The Detail Information for This Interaction


  • Detail
  • Binding
  • Network
Detail:
ncRNA Symmbol:miR-125b
ncRNA Category:miRNA
Interaction Gene Symbol:
Death Pathway:apoptosis
Expression Direction of ncRNA:
Species:Homo sapiens
Tissue:lung cancer cell
PMID: 25573191
Detail Description:

In addition, inhibition of the expression of miR?125b in 95D cells induced apoptosis, G1/Sphase arrest and reduction of their invasive ability. In addition, bioinformatics software predicted that miR?125b was involved in the regulation of several pathways associated with cancer, including the transforming growth factor?¦Â, Wnt and mitogen?activated protein kinase signaling pathways. These data indicated for the first time, to the best of our knowledge, that miR?125b may function as an oncogene in lung cancer. 

Select the ncRNA symbol and transcript of gene
Mature of miR-125b    Transcript of    
Visualization:
Select the center nodes: First Node Second Node Both the Nodes
Select the Level of Neighbour: First Neighbour Second Neighbour

The 'First Node' or 'Second Node' option represents the sub-network of interacting entry with the first or second interaction node, the 'Both the Nodes' option represents the sub-network of interacting entry with both of interaction nodes.
The 'First Neighbour' represents the sub-network of direct interacting with the center node, the 'Second Neighbour' represents the sub-network of direct or second step interacting with the center node. Interaction sub-network based on the two nodes of this interaction may help the researchers represents all interacting partners immediately.


The Detail page: representing the detail information for RNA-RNA/RNA-Protein interaction;
The Binding page: representing the predicted binding sites and/or constants.
The Network page: representing the interaction sub-network of interacting RNA/Protein.