| Gene ontology terms enriched for interacted genes |
| GO terms | GO terms description | target genes enrich in GO term | p-value |
|
|
GO:0042981
|
regulation of apoptosis |
CSTB,PRDX2,RPS3A,CDKN2A,PRKRA,XIAP,CDKN1A,IGF2,CEBPG,BBC3,VDR,BAK1,BCL3,ALDH1A3,HSPA1B,ERBB2,GRIN2A,IL6R,BCL2,ERBB3,BCL2L2,EPHA7,NPM1,HOXA13,ABL1,SORT1,AKT1,TP53,BMF,PMAIP1,MCL1,HSPD1,SMO,TP53INP1,NME2,TNFAIP3,ETS1,HTT,BCL2L13, |
2.30E-7 |
|
GO:0043067
|
regulation of programmed cell death |
CSTB,PRDX2,RPS3A,CDKN2A,PRKRA,XIAP,CDKN1A,IGF2,CEBPG,BBC3,VDR,BAK1,BCL3,ALDH1A3,HSPA1B,ERBB2,GRIN2A,IL6R,BCL2,ERBB3,BCL2L2,EPHA7,NPM1,HOXA13,ABL1,SORT1,AKT1,TP53,BMF,PMAIP1,MCL1,HSPD1,SMO,TP53INP1,NME2,TNFAIP3,ETS1,HTT,BCL2L13, |
2.96E-7 |
|
GO:0010941
|
regulation of cell death |
CSTB,PRDX2,RPS3A,CDKN2A,PRKRA,XIAP,CDKN1A,IGF2,CEBPG,BBC3,VDR,BAK1,BCL3,ALDH1A3,HSPA1B,ERBB2,GRIN2A,IL6R,BCL2,ERBB3,BCL2L2,EPHA7,NPM1,HOXA13,ABL1,SORT1,AKT1,TP53,BMF,PMAIP1,MCL1,HSPD1,SMO,TP53INP1,NME2,TNFAIP3,ETS1,HTT,BCL2L13, |
3.24E-7 |
|
GO:0006357
|
regulation of transcription from RNA polymerase II promoter |
THRAP3,IRF4,BCOR,CBFB,STAT3,MAPK14,MTF1,SP7,CEBPA,HNF4G,SUPT6H,SPEN,HNF4A,CRTC1,CEBPG,VDR,MTA2,CREBBP,CSRNP2,RYBP,ZMYND11,BCL3,PRDM1,STRN3,GLI1,ATXN1,HOXA13,ABL1,TP53,EHMT1,MED1,KLF13,LIF,SMARCD2,ETS1,TEF, |
4.74E-7 |
|
GO:0051252
|
regulation of RNA metabolic process |
THRAP3,STAT3,BACH1,YEATS2,MTF1,ZNF212,LIN28B,ASH2L,CEBPA,IGF2,SUPT6H,CRTC1,CEBPG,CREBBP,ARID3A,ESRP2,BCL3,PRDM1,ZNF395,ATXN1,HOXA13,ZNF667,ABL1,EHMT1,KLF13,NME2,SMARCD2,ETS1,LBX2,PABPC1,IRF4,BCOR,CBFB,MAPK14,SP7,CDKN2A,HMGA2,LIN28A,HNF4G,SPEN,HNF4A,E2F7,MTA2,VDR,CSRNP2,POU5F1,RYBP,CARHSP1,ZMYND11,GLI1,STRN3,NPM1,HMGA1,E2F3,TP53,E2F2,MED1,MLL2,LIF,HKR1,CCNE1,ZNF483,TEF, |
2.99E-6 |
|
|
|
GO:0043065
|
positive regulation of apoptosis |
ALDH1A3,GRIN2A,BCL2,EPHA7,HOXA13,CDKN2A,RPS3A,ABL1,PRKRA,SORT1,CDKN1A,AKT1,TP53,PMAIP1,HSPD1,TP53INP1,CEBPG,BBC3,VDR,ETS1,BAK1,HTT,BCL3,BCL2L13, |
9.43E-6 |
|
GO:0045944
|
positive regulation of transcription from RNA polymerase II promoter |
THRAP3,IRF4,GLI1,STRN3,CBFB,STAT3,MAPK14,MTF1,ATXN1,HOXA13,TP53,MED1,KLF13,CEBPA,HNF4A,CRTC1,LIF,MTA2,CSRNP2,CREBBP,ETS1,BCL3, |
9.94E-6 |
|
GO:0043068
|
positive regulation of programmed cell death |
