Basic Information
RNALocate ID: RLID:11002421
RNA Symbol: hsa-miR-361-5p
Localization: Exosome
RNA Information
RNA Name: hsa-miR-361-5p
RNA ID: miRBase:MIMAT0000703
RNA Category: miRNA
Species: Homo sapiens
Sequence:
Localization Information
PubMed ID: 25349172
Tissue/Cell Line: Serum
Method: Next-generation RNA sequencing

Originally published in Mol Psychiatry. Cheng L, et al, 2015. Reproduced under the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/)
Description: Deep sequencing of the exosomal RNA extracted from serum samples was performed and sequences were mapped to miRBase Exosomal miRNA biomarkers for Alzheimer's disease. Approximately half of the reads obtained (43%) from small RNA sequencing corresponded with miRNA sequences (Supplementary Table 1). Overall, the sample cohort mapped to 1419 known human miRNA sequences (Supplementary Table 2). Following normalisation of reads and performing ANOVA analyses, 17 miRNA were found to be significantly deregulated (Figure 1); 14 miRNA were found to be upregulated (hsa-miR-361-5p, hsa-miR-30e-5p, hsa-miR-93-5p, hsa-miR-15a-5p, hsa-miR-143-3p, hsa-miR-335-5p, hsa-miR-106b-5p, hsa-miR-101-3p, hsa-miR-424-5p, hsa-miR-106a-5p, hsa-miR-18b-5p, hsa-miR-3065-5p, hsa-miR-20a-5p and hsa-miR-582-5p) and three miRNA were found to be downregulated (hsa-miR-1306-5p, hsa-miR-342-3p and 15b-3p; Table 2). Data are collected from Table 2.
Other Subcellular Localization
RNALocate ID Localization Tissue/Cell line PubMed ID
RLID:01002009 Cytoplasm Nasopharyngeal carcinoma cells 20498841
RLID:01002010 Cytoplasm Neural progenitor cells 21363885
RLID:01002011 Cytoplasm Breast adenocarcinoma cells (MCF-7)|Cervical adenocarcinoma cells (HeLa) 24918059
RLID:01002012 Mitochondrion Cell line (HEK-293|HeLa) 22984580
RLID:01002013 Nucleus Breast adenocarcinoma cells (MCF-7)|Cervical adenocarcinoma cells (HeLa) 24918059
RLID:01002014 Nucleus Nasopharyngeal carcinoma cells 20498841
RLID:11002414 Exosome Serum 18589210
RLID:11002415 Exosome Breast cancer cell line (MCF-7) 20976003
RLID:11002416 Exosome Primary dendritic cells|T cell line (J77) 21505438
RLID:11002417 Exosome Renal cancer cells 21670082
RLID:11002418 Exosome Brain tissue 23382797
RLID:11002419 Exosome Plasma 23663360
RLID:11002420 Exosome Human mast cell line (HMC-1) 24009880
RLID:11002422 Extracellular vesicle HEK-293T cells 22849433
RLID:11002423 Microvesicle Seminal plasma 23539611
RLID-D:11000117 Exosome Blood|Kidney tissue
RLID-D:11000406 Microvesicle Blood|Colon cancer cell line (LIM1863)|Fibroblasts|Mesenchymal stem cells|Urine
ncRNA Disease Information
Resource RNA Symbol Disease Link
MNDR hsa-miR-361-5p Oral squamous cell carcinoma MNDR-E-MI-43463
MNDR hsa-miR-361-5p Medulloblastoma MNDR-E-MI-43464
MNDR hsa-miR-361-5p Uterine corpus endometrial carcinoma MNDR-E-MI-43465
MNDR hsa-miR-361-5p Lymphoma MNDR-E-MI-43466
MNDR hsa-miR-361-5p Estrogen-receptor positive breast cancer MNDR-E-MI-43467
MNDR hsa-miR-361-5p Estrogen-receptor negative breast cancer MNDR-E-MI-43468
MNDR hsa-miR-361-5p Progesterone-receptor positive breast cancer MNDR-E-MI-43469
MNDR hsa-miR-361-5p Progesterone-receptor negative breast cancer MNDR-E-MI-43470
MNDR hsa-miR-361-5p Her2-receptor positive breast cancer MNDR-E-MI-43471
MNDR hsa-miR-361-5p Precursor cell lymphoblastic leukemia-lymphoma MNDR-E-MI-43472
MNDR hsa-miR-361-5p B cell acute lymphoblastic leukemia MNDR-E-MI-43473
MNDR hsa-miR-361-5p Dermatomyositis MNDR-E-MI-43474
MNDR hsa-miR-361-5p Prostate cancer MNDR-E-MI-43475
MNDR hsa-miR-361-5p Gastric cancer MNDR-E-MI-43476
MNDR hsa-miR-361-5p Alzheimer disease MNDR-E-MI-43477
MNDR hsa-miR-361-5p Intracranial aneurysm MNDR-E-MI-43478
MNDR hsa-miR-361-5p Dysautonomia familial MNDR-E-MI-43479
MNDR hsa-miR-361-5p Muscular dystrophy duchenne MNDR-E-MI-43480
MNDR hsa-miR-361-5p Primary biliary cirrhosis MNDR-E-MI-43481
