Basic Information
| RNALocate ID: | RLID:20000221 |
| RNA Symbol: | EIF2S3 |
| Localization: | Neurite |
RNA Information
| RNA Name: | Eif2s3 |
| RNA ID: | NCBI:1968|Ensembl:ENSG00000130741 |
| RNA Category: | mRNA |
| Species: | Homo sapiens |
| Alias: | EIF2|EIF2G|EIF2gamma|MEHMO|MRXSBRK|eIF-2gA |
Localization Information
| PubMed ID: | 29378846 |
| Tissue/Cell Line: | HiPSC-derived neurons (iCell neurons) |
| Method: | FISH|RNA sequencing |
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Originally published in J Biol Chem. Tóth EN, et al, 2018. Reproduced under the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/) |
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| Description: | To verify the localization of these transcripts in neurites, we performed fluorescent in situ hybridization on a chosen set of genes (Fig. 3C). We selected a diverse set of genes for the validation experiment, including genes encoding nuclear proteins, a component of the translation machinery, a protein that has differential expression in brain, and a component of mitochondrial inner membrane. We put more emphasis on nuclear genes because their localization to neurites is less understood. All of the mRNAs for which we developed probes were detected in the neurites. Data are collected from Figure 3(C). |
Other Subcellular Localization
| RNALocate ID | Localization | Tissue/Cell line | PubMed ID |
| RLID:00007278 | Cytoplasm | Nasopharyngeal carcinoma cells | 20498841 |
| RLID:00007279 | Cytosol | Human myelogenous leukemia cell line (K-562) | 21613539 |
| RLID:00007280 | Nucleus | Nasopharyngeal carcinoma cells | 20498841 |
| RLID-D:00015813 | Membrane | K562 cells | |
| RLID-D:00019489 | Nucleolus | K562 cells | |
| RLID-D:00025674 | Nucleoplasm | K562 cells | |
| RLID-D:00033465 | Nucleus | HCC cell line (HepG2)|HeLa-S3 cells | |
| RLID-D:10003717 | Exosome | Blood |
RNA Interaction Information
| Resource | RNA Symbol | Species | Link | RNALocate ID |
| RNAInter | SNHG16 | Homo sapiens | RR00490181 |
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