ALDH1A3,GRIN2A,BCL2,EPHA7,HOXA13,CDKN2A,RPS3A,ABL1,PRKRA,SORT1,CDKN1A,AKT1,TP53,PMAIP1,HSPD1,TP53INP1,CEBPG,BBC3,VDR,ETS1,BAK1,HTT,BCL3,BCL2L13, |
1.06E-5 |
|
GO:0010942
|
positive regulation of cell death |
ALDH1A3,GRIN2A,BCL2,EPHA7,HOXA13,CDKN2A,RPS3A,ABL1,PRKRA,SORT1,CDKN1A,AKT1,TP53,PMAIP1,HSPD1,TP53INP1,CEBPG,BBC3,VDR,ETS1,BAK1,HTT,BCL3,BCL2L13, |
1.14E-5 |
|
GO:0006355
|
regulation of transcription, DNA-dependent |
THRAP3,STAT3,BACH1,YEATS2,MTF1,ZNF212,LIN28B,ASH2L,CEBPA,IGF2,SUPT6H,CRTC1,CEBPG,CREBBP,ARID3A,BCL3,PRDM1,ZNF395,ATXN1,HOXA13,ZNF667,ABL1,EHMT1,KLF13,NME2,SMARCD2,ETS1,LBX2,IRF4,BCOR,CBFB,MAPK14,SP7,CDKN2A,HMGA2,LIN28A,HNF4G,SPEN,HNF4A,E2F7,MTA2,VDR,CSRNP2,POU5F1,RYBP,CARHSP1,ZMYND11,GLI1,STRN3,HMGA1,E2F3,TP53,E2F2,MED1,MLL2,LIF,HKR1,CCNE1,ZNF483,TEF, |
1.30E-5 |
|
GO:0010608
|
posttranscriptional regulation of gene expression |
BCL2,CASC3,CDKN2A,LIN28B,PRKRA,KRT7,AKT1,LIN28A,HSPD1,EIF5,MKNK2,EIF4EBP1,ETF1,TNRC6B,PABPC1,BCL3, |
1.40E-5 |
|
GO:0045893
|
positive regulation of transcription, DNA-dependent |
THRAP3,IRF4,CBFB,STAT3,MTF1,MAPK14,CEBPA,HNF4A,CRTC1,MTA2,CREBBP,CSRNP2,BCL3,GLI1,STRN3,ATXN1,HOXA13,HMGA1,TP53,E2F3,MED1,KLF13,LIF,ETS1,CCNE1, |
1.66E-5 |
|
GO:0051254
|
positive regulation of RNA metabolic process |
THRAP3,IRF4,CBFB,STAT3,MTF1,MAPK14,CEBPA,HNF4A,CRTC1,MTA2,CREBBP,CSRNP2,BCL3,GLI1,STRN3,ATXN1,HOXA13,HMGA1,TP53,E2F3,MED1,KLF13,LIF,ETS1,CCNE1, |
1.91E-5 |
|
GO:0008637
|
apoptotic mitochondrial changes |
BCL2,BBC3,CDKN2A,BAK1,AKT1,TP53,PMAIP1, |
2.33E-5 |
|
GO:0051173
|
positive regulation of nitrogen compound metabolic process |
THRAP3,IRF4,CBFB,STAT3,MAPK14,MTF1,CEBPA,IGF2,HNF4A,CEBPG,CRTC1,MTA2,CREBBP,CSRNP2,USP22,BCL3,STRN3,GLI1,ATXN1,HOXA13,HMGA1,AKT1,E2F3,TP53,MED1,KLF13,LIF,ETS1,CCNE1, |
4.68E-5 |
|
GO:0008219
|
cell death |
RAF1,CDKN2A,VDAC1,XIAP,IGF2,BBC3,CSRNP2,RYBP,SGPL1,BAK1,FUS,ERBB3,BCL2,BCL2L2,ATXN1,NDOR1,AKT1,FXR1,TP53,E2F2,BMF,MCL1,HSPD1,LUC7L3,PMAIP1,TP53INP1,TARDBP,TNFAIP3,PKM2,HTT,BCL2L13, |
5.23E-5 |
|
GO:0010628
|
positive regulation of gene expression |
THRAP3,IRF4,CBFB,STAT3,MAPK14,MTF1,CEBPA,HNF4A,CRTC1,MTA2,CREBBP,CSRNP2,USP22,BCL3,PRDM1,STRN3,GLI1,ATXN1,HOXA13,HMGA1,TP53,E2F3,MED1,KLF13,LIF,ETS1,CCNE1, |
