Basic Information
| RNALocate ID: | RLID:11001698 |
| RNA Symbol: | hsa-miR-30b-5p |
| Localization: | Exosome |
RNA Information
| RNA Name: | hsa-miR-30b-5p |
| RNA ID: | miRBase:MIMAT0000420 |
| RNA Category: | miRNA |
| Species: | Homo sapiens |
Localization Information
| PubMed ID: | 22211110 |
| Tissue/Cell Line: | Breast milk |
| Method: | Next-generation RNA sequencing |
|
The expression profile of selected miRNAs in breast milk exosomes. Originally published in Int J Biol Sci. Zhou Q, et al, 2012. Reproduced under the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/) |
|
| Description: | Distribution and characterization of miRNAs in breast milk exosomes. (A) Distribution of pre-miRNAs. Out of 1,424 pre-miRNAs deposited in miRBase 17.0 (blue circle), 87 (6.11%) pre-miRNAs have been designated as immune-related pre-miRNAs based on annotation in the Pathway Central database (SABiosciences, MD, USA). Immune-related pre-miRNAs (59 of 452, 13.05%) are enriched in breast milk exosomes (red circle). χ2 test: Number of immune-related miRNAs and others detected in breast milk exosomes compared with the total entries in miRBase 17.0. (B) Top ten most highly expressed unique miRNAs. Plot of the unique miRNAs (starting from the miRNA with the highest counts, x-axis) versus their cumulative % of the total counts from 602 unique miRNAs detected in breast milk exosomes for each small RNA library. Values are means ± s.d. The dashed horizontal line at 62.3% represents the level of the top ten unique miRNAs and the % of individual miRNAs is marked by the gray line. (C-E) The expression profile of selected miRNAs in breast milk exosomes. (C) 59 immune-related pre-miRNAs; (D) miR-17-92 cluster and paralogous clusters, and (E) ten well-characterized tissue-specific pre-miRNAs. Data are collected from Figure 2. |
Other Subcellular Localization
| RNALocate ID | Localization | Tissue/Cell line | PubMed ID |
| RLID:01001739 | Cytoplasm | Breast adenocarcinoma cells (MCF-7)|Cervical adenocarcinoma cells (HeLa) | 24918059 |
| RLID:01001740 | Mitochondrion | Skeletal muscle myoblasts | 21637849 |
| RLID:01001741 | Nucleus | Breast adenocarcinoma cells (MCF-7)|Cervical adenocarcinoma cells (HeLa) | 24918059 |
| RLID:01001742 | Nucleus | Neural progenitor cells | 21363885 |
| RLID:01001743 | Plasma membrane vesicle | Ad293 cells | 27165101 |
| RLID:11001694 | Exosome | Human milk | 28688106 |
| RLID:11001695 | Exosome | Plasma | 30154547 |
| RLID:11001696 | Exosome | Breast cancer cell line (MCF-7) | 20976003 |
| RLID:11001697 | Exosome | Primary dendritic cells|T cell line (J77) | 21505438 |
| RLID:11001699 | Exosome | Brain tissue | 23382797 |
| RLID:11001700 | Exosome | Plasma | 23663360 |
| RLID:11001701 | Exosome | Human mast cell line (HMC-1) | 24009880 |
| RLID:11001702 | Extracellular vesicle | HEK-293T cells | 22849433 |
| RLID:11001703 | Microvesicle | Seminal plasma | 23539611 |
| RLID:11001704 | Microvesicle | Follicular fluid | 23666971 |
| RLID-D:11000073 | Exosome | B lymