++++ Confidence: 665363857735573544254625327799999987553525576999776456656779 Sequence: DWAAKGPFLLGIKAVLAESYERIHRSNLVGMGVIPLEYLPGENADALGLTGQERYTIIIP Prediction: ++--+----------------+--+------------------------+-+-+------ Confidence: 563558657889376673325652742755788869637376375564462426248896 Sequence: ENLKPQMKVQVKLDTGKTFQAVMRFDTDVELTYFLNGGILNYMIRKMAK Prediction: ---+---+---+--+-+--+------------------------+---+ Confidence: 5565325573665363725457729826979459957788246962576 * Prediction: binding residues are labeled with '+' and in red; non-binding residues labeled with '-' and in green. * Confidence: from level 0 (lowest) to level 9 (highest).
BindN+	>sp\|P21399\|ACOC_HUMAN Cytoplasmic aconitate hydratase OS=Homo sapiens GN=ACO1 PE=1 SV=3 Sequence: MSNPFAHLAEPLDPVQPGKKFFNLNKLEDSRYGRLPFSIRVLLEAAIRNCDEFLVKKQDI Prediction: -+----------------+++-+----------+-+++-+----+--+------------ Confidence: 132336289778443232543335328778345644436444924793498246825448 Sequence: ENILHWNVTQHKNIEVPFKPARVILQDFTGVPAVVDFAAMRDAVKKLGGDPEKINPVCPA Prediction: -------------------------+--+--+--------+------++--++------- Confidence: 646745542775997868356145735642535567636645341225323375237659 Sequence: DLVIDHSIQVDFNRRADSLQKNQDLEFERNRERFEFLKWGSQAFHNMRIIPPGSGIIHQV Prediction: -------------+--------------+------------------+---------+-- Confidence: 785952453614241625887989967732374567924864651673422332215523 Sequence: NLEYLARVVFDQDGYYYPDSLVGTDSHTTMIDGLGILGWGVGGIEAEAVMLGQPISMVLP Prediction: +-----------------------+++++--+----------+----------------- Confidence: 366369596788655368868362588451473511631531422236969432823457 Sequence: QVIGYRLMGKPHPLVTSTDIVLTITKHLRQVGVVGKFVEFFGPGVAQLSIADRATIANMC Prediction: -----+---------+-+----------+-------------------------+--+-- Confidence: 325385521372224434365649615852313121483644654347247217342623 Sequence: PEYGATAAFFPVDEVSITYLVQTGRDEEKLKYIKKYLQAVGMFRDFNDPSQDPDFTQVVE Prediction: -----+------------------+----------------------------------- Confidence: 513354335577666267163424643226458665978889749845687578698696 Sequence: LDLKTVVPCCSGPKRPQDKVAVSDMKKDFESCLGAKQGFKGFQVAPEHHNDHKTFIYDNT Prediction: ----------+++++++-+----------------------------------------- Confidence: 839638654653377551467623484887899996575275386562446857654867 Sequence: EFTLAHGSVVIAAITSCTNTSNPSVMLGAGLLAKKAVDAGLNVMPYIKTSLSPGSGVVTY Prediction: ---------------+++++++-----------++------+++++-----++++----- Confidence: 787772846735644646575421517356455632211114333561543464724718 Sequence: YLQESGVMPYLSQLGFDVVGYGCMTCIGNSGPLPEPVVEAITQGDLVAVGVLSGNRNFEG Prediction: -----------------------+-+-++-----------------------+++++--+ Confidence: 398698987896365977872334243451325668788975888799974268698116 Sequence: RVHPNTRANYLASPPLVIAYAIAGTIRIDFEKEPLGVNAKGQQVFLKDIWPTRDEIQAVE Prediction: +-++--+--+--+-----------+----------------+------------------ Confidence: 816811721621638227846764482557448655553123254834732238896999 Sequence: RQYVIPGMFKEVYQKIETVNESWNALATPSDKLFFWNSKSTYIKSPPFFENLTLDLQPPK Prediction: -----------------------------------------+-+---------------- Confidence: 498988787476366976656443899775655688986423543551353868777564 Sequence: SIVDAYVLLNLGDSVTTDHISPAGNIARNSPAARYLTNRGLTPREFNSYGSRRGNDAVMA Prediction: ------------------+-+---------+---------------+-++-++-+----- Confidence: 665792889399558412343242164224324225533677435532331852625249 Sequence: RGTFANIRLLNRFLNKQAPQTIHLPSGEILDVFDAAERYQQAGLPLIVLAGKEYGAGSSR Prediction: +----+--------------------------------+--------------++-++++ Confidence: 441225717613353752264438569988997866314337787898777446516758 Sequence: DWAAKGPFLLGIKAVLAESYERIHRSNLVGMGVIPLEYLPGENADALGLTGQERYTIIIP Prediction: -+-------------------+--+++--++----------------------------- Confidence: 152439334537173541123621547124356558588799798887956784879899 Sequence: ENLKPQMKVQVKLDTGKTFQAVMRFDTDVELTYFLNGGILNYMIRKMAK Prediction: -----------+----------------------------++--++--+ Confidence: 7694868795935426247686919739958946225223543746377 * Prediction: binding residues are labeled with '+' and in red; non-binding residues labeled with '-' and in green. * Confidence: from level 0 (lowest) to level 9 (highest).