5.48E-5 |
|
GO:0031328
|
positive regulation of cellular biosynthetic process |
THRAP3,IRF4,CBFB,STAT3,MAPK14,MTF1,CEBPA,IGF2,HNF4A,CEBPG,CRTC1,MTA2,CREBBP,CSRNP2,USP22,BCL3,STRN3,GLI1,NPM1,ATXN1,HOXA13,HMGA1,AKT1,E2F3,TP53,MED1,KLF13,LIF,ETS1,CCNE1, |
5.49E-5 |
|
GO:0043066
|
negative regulation of apoptosis |
HSPA1B,ERBB2,ERBB3,BCL2,BCL2L2,NPM1,PRDX2,XIAP,SORT1,CDKN1A,AKT1,TP53,HSPD1,MCL1,IGF2,SMO,NME2,TNFAIP3,HTT,BCL3, |
5.52E-5 |
|
GO:0016265
|
death |
RAF1,CDKN2A,VDAC1,XIAP,IGF2,BBC3,CSRNP2,RYBP,SGPL1,BAK1,FUS,ERBB3,BCL2,BCL2L2,ATXN1,NDOR1,AKT1,FXR1,TP53,E2F2,BMF,MCL1,HSPD1,LUC7L3,PMAIP1,TP53INP1,TARDBP,TNFAIP3,PKM2,HTT,BCL2L13, |
5.89E-5 |
|
GO:0010557
|
positive regulation of macromolecule biosynthetic process |
THRAP3,IRF4,CBFB,STAT3,MAPK14,MTF1,CEBPA,IGF2,HNF4A,CEBPG,CRTC1,MTA2,CREBBP,CSRNP2,USP22,BCL3,STRN3,GLI1,ATXN1,HOXA13,HMGA1,AKT1,E2F3,TP53,MED1,KLF13,LIF,ETS1,CCNE1, |
6.12E-5 |
|
GO:0043069
|
negative regulation of programmed cell death |
HSPA1B,ERBB2,ERBB3,BCL2,BCL2L2,NPM1,PRDX2,XIAP,SORT1,CDKN1A,AKT1,TP53,HSPD1,MCL1,IGF2,SMO,NME2,TNFAIP3,HTT,BCL3, |
6.63E-5 |
|
GO:0060548
|
negative regulation of cell death |
HSPA1B,ERBB2,ERBB3,BCL2,BCL2L2,NPM1,PRDX2,XIAP,SORT1,CDKN1A,AKT1,TP53,HSPD1,MCL1,IGF2,SMO,NME2,TNFAIP3,HTT,BCL3, |
6.94E-5 |
|
GO:0045935
|
positive regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process |
THRAP3,IRF4,CBFB,STAT3,MAPK14,MTF1,CEBPA,IGF2,HNF4A,CEBPG,CRTC1,MTA2,CREBBP,CSRNP2,USP22,BCL3,STRN3,GLI1,ATXN1,HOXA13,HMGA1,E2F3,TP53,MED1,KLF13,LIF,ETS1,CCNE1, |
6.95E-5 |
|
GO:0009891
|
positive regulation of biosynthetic process |
THRAP3,IRF4,CBFB,STAT3,MAPK14,MTF1,CEBPA,IGF2,HNF4A,CEBPG,CRTC1,MTA2,CREBBP,CSRNP2,USP22,BCL3,STRN3,GLI1,NPM1,ATXN1,HOXA13,HMGA1,AKT1,E2F3,TP53,MED1,KLF13,LIF,ETS1,CCNE1, |
7.10E-5 |
|
GO:0007005
|
mitochondrion organization |
CEBPA,NDUFS7,TIMM23,BCL2,BBC3,CDKN2A,BAK1,AKT1,TIMM10,TP53,HTT,PMAIP1, |
7.14E-5 |
|
GO:0045941
|
positive regulation of transcription |
THRAP3,IRF4,CBFB,STAT3,MAPK14,MTF1,CEBPA,HNF4A,CRTC1,MTA2,CREBBP,CSRNP2,USP22,BCL3,GLI1,STRN3,ATXN1,HOXA13,HMGA1,TP53,E2F3,MED1,KLF13,LIF,ETS1,CCNE1, |
8.96E-5 |
|
GO:0010604
|
positive regulation of macromolecule metabolic process |
