| Detail: | |
| ncRNA Symmbol: | miR-224 |
|---|---|
| ncRNA Category: | miRNA |
| Interaction Gene Symbol: | BCL2 |
| Death Pathway: | apoptosis |
| Expression Direction of ncRNA: | down |
| Species: | Homo sapiens |
| Tissue: | gastric cancer cell |
| PMID: | 24796455 |
| Detail Description: | Flow cytometry indicated that the apoptotic index was (15.68 ¡À 1.46)% in the miR-224 ASO group and (3.36 ¡À 0.88)% in the control group (P < 0.01). In addition, the expressions of Bcl2 mRNA and protein were 1.05 ¡À 0.04 and 0.21 ¡À 0.03 in the miR-224 ASO group, significantly lower than that in the control group (4.87 ¡À 0.96 and 0.88 ¡À 0.09, P < 0.01). The in vivo study further showed that the tumor volume in the experimental group is significantly smaller than that in the control group (P = 0.01). |
The 'First Node' or 'Second Node' option represents the sub-network of interacting entry with the first or second interaction node,
the 'Both the Nodes' option represents the sub-network of interacting entry with both of interaction nodes.
The 'First Neighbour' represents the sub-network of direct interacting with the center node,
the 'Second Neighbour' represents the sub-network of direct or second step interacting with the center node.
Interaction sub-network based on the two nodes of this interaction may help the researchers represents all interacting partners immediately.
The Detail page: representing the detail information for RNA-RNA/RNA-Protein interaction;
The Binding page: representing the predicted binding sites and/or constants.
The Network page: representing the interaction sub-network of interacting RNA/Protein.