RNAbindR	>P21399\|ACO1 Sequence: MSNPFAHLAEPLDPVQPGKKFFNLNKLEDSRYGRLPFSIRVLLEAAIRNCDEFLVKKQDI Prediction: --+----------------+-+-----------++-++-++---+---+----------- Confidence: 247332400000012124361530110021233864780861135104502321130330 Sequence: ENILHWNVTQHKNIEVPFKPARVILQDFTGVPAVVDFAAMRDAVKKLGGDPEKINPVCPA Prediction: --------------+-++++-+---+--++--------+--+---+--+--++--+---- Confidence: 141011111122125357853934171367433444235146304611523860462210 Sequence: DLVIDHSIQVDFNRRADSLQKNQDLEFERNRERFEFLKWGSQAFHNMRIIPPGSGIIHQV Prediction: -----+----++-----+----------+++-++-++++-++-----+--+--+++++-- Confidence: 124147413365144035000100032276638545888467213216147438687734 Sequence: NLEYLARVVFDQDGYYYPDSLVGTDSHTTMIDGLGILGWGVGGIEAEAVMLGQPISMVLP Prediction: +--+--+----------------++-+++--+---+--++-++------+--+------- Confidence: 634620611300000000010135648672171126038536631210160252032001 Sequence: QVIGYRLMGKPHPLVTSTDIVLTITKHLRQVGVVGKFVEFFGPGVAQLSIADRATIANMC Prediction: ---------+-++--++++--++--+--+++++++++---------------+-+--+-- Confidence: 202214124518744558712652183196569669544323410010110252533832 Sequence: PEYGATAAFFPVDEVSITYLVQTGRDEEKLKYIKKYLQAVGMFRDFNDPSQDPDFTQVVE Prediction: ++------------------+-+-+----------+---++------------------- Confidence: 553444113210000001238253613340113115142552110000000110010000 Sequence: LDLKTVVPCCSGPKRPQDKVAVSDMKKDFESCLGAKQGFKGFQVAPEHHNDHKTFIYDNT Prediction: --------+-+++++++++----------------------------------------- Confidence: 000100047368989875842343121121100011114344001000000000000201 Sequence: EFTLAHGSVVIAAITSCTNTSNPSVMLGAGLLAKKAVDAGLNVMPYIKTSLSPGSGVVTY Prediction: --------------++++++++++++--+++--++-------++++++++++++++---- Confidence: 114032131112427878888877551465642754242314557856877897874032 Sequence: YLQESGVMPYLSQLGFDVVGYGCMTCIGNSGPLPEPVVEAITQGDLVAVGVLSGNRNFEG Prediction: ------------------------++-+++-------------------+-+++++++++ Confidence: 002102001000200210143313672686430010000000000000254669999556 Sequence: RVHPNTRANYLASPPLVIAYAIAGTIRIDFEKEPLGVNAKGQQVFLKDIWPTRDEIQAVE Prediction: +-+++-+-+++-++-----++--++-----------++--------+++++-+------- Confidence: 827654745774873241266215711120123224673444233076567461100000 Sequence: RQYVIPGMFKEVYQKIETVNESWNALATPSDKLFFWNSKSTYIKSPPFFENLTLDLQPPK Prediction: -------------------------------------------+---+------------ Confidence: 000014222411200000011111000000000101000213064335103000001102 Sequence: SIVDAYVLLNLGDSVTTDHISPAGNIARNSPAARYLTNRGLTPREFNSYGSRRGNDAVMA Prediction: -------------+--++--+++++++++++++++---+---++-+++++++++++-++- Confidence: 103303010211354466438867968886885554127223764699999996974881 Sequence: RGTFANIRLLNRFLNKQAPQTIHLPSGEILDVFDAAERYQQAGLPLIVLAGKEYGAGSSR Prediction: ++++++++-+++---+++--+++--+-----------+-------------+++++++++ Confidence: 989899692565204567445561463112222243051010020011104758997999 Sequence: DWAAKGPFLLGIKAVLAESYERIHRSNLVGMGVIPLEYLPGENADALGLTGQERYTIIIP Prediction: ++++++++--+---+----+++-+++++-++----------------------------- Confidence: 897775652462345133265947776625542331211113113111043311000001 Sequence: ENLKPQMKVQVKLDTGKTFQAVMRFDTDVELTYFLNGGILNYMIRKMAK Prediction: -----+----------+------+----------+++++-+++-++--+- Confidence: 31144510121332417201010511410001348578649881893150 * Prediction: binding residues are labeled with '+' and in red; non-binding residues labeled with '-' and in green. * Confidence: from level 0 (lowest) to level 9 (highest).