THRAP3,IRF4,CBFB,STAT3,MAPK14,MTF1,NRD1,CEBPA,IGF2,HNF4A,CRTC1,CEBPG,MTA2,CREBBP,CSRNP2,USP22,BCL3,IL6R,PRDM1,STRN3,GLI1,BCL2,ATXN1,HOXA13,HMGA1,AKT1,E2F3,TP53,MED1,KLF13,PSMB1,LIF,ETS1,CCNE1, |
1.04E-4 |
|
GO:0010033
|
response to organic substance |
ADM,STAT3,SIK2,MAPK14,PRDX2,ZFP106,LIN28B,PRKRA,CDKN1A,LIN28A,EDEM1,IGF2,HNF4A,EIF4EBP1,HSPA1B,ERBB2,GRIN2A,IL6R,STRN3,ERBB3,BCL2,SORT1,AKT1,MCL1,HSPD1,PMAIP1,NME2,CCNE1,MMP13,PARP1, |
1.34E-4 |
|
GO:0043434
|
response to peptide hormone stimulus |
IL6R,IGF2,BCL2,ERBB3,ADM,SIK2,STAT3,ZFP106,EIF4EBP1,SORT1,AKT1,PARP1, |
1.90E-4 |
|
GO:0006401
|
RNA catabolic process |
HSPA1B,CASC3,RNASEH2A,LIN28B,RNH1,PABPC4,SMG1,LIN28A, |
2.40E-4 |
|
GO:0052547
|
regulation of peptidase activity |
CSTB,BBC3,CDKN2A,BAK1,NRD1,TP53,BCL2L13,HSPD1,PMAIP1, |
2.43E-4 |
|
GO:0012501
|
programmed cell death |
RAF1,CDKN2A,VDAC1,XIAP,BBC3,CSRNP2,RYBP,SGPL1,BAK1,ERBB3,BCL2,BCL2L2,AKT1,FXR1,TP53,E2F2,MCL1,LUC7L3,HSPD1,PMAIP1,BMF,TP53INP1,TNFAIP3,PKM2,BCL2L13,HTT, |
3.06E-4 |
|
GO:0007169
|
transmembrane receptor protein tyrosine kinase signaling pathway |
ERBB2,ERBB3,STAT3,SIK2,EPHA7,RAF1,FGFR2,ZFP106,SORT1,AKT1,IGF2,EIF4EBP1,SGPL1,NTRK3, |
3.99E-4 |
|
GO:0006917
|
induction of apoptosis |
CDKN2A,RPS3A,ABL1,PRKRA,CDKN1A,SORT1,TP53,PMAIP1,TP53INP1,BBC3,CEBPG,VDR,ETS1,BAK1,BCL3,BCL2L13,HTT, |
4.70E-4 |
|
GO:0012502
|
induction of programmed cell death |
CDKN2A,RPS3A,ABL1,PRKRA,CDKN1A,SORT1,TP53,PMAIP1,TP53INP1,BBC3,CEBPG,VDR,ETS1,BAK1,BCL3,BCL2L13,HTT, |
4.86E-4 |
|
GO:0006351
|
transcription, DNA-dependent |
THRAP3,CBFB,CDKN2A,ASH2L,TP53,E2F3,E2F2,MED1,KLF13,CEBPA,HNF4G,TARDBP,MYEF2,ETS1,ADRM1,PARP1, |
5.33E-4 |
|
GO:0006919
|
activation of caspase activity |
BBC3,CDKN2A,BAK1,TP53,BCL2L13,HSPD1,PMAIP1, |
5.67E-4 |
|
GO:0006915
|
apoptosis |
RAF1,CDKN2A,VDAC1,XIAP,BBC3,CSRNP2,RYBP,SGPL1,BAK1,ERBB3,BCL2,BCL2L2,AKT1,FXR1,TP53,MCL1,LUC7L3,HSPD1,PMAIP1,BMF,E2F2,TP53INP1,TNFAIP3,BCL2L13,HTT, |
5.88E-4 |
|
GO:0006366
|
transcription from RNA polymerase II promoter |
THRAP3,CBFB,ASH2L,E2F3,E2F2,MED1,CEBPA,KLF13,HNF4G,TARDBP,MYEF2,ETS1,ADRM1,PARP1, |
6.03E-4 |
|
GO:0001836
|
release of cytochrome c from mitochondria |
BCL2,BBC3,BAK1,TP53,PMAIP1, |
6.16E-4 |
