Basic Information
RNALocate ID: | RLID:11003785 |
RNA Symbol: | hsa-miR-149-3p |
Localization: | Exosome |
RNA Information
RNA Name: | hsa-miR-149* |
RNA ID: | miRBase:MIMAT0004609 |
RNA Category: | miRNA |
Species: | Homo sapiens |
Localization Information
PubMed ID: | 24468161 |
Tissue/Cell Line: | Breast cancer cell lines (MCF-7|MDA-MB-231) |
Method: | Microarray|RT-PCR |
Quantitative real-time PCR of miRNAs performed to validate the microarray data. Down-regulation of mir-198 in MCF-Exo and up-regulation of let-7a, mir-328, mir-130a, mir-149, mir-603, and mir-92b from microarray experiments were validated by quantitative PCR analysis (*P < 0.01). Originally published in BMC Cancer. Kruger S, et al, 2014. Reproduced under the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/) |
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Description: | Differential gene expression in exosome-like vesicles. A) Hierarchical clustering was used to display miRNAs differentially expressed in each vesicle type. The extent of green (decreased fold change) or red (increased fold change) colors is directly proportional to the magnitude of differential expression of miRNAs. B) miRNA profiles of the MDA-Exo versus MCF-Exo. Bars represent fold change of hybridization signals in MDA-Exo against MCF-Exo. Blue and red bars display relatively higher miRNA expressions in MDA-Exo and MCF-Exo, respectively. Data are collected from Figure 3. |
Other Subcellular Localization
RNALocate ID | Localization | Tissue/Cell line | PubMed ID |
RLID:01002607 | Mitochondrion | Cell line (HEK-293) | 22984580 |
RLID:11003781 | Exosome | Breast cancer cell line (MCF-7) | 20976003 |
RLID:11003782 | Exosome | B cell line (Raji)|Jurkat-derived T cell line (J77cl20) | 21505438 |
RLID:11003783 | Exosome | Plasma | 23663360 |
RLID:11003784 | Exosome | K562 cells | 24460325 |
RLID:11003786 | Microvesicle | Seminal plasma | 23539611 |
RLID-D:11000639 | Microvesicle | Fibroblasts|Mesenchymal stem cells | |
RLID-D:11001514 | Exosome | Breast milk|Cell lines|Epididymal epithelial cells|Osteoblast|Plasma|Primary glioblastoma neurosphere cells|Primary keratinocyte|Saliva|Serum|Urine |
ncRNA Disease Information
Resource | RNA Symbol | Disease | Link |
MNDR | hsa-miR-149-3p | Oral squamous cell carcinoma | MNDR-E-MI-16266 |
MNDR | hsa-miR-149-3p | Medulloblastoma | MNDR-E-MI-16267 |
MNDR | hsa-miR-149-3p | Lymphoma | MNDR-E-MI-16268 |
MNDR | hsa-miR-149-3p | Estrogen-receptor positive breast cancer | MNDR-E-MI-16269 |
MNDR | hsa-miR-149-3p | Estrogen-receptor negative breast cancer | MNDR-E-MI-16270 |
MNDR | hsa-miR-149-3p | Progesterone-receptor positive breast cancer | MNDR-E-MI-16271 |
MNDR | hsa-miR-149-3p | Progesterone-receptor negative breast cancer | MNDR-E-MI-16272 |
MNDR | hsa-miR-149-3p | Her2-receptor positive breast cancer | MNDR-E-MI-16273 |
MNDR | hsa-miR-149-3p | Breast cancer luminal | MNDR-E-MI-16274 |
MNDR | hsa-miR-149-3p | Prostate cancer | MNDR-E-MI-16275 |
MNDR | hsa-miR-149-3p | Gastric cancer | MNDR-E-MI-16276 |
MNDR | hsa-miR-149-3p | Intracranial aneurysm | MNDR-E-MI-16277 |
MNDR | hsa-miR-149-3p | Lung cancer | MNDR-E-MI-16278 |
MNDR | hsa-miR-149-3p | Parkinson disease | MNDR-E-MI-16279 |
MNDR | hsa-miR-149-3p | Basal-like breast cancer | MNDR-E-MI-16280 |
MNDR | hsa-miR-149-3p | Pancreatic cancer | MNDR-E-MI-16281 |
MNDR | hsa-miR-149-3p | HCV | MNDR-E-MI-16282 |
MNDR | hsa-miR-149-3p | Nephroblastoma | MNDR-E-MI-16283 |
MNDR | hsa-miR-149-3p | Colon cancer | MNDR-E-MI-16284 |
MNDR | hsa-miR-149-3p | Familial ovarian cancer | MNDR-E-MI-16285 |
MNDR | hsa-miR-149-3p | Glioblastoma | MNDR-E-MI-16286 |
MNDR | hsa-miR-149-3p | Glioma | MNDR-E-MI-16287 |
MNDR | hsa-miR-149-3p | Chordoma | MNDR-E-MI-16288 |
MNDR | hsa-miR-149-3p | Amyotrophic lateral sclerosis | MNDR-E-MI-16289 |
MNDR | hsa-miR-149-3p | Osteosarcoma | MNDR-E-MI-16290 |
MNDR | hsa-miR-149-3p | Breast carcinoma | MNDR-E-MI-16291 |
MNDR | hsa-miR-149-3p | Infarction middle cerebral artery | MNDR-E-MI-16292 |
MNDR | hsa-miR-149-3p | Lung squamous cell carcinoma | MNDR-E-MI-16293 |
MNDR | hsa-miR-149-3p | Lung adenocarcinoma | MNDR-E-MI-16294 |
MNDR | hsa-miR-149-3p | Bladder urothelial carcinoma | MNDR-E-MI-16295 |
MNDR | hsa-miR-149-3p | Cholangiocarcinoma | MNDR-E-MI-16296 |
MNDR | hsa-miR-149-3p | Esophageal cancer | MNDR-E-MI-16297 |
MNDR | hsa-miR-149-3p | Lung small cell carcinoma | MNDR-E-MI-16298 |
MNDR | hsa-miR-149-3p | Head and neck squamous cell carcinoma | MNDR-E-MI-16299 |
MNDR | hsa-miR-149-3p | Hepatocellular carcinoma | MNDR-E-MI-16300 |
MNDR | hsa-miR-149-3p | Familiar ovarian carcinoma | MNDR-E-MI-16301 |
MNDR | hsa-miR-149-3p | Retinoblastoma | MNDR-E-MI-16302 |
MNDR | hsa-miR-149-3p | Neuroblastoma | MNDR-E-MI-16303 |
MNDR | hsa-miR-149-3p | Hodgkin lymphoma | MNDR-E-MI-16304 |
MNDR | hsa-miR-149-3p | Colorectal cancer | MNDR-E-MI-16305 |
MNDR | hsa-miR-149-3p | Nasopharynx carcinoma | MNDR-E-MI-16306 |
MNDR | hsa-miR-149-3p | Nasopharyngeal cancer | MNDR-E-MI-16307 |
MNDR | hsa-miR-149-3p | Subarachnoid hemorrhage traumatic | MNDR-E-MI-16308 |
MNDR | hsa-miR-149-3p | Stroke lacunar | MNDR-E-MI-16309 |
MNDR | hsa-miR-149-3p | Breast cancer her3+ negative | MNDR-E-MI-16310 |
RNA Interaction Information
Resource | RNA Symbol | Species | Link | RNALocate ID |
RNAInter | AKT1 | Homo sapiens | RR00066993 |
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