Pprint	Sequence: MSNPFAHLAEPLDPVQPGKKFFNLNKLEDSRYGRLPFSIRVLLEAAIRNCDEFLVKKQDI Prediction: --+---------------++-+--------------++-----+---+++---------- Confidence: 114221000010100010353430020010000201431111033105430222000000 Sequence: ENILHWNVTQHKNIEVPFKPARVILQDFTGVPAVVDFAAMRDAVKKLGGDPEKINPVCPA Prediction: ------+--++---+----------+-------------+----+++++++++++----- Confidence: 001002533483016120200100052210000001010330104565543553322020 Sequence: DLVIDHSIQVDFNRRADSLQKNQDLEFERNRERFEFLKWGSQAFHNMRIIPPGSGIIHQV Prediction: ----+-+------+---------------------------------+++++++++---- Confidence: 010042500121251003002001111020000001002221111113665859542200 Sequence: NLEYLARVVFDQDGYYYPDSLVGTDSHTTMIDGLGILGWGVGGIEAEAVMLGQPISMVLP Prediction: -----------------------+++++++----------+-++---------------- Confidence: 100200010000002000000003759865300001002041530000000000000000 Sequence: QVIGYRLMGKPHPLVTSTDIVLTITKHLRQVGVVGKFVEFFGPGVAQLSIADRATIANMC Prediction: -----+-+++---+++++----------+-++++++--+-------------+------- Confidence: 220008035523236639100000002152798959225100000000200250200000 Sequence: PEYGATAAFFPVDEVSITYLVQTGRDEEKLKYIKKYLQAVGMFRDFNDPSQDPDFTQVVE Prediction: ----------------------+-+----------------------------------- Confidence: 100002002000000200000360412130000102100000000200000000000000 Sequence: LDLKTVVPCCSGPKRPQDKVAVSDMKKDFESCLGAKQGFKGFQVAPEHHNDHKTFIYDNT Prediction: ----------++-++----+---------------------------------------- Confidence: 010030000049399231130010000000321222221311221112111010011012 Sequence: EFTLAHGSVVIAAITSCTNTSNPSVMLGAGLLAKKAVDAGLNVMPYIKTSLSPGSGVVTY Prediction: -----++++-+-++++++++++---+-------+--+++++++++-------+-+----- Confidence: 102325774092667998999401053200001322444555646102000241711000 Sequence: YLQESGVMPYLSQLGFDVVGYGCMTCIGNSGPLPEPVVEAITQGDLVAVGVLSGNRNFEG Prediction: ----------------------+-+++-+---+----------+++-+-+++++++++++ Confidence: 000000000000000000000072865031005132132222344615255899999999 Sequence: RVHPNTRANYLASPPLVIAYAIAGTIRIDFEKEPLGVNAKGQQVFLKDIWPTRDEIQAVE Prediction: ++++++++++--------------------+--------+------+------------- Confidence: 999998976700000000000000100021400233223310102040001300000000 Sequence: RQYVIPGMFKEVYQKIETVNESWNALATPSDKLFFWNSKSTYIKSPPFFENLTLDLQPPK Prediction: -----------------------------------------------------------+ Confidence: 000000000000000000000000000210000000001010010012202100100233 Sequence: SIVDAYVLLNLGDSVTTDHISPAGNIARNSPAARYLTNRGLTPREFNSYGSRRGNDAVMA Prediction: ---+-+---+++-+++-+------+---------+---+-+-+--+++--+++-+----- Confidence: 312305130554065314000011311200321230014240400335323543411211 Sequence: RGTFANIRLLNRFLNKQAPQTIHLPSGEILDVFDAAERYQQAGLPLIVLAGKEYGAGSSR Prediction: ---+-+------++++--+++------------------+-------------+++++++ Confidence: 122304211113454332534110000000000210200400030000000106489969 Sequence: DWAAKGPFLLGIKAVLAESYERIHRSNLVGMGVIPLEYLPGENADALGLTGQERYTIIIP Prediction: ++----------------+++++++++++++----------------------------- Confidence: 541020111211001002754644687456400010100000000000110101000000 Sequence: ENLKPQMKVQVKLDTGKTFQAVMRFDTDVELTYFLNGGILNYMIRKMAK Prediction: ----++--++---+-----+-----------------+------+---- Confidence: 0113441245022631300400000010000000201710021053002 *Prediction: binding residues are labeled with '+' and in red; non-binding residues labeled with '-' and in green. *Confidence: from level 0 (lowest) to level 9 (highest).

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