|
GO:0032774
|
RNA biosynthetic process |
THRAP3,CBFB,CDKN2A,ASH2L,TP53,E2F3,E2F2,MED1,KLF13,CEBPA,HNF4G,TARDBP,MYEF2,ETS1,ADRM1,PARP1, |
6.20E-4 |
|
GO:0032868
|
response to insulin stimulus |
IGF2,ERBB3,ADM,SIK2,ZFP106,EIF4EBP1,SORT1,AKT1,PARP1, |
6.77E-4 |
|
GO:0006414
|
translational elongation |
RPS7,RPL3,RPS3A,RPS12,EEF1A1,RPL35A,RPL29,RPLP0,RPS28, |
7.23E-4 |
|
GO:0051098
|
regulation of binding |
IRF4,HNF4A,BCL2,SMO,CEBPG,PRDX2,NPM1,NME2,CDKN2A,BAK1,BCL3, |
7.47E-4 |
|
GO:0006396
|
RNA processing |
SRRM2,SNRPB,KHSRP,CASC3,ATXN1,CDKN2A,LIN28B,PABPC4,PCBP2,RPL35A,PRKRA,NSUN2,LIN28A,LUC7L3,RPS28,RPS7,TARDBP,SUGP2,ESRP2,HNRNPK,DHX38,FUS,PABPC1, |
8.84E-4 |
|
GO:0010605
|
negative regulation of macromolecule metabolic process |
BCOR,STAT3,CDKN2A,LIN28B,PRKRA,LIN28A,CEBPA,SPEN,IGF2,HNF4A,VDR,MTA2,RYBP,EIF4EBP1,BAK1,TNRC6B,ZMYND11,BCL3,IL6R,GRIN2A,PRDM1,STRN3,NPM1,ATXN1,TP53,MSH3,EHMT1,PSMB1, |
9.03E-4 |
|
GO:0010952
|
positive regulation of peptidase activity |
BBC3,CDKN2A,BAK1,TP53,BCL2L13,HSPD1,PMAIP1, |
9.13E-4 |
|
GO:0043280
|
positive regulation of caspase activity |
BBC3,CDKN2A,BAK1,TP53,BCL2L13,HSPD1,PMAIP1, |
9.13E-4 |
|
GO:0002520
|
immune system development |
IRF4,BCL2,CBFB,PRDX2,ASH2L,TP53,HSPD1,MED1,MSH3,CEBPA,CEBPG,UNG,SGPL1,BAK1,BCL3, |
9.22E-4 |
|
GO:0052548
|
regulation of endopeptidase activity |
BBC3,CDKN2A,BAK1,NRD1,TP53,BCL2L13,HSPD1,PMAIP1, |
9.95E-4 |
|
GO:0046902
|
regulation of mitochondrial membrane permeability |
BCL2,BAK1,TP53,HTT, |
1.03E-2 |
|
GO:0001649
|
osteoblast differentiation |
IGF2,CYP24A1,GLI1,SMO,CBFB,SP7, |
1.20E-2 |
|
GO:0001501
|
skeletal system development |
BCL2,BMPR1B,GLI1,CBFB,MAPK14,SP7,HOXA13,PRKRA,SORT1,CYP24A1,IGF2,SMO,VDR,SGPL1,MMP13,FBN1, |
1.28E-2 |
|
GO:0016310
|
phosphorylation |
SIK2,MAPK14,RAF1,IP6K1,PRDX2,ULK3,ND6,PRKRA,BCKDK,NDUFS7,MKNK2,HK2,ATP5B,ERBB2,ERBB3,BCL2,BMPR1B,EPHA7,FGFR2,ABL1,AKT1,WNK1,AURKB,PRKAG1,NME2,SMG1,MAP3K2,RPS6KA1,NTRK3, |
1.57E-2 |
|
GO:0045597
|
positive regulation of cell differentiation |
IL6R,BCL2,BMPR1B,MAPK14,NPTN,AKT1,IGF2,SMO,LIF,NME2,ETS1,CCNE1,NTRK3, |
1.60E-2 |
|
GO:0001503
|
ossification |
IGF2,CYP24A1,GLI1,BCL2,SMO,CBFB,SP7,SORT1,MMP13, |
1.68E-2 |
|
GO:0009314
|