MNDR hsa-miR-361-5p Graves disease MNDR-E-MI-43482
MNDR hsa-miR-361-5p Leukemia MNDR-E-MI-43483
MNDR hsa-miR-361-5p Cardiovascular disease MNDR-E-MI-43484
MNDR hsa-miR-361-5p Carotid stenosis MNDR-E-MI-43485
MNDR hsa-miR-361-5p Moyamoya disease MNDR-E-MI-43486
MNDR hsa-miR-361-5p Lung cancer MNDR-E-MI-43487
MNDR hsa-miR-361-5p Parkinson disease MNDR-E-MI-43488
MNDR hsa-miR-361-5p Breast cancer MNDR-E-MI-43489
MNDR hsa-miR-361-5p Pituitary neoplasms MNDR-E-MI-43490
MNDR hsa-miR-361-5p Pancreatic cancer MNDR-E-MI-43491
MNDR hsa-miR-361-5p Melanoma MNDR-E-MI-43492
MNDR hsa-miR-361-5p Nephroblastoma MNDR-E-MI-43493
MNDR hsa-miR-361-5p Colon cancer MNDR-E-MI-43494
MNDR hsa-miR-361-5p Relapsing-remitting multiple sclerosis MNDR-E-MI-43495
MNDR hsa-miR-361-5p Ovarian cancer MNDR-E-MI-43496
MNDR hsa-miR-361-5p Prostate adenocarcinoma MNDR-E-MI-43497
MNDR hsa-miR-361-5p Carcinoma ductal breast MNDR-E-MI-43498
MNDR hsa-miR-361-5p Glioblastoma MNDR-E-MI-43499
MNDR hsa-miR-361-5p Glioma MNDR-E-MI-43500
MNDR hsa-miR-361-5p Central nervous system lymphoma MNDR-E-MI-43501
MNDR hsa-miR-361-5p Chordoma MNDR-E-MI-43502
MNDR hsa-miR-361-5p Amyotrophic lateral sclerosis MNDR-E-MI-43503
MNDR hsa-miR-361-5p Epilepsy temporal lobe MNDR-E-MI-43504
MNDR hsa-miR-361-5p Osteosarcoma MNDR-E-MI-43505
MNDR hsa-miR-361-5p Inclusion body myositis MNDR-E-MI-43506
MNDR hsa-miR-361-5p Pancreatic ductal adenocarcinoma MNDR-E-MI-43507
MNDR hsa-miR-361-5p Gastric adenocarcinoma MNDR-E-MI-43508
MNDR hsa-miR-361-5p Cervical squamous cell carcinoma MNDR-E-MI-43509
MNDR hsa-miR-361-5p Pituitary adenoma MNDR-E-MI-43510
MNDR hsa-miR-361-5p Lung squamous cell carcinoma MNDR-E-MI-43511
MNDR hsa-miR-361-5p Non-small cell lung cancer MNDR-E-MI-43512
MNDR hsa-miR-361-5p Lung adenocarcinoma MNDR-E-MI-43513
MNDR hsa-miR-361-5p Adrenocortical cancer MNDR-E-MI-43514
MNDR hsa-miR-361-5p Thyroid carcinoma MNDR-E-MI-43515
MNDR hsa-miR-361-5p Papillary thyroid carcinoma MNDR-E-MI-43516
MNDR hsa-miR-361-5p Bladder urothelial carcinoma MNDR-E-MI-43517
MNDR hsa-miR-361-5p Pancreatic adenocarcinoma MNDR-E-MI-43518
MNDR hsa-miR-361-5p Carcinoma renal cell MNDR-E-MI-43519
MNDR hsa-miR-361-5p Kidney renal papillary cell carcinoma MNDR-E-MI-43520
MNDR hsa-miR-361-5p Clear cell renal cell carcinoma MNDR-E-MI-43521
MNDR hsa-miR-361-5p Cholangiocarcinoma MNDR-E-MI-43522
MNDR hsa-miR-361-5p Pancreatitis MNDR-E-MI-43523
MNDR hsa-miR-361-5p Esophageal cancer MNDR-E-MI-43524
MNDR hsa-miR-361-5p Lung small cell carcinoma MNDR-E-MI-43525
MNDR hsa-miR-361-5p Encephalopathy bovine spongiform MNDR-E-MI-43526
MNDR hsa-miR-361-5p Synovial sarcoma MNDR-E-MI-43527
MNDR hsa-miR-361-5p Head and neck squamous cell carcinoma MNDR-E-MI-43528
MNDR hsa-miR-361-5p Adenoma MNDR-E-MI-43529
MNDR hsa-miR-361-5p Breast invasive carcinoma MNDR-E-MI-43530
MNDR hsa-miR-361-5p Hepatocellular carcinoma MNDR-E-MI-43531
MNDR hsa-miR-361-5p B-cell lymphoma MNDR-E-MI-43532
MNDR hsa-miR-361-5p Rheumatoid arthritis MNDR-E-MI-43533
MNDR hsa-miR-361-5p Hodgkin lymphoma MNDR-E-MI-43534
MNDR hsa-miR-361-5p Burkitt lymphoma MNDR-E-MI-43535
MNDR hsa-miR-361-5p Neuromyelitis optica MNDR-E-MI-43536
MNDR hsa-miR-361-5p Colorectal cancer MNDR-E-MI-43537
MNDR hsa-miR-361-5p Nasopharynx carcinoma MNDR-E-MI-43538
MNDR hsa-miR-361-5p Nasopharyngeal cancer MNDR-E-MI-43539
MNDR hsa-miR-361-5p Stroke lacunar MNDR-E-MI-43540
MNDR hsa-miR-361-5p Breast cancer her3+ negative MNDR-E-MI-43541
MNDR hsa-miR-361-5p Cutaneous squamous cell carcinoma MNDR-E-MI-43542
MNDR hsa-miR-361-5p Solid-pseudopapillary neoplasm of pancreas MNDR-E-MI-43543
MNDR hsa-miR-361-5p Tubulovillous adenoma MNDR-E-MI-43544
RNA Interaction Information
Resource RNA Symbol Species Link RNALocate ID
RNAInter ABCB1 Homo sapiens RR00022785
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