Basic Information
| RNALocate ID: | RLID:11004691 |
| RNA Symbol: | hsa-miR-3065-5p |
| Localization: | Exosome |
RNA Information
| RNA Name: | hsa-miR-3065-5p |
| RNA ID: | miRBase:MIMAT0015066 |
| RNA Category: | miRNA |
| Species: | Homo sapiens |
Localization Information
| PubMed ID: | 25349172 |
| Tissue/Cell Line: | Serum |
| Method: | Next-generation RNA sequencing |
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Originally published in Mol Psychiatry. Cheng L, et al, 2015. Reproduced under the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/) |
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| Description: | Deep sequencing of the exosomal RNA extracted from serum samples was performed and sequences were mapped to miRBase Exosomal miRNA biomarkers for Alzheimer's disease. Approximately half of the reads obtained (43%) from small RNA sequencing corresponded with miRNA sequences (Supplementary Table 1). Overall, the sample cohort mapped to 1419 known human miRNA sequences (Supplementary Table 2). Following normalisation of reads and performing ANOVA analyses, 17 miRNA were found to be significantly deregulated (Figure 1); 14 miRNA were found to be upregulated (hsa-miR-361-5p, hsa-miR-30e-5p, hsa-miR-93-5p, hsa-miR-15a-5p, hsa-miR-143-3p, hsa-miR-335-5p, hsa-miR-106b-5p, hsa-miR-101-3p, hsa-miR-424-5p, hsa-miR-106a-5p, hsa-miR-18b-5p, hsa-miR-3065-5p, hsa-miR-20a-5p and hsa-miR-582-5p) and three miRNA were found to be downregulated (hsa-miR-1306-5p, hsa-miR-342-3p and 15b-3p; Table 2). Data are collected from Table 2. |
Other Subcellular Localization
| RNALocate ID | Localization | Tissue/Cell line | PubMed ID |
| RLID:11004690 | Exosome | Plasma | 23663360 |
| RLID:11004692 | Microvesicle | Seminal plasma | 23539611 |
| RLID-D:11000864 | Microvesicle | Colon cancer cell line (LIM1863)|Fibroblasts|Mesenchymal stem cells | |
| RLID-D:11001892 | Exosome | Breast milk|Cell lines|Epididymal epithelial cells|Osteoblast|Plasma|Primary glioblastoma neurosphere cells|Primary keratinocyte|Saliva|Serum|Urine |
ncRNA Disease Information
| Resource | RNA Symbol | Disease | Link |
| MNDR | hsa-miR-3065-5p | Uterine corpus endometrial carcinoma | MNDR-E-MI-36402 |
| MNDR | hsa-miR-3065-5p | Alzheimer disease | MNDR-E-MI-36403 |
| MNDR | hsa-miR-3065-5p | Polycystic ovary syndrome | MNDR-E-MI-36404 |
| MNDR | hsa-miR-3065-5p | Huntington disease | MNDR-E-MI-36405 |
| MNDR | hsa-miR-3065-5p | Chorea | MNDR-E-MI-36406 |
| MNDR | hsa-miR-3065-5p | Parkinson disease | MNDR-E-MI-36407 |
| MNDR | hsa-miR-3065-5p | Rectum adenocarcinoma | MNDR-E-MI-36408 |
| MNDR | hsa-miR-3065-5p | Prostate adenocarcinoma | MNDR-E-MI-36409 |
| MNDR | hsa-miR-3065-5p | Carcinoma ductal breast | MNDR-E-MI-36410 |
| MNDR | hsa-miR-3065-5p | Lung squamous cell carcinoma | MNDR-E-MI-36411 |
| MNDR | hsa-miR-3065-5p | Thyroid carcinoma | MNDR-E-MI-36412 |
| MNDR | hsa-miR-3065-5p | Bladder urothelial carcinoma | MNDR-E-MI-36413 |
| MNDR | hsa-miR-3065-5p | Pancreatic adenocarcinoma | MNDR-E-MI-36414 |
| MNDR | hsa-miR-3065-5p | Kidney renal clear cell carcinoma | MNDR-E-MI-36415 |
| MNDR | hsa-miR-3065-5p | Kidney renal papillary cell carcinoma | MNDR-E-MI-36416 |
| MNDR | hsa-miR-3065-5p | Renal clear cell carcinoma | MNDR-E-MI-36417 |
| MNDR | hsa-miR-3065-5p | Cholangiocarcinoma | MNDR-E-MI-36418 |
| MNDR | hsa-miR-3065-5p | Breast invasive carcinoma | MNDR-E-MI-36419 |
RNA Interaction Information
| Resource | RNA Symbol | Species | Link | RNALocate ID |
| RNAInter | SNHG16 | Homo sapiens | RR01338248 |
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