response to radiation |
IL6R,GRIN2A,BCL2,ATXN1,CNGB1,CDKN1A,BAK1,AKT1,TP53,HTT,BCL3,NES, |
1.70E-2 |
|
GO:0051726
|
regulation of cell cycle |
MAD1L1,BCL2,MAPK14,NPM1,HOXA13,CDKN2A,CDKN1A,AKT1,TP53,E2F2,IGF2,HNF4A,LIF,USP22,ETS1,BAK1, |
1.88E-2 |
|
GO:0006412
|
translation |
MTRF1L,RPL3,RPS3A,EEF1A1,RPS12,PABPC4,EIF1AX,RPL35A,RPL29,RPLP0,RPS28,EIF5,RPS7,HBS1L,ABTB1,ETF1, |
1.88E-2 |
|
GO:0032869
|
cellular response to insulin stimulus |
IGF2,ERBB3,SIK2,ZFP106,EIF4EBP1,AKT1,PARP1, |
1.92E-2 |
|
GO:0006796
|
phosphate metabolic process |
SIK2,MAPK14,RAF1,IP6K1,PRDX2,ULK3,ND6,PRKRA,BCKDK,NDUFS7,MKNK2,MTMR3,HK2,ATP5B,ERBB2,ERBB3,BCL2,BMPR1B,EPHA7,MTMR12,FGFR2,ABL1,AKT1,WNK1,AURKB,PRKAG1,NME2,PPP1CA,MTMR4,SMG1,MAP3K2,RPS6KA1,NTRK3, |
1.98E-2 |
|
GO:0006793
|
phosphorus metabolic process |
SIK2,MAPK14,RAF1,IP6K1,PRDX2,ULK3,ND6,PRKRA,BCKDK,NDUFS7,MKNK2,MTMR3,HK2,ATP5B,ERBB2,ERBB3,BCL2,BMPR1B,EPHA7,MTMR12,FGFR2,ABL1,AKT1,WNK1,AURKB,PRKAG1,NME2,PPP1CA,MTMR4,SMG1,MAP3K2,RPS6KA1,NTRK3, |
1.98E-2 |
|
GO:0009725
|
response to hormone stimulus |
IL6R,ERBB2,STRN3,ADM,BCL2,ERBB3,STAT3,SIK2,ZFP106,CDKN1A,SORT1,AKT1,IGF2,EIF4EBP1,CCNE1,MMP13,PARP1, |
1.98E-2 |
|
GO:0006839
|
mitochondrial transport |
TIMM23,BCL2,BAK1,TIMM10,SLC25A1,TP53,HTT, |
2.07E-2 |
|
GO:0016071
|
mRNA metabolic process |
SRRM2,HSPA1B,SNRPB,KHSRP,CASC3,PCBP2,LUC7L3,CEBPG,TARDBP,RNH1,SUGP2,ESRP2,HNRNPK,DHX38,SMG1,FUS,PABPC1, |
2.15E-2 |
|
GO:0009719
|
response to endogenous stimulus |
IL6R,GRIN2A,ERBB2,STRN3,ERBB3,ADM,BCL2,STAT3,SIK2,ZFP106,CDKN1A,SORT1,AKT1,IGF2,EIF4EBP1,CCNE1,MMP13,PARP1, |
2.17E-2 |
|
GO:0051101
|
regulation of DNA binding |
IRF4,HNF4A,SMO,CEBPG,PRDX2,NPM1,NME2,CDKN2A,BCL3, |
2.32E-2 |
|
GO:0060348
|
bone development |
IGF2,CYP24A1,GLI1,BCL2,SMO,CBFB,SP7,SORT1,MMP13, |
2.57E-2 |
|
GO:0007167
|
enzyme linked receptor protein signaling pathway |
ERBB2,ERBB3,BMPR1B,STAT3,SIK2,EPHA7,RAF1,ZFP106,FGFR2,SORT1,AKT1,IGF2,LIF,EIF4EBP1,SGPL1,NTRK3, |
2.57E-2 |
|
GO:0051236
|
establishment of RNA localization |
NUP93,NPM1,KHSRP,CASC3,SMG1,NUP205,TMEM48,RANBP2, |
2.63E-2 |
|
GO:0050658
|
RNA transport |
NUP93,NPM1,KHSRP,CASC3,SMG1,NUP205,TMEM48,RANBP2, |
2.63E-2 |
|
GO:0050657
|
nucleic acid transport |
NUP93,NPM1,KHSRP,CASC3,SMG1,NUP205,TMEM48,RANBP2, |
2.63E-2 |
|
GO:0042493
|
response to drug |
ALDH1A3,ERBB2,GRIN2A,BCL2,ERBB3,STAT3,ABCC1,NME2,CDKN1A,CCNE1,TP53,NES, |
3.12E-2 |
|
GO:0006403
|
RNA localization |
NUP93,NPM1,KHSRP,CASC3,SMG1,NUP205,TMEM48,RANBP2, |
3.13E-2 |
|
GO:0007006
|
mitochondrial membrane organization |
BCL2,BAK1,TIMM10,TP53,HTT, |
3.13E-2 |
|
GO:0006913
|
nucleocytoplasmic transport |
KPNB1,NPM1,ATXN1,SMG1,AKT1,NUP205,TP53,HTT,BCL3,RANBP2, |
3.19E-2 |
|
GO:0051169
|
nuclear transport |
KPNB1,NPM1,ATXN1,SMG1,AKT1,NUP205,TP53,HTT,BCL3,RANBP2, |
3.48E-2 |
|
GO:0007569
|
cell aging |
BCL2,NPM1,CDKN2A,TP53,HTT, |
3.51E-2 |
|
GO:0045449
|
regulation of transcription |
THRAP3,STAT3,BACH1,YEATS2,MTF1,KHSRP,ZNF212,ASH2L,LIN28B,CEBPA,IGF2,SUPT6H,CRTC1,CEBPG,CREBBP,ARID3A,BCL3,PRDM1,PTOV1,ZNF395,ATXN1,HOXA13,ZNF667,ABL1,EHMT1,KLF13,NME2,SMARCD2,ETS1,LBX2,ARID3B,ZNF592,IRF4,BCOR,CBFB,MAPK14,PRDX2,SP7,CDKN2A,HMGA2,LIN28A,HNF4G,SPEN,E2F7,HNF4A,MTA2,VDR,CSRNP2,POU5F1,RYBP,USP22,CARHSP1,ZMYND11,GLI1,STRN3,NPM1,HMGA1,TP53,E2F3,E2F2,MED1,MLL2,LIF,TARDBP,HKR1,HDGF,CCNE1,TEF,ZNF483, |
3.54E-2 |
|
GO:0017038
|
protein import |
TIMM23,KPNB1,AKT1,TIMM10,NUP205,TP53,HTT,BCL3,RANBP2, |
3.78E-2 |
|
GO:0043281
|
regulation of caspase activity |
BBC3,CDKN2A,BAK1,TP53,BCL2L13,HSPD1,PMAIP1, |
4.09E-2 |
|
GO:0044093
|
positive regulation of molecular function |
IRF4,ERBB2,BCL2,NPM1,PRDX2,CDKN2A,ABL1,AKT1,TP53,MSH3,HSPD1,PMAIP1,PSMB1,IGF2,PRKAG1,CEBPG,BBC3,VDR,NME2,BAK1,MAP3K2,BCL2L13, |
4.58E-2 |
|
GO:0032268
|
regulation of cellular protein metabolic process |
IL6R,BCL2,CASC3,CDKN2A,KRT7,NRD1,AKT1,EIF5,MKNK2,PSMB1,IGF2,HNF4A,LIF,EIF4EBP1,BAK1,ETF1,MAP3K2,TNRC6B,BCL3, |
4.77E-2 |
|
GO:0006417
|
regulation of translation |
MKNK2,EIF5,CASC3,EIF4EBP1,KRT7,ETF1,AKT1,TNRC6B,BCL3, |
4.96E-2 |
|
GO:0009416
|
response to light stimulus |
GRIN2A,BCL2,ATXN1,CNGB1,CDKN1A,AKT1,TP53,HTT,BCL3, |
5.18E-2 |
|
GO:0008286
|
insulin receptor signaling pathway |
IGF2,SIK2,ZFP106,EIF4EBP1,AKT1, |
5.35E-2 |
|
GO:0001890
|
placenta development |
CEBPA,PRDM1,LIF,VDR,AKT1,MED1, |
5.82E-2 |
|
GO:0006350
|
transcription |
THRAP3,BACH1,STAT3,MTF1,KHSRP,ZNF212,ASH2L,CEBPA,SUPT6H,CRTC1,CEBPG,CREBBP,ARID3A,BCL3,PRDM1,PTOV1,ZNF395,HOXA13,ZNF667,KLF13,NME2,SMARCD2,ETS1,LBX2,ARID3B,ZNF592,ADRM1,IRF4,BCOR,CBFB,SP7,CDKN2A,HMGA2,HNF4G,SPEN,HNF4A,E2F7,VDR,CSRNP2,POU5F1,RYBP,USP22,ZMYND11,GLI1,HMGA1,E2F3,TP53,E2F2,MED1,MLL2,TARDBP,HKR1,MYEF2,HDGF,ZNF483,TEF,PARP1, |
5.87E-2 |
|
GO:0051276
|
chromosome organization |
IRF4,BCOR,NPM1,SMC2,HMGA2,HMGA1,TP53,MSH3,EHMT1,MLL2,HUWE1,TNKS1BP1,SUPT6H,HIST2H2BF,MTA2,CREBBP,USP22,SMARCD2,PARP1, |
5.94E-2 |
|
GO:0015931
|
nucleobase, nucleoside, nucleotide and nucleic acid transport |
NUP93,NPM1,KHSRP,CASC3,SMG1,NUP205,TMEM48,RANBP2, |
6.13E-2 |
|
GO:0006606
|
protein import into nucleus |
KPNB1,AKT1,NUP205,TP53,HTT,BCL3,RANBP2, |
6.20E-2 |
|
GO:0040008
|
regulation of growth |
BCL2,STAT3,CDKN2A,HMGA2,CDKN1A,AKT1,TP53,IGF2,HNF4A,BBC3,CD320,SGPL1,PARP1,NTRK3,EXTL3, |
6.31E-2 |
|
GO:0051028
|
mRNA transport |
NUP93,KHSRP,CASC3,SMG1,NUP205,TMEM48,RANBP2, |
6.56E-2 |
|
GO:0008361
|
regulation of cell size |
IGF2,HNF4A,BCL2,NPM1,FGFR2,CDKN2A,CDKN1A,AKT1,TP53,EXTL3,NTRK3, |
6.57E-2 |
|
GO:0051170
|
nuclear import |
KPNB1,AKT1,NUP205,TP53,HTT,BCL3,RANBP2, |
6.93E-2 |
|
GO:0033365
|
protein localization in organelle |
TIMM23,KPNB1,AKT1,TIMM10,NUP205,TP53,HTT,BCL3,RANBP2, |
7.22E-2 |
|
GO:0051094
|
positive regulation of developmental process |
IL6R,BCL2,BMPR1B,MAPK14,NPTN,AKT1,IGF2,SMO,LIF,NME2,ETS1,CCNE1,NTRK3, |
7.60E-2 |
|
GO:0006605
|
protein targeting |
TIMM23,KPNB1,SSR3,SSR2,AKT1,TIMM10,NUP205,TP53,HTT,BCL3,RANBP2, |
8.74E-2 |
|
GO:0008380
|
RNA splicing |
SRRM2,SNRPB,KHSRP,CASC3,PCBP2,LUC7L3,TARDBP,HNRNPK,ESRP2,SUGP2,DHX38,FUS,PABPC1, |
8.94E-2 |
|
GO:0010332
|
response to gamma radiation |
IL6R,BCL2,BAK1,TP53, |
9.35E-2 |
|
GO:0034504
|
protein localization in nucleus |
KPNB1,AKT1,NUP205,TP53,HTT,BCL3,RANBP2, |
9.47E-2 |
|
GO:0010551
|
regulation of specific transcription from RNA polymerase II promoter |
IRF4,CEBPA,HNF4A,BCOR,VDR,ETS1,TP53, |
9.47E-2 |
|
GO:0006468
|
protein amino acid phosphorylation |
ERBB2,ERBB3,BMPR1B,BCL2,SIK2,MAPK14,EPHA7,RAF1,PRDX2,ULK3,FGFR2,ABL1,PRKRA,BCKDK,AKT1,WNK1,MKNK2,AURKB,PRKAG1,SMG1,MAP3K2,RPS6KA1,NTRK3, |
9.50E-2 |
|
GO:0031670
|
cellular response to nutrient |
CYP24A1,VDR,CCNE1, |
9.54E-2 |
|
|
|
|
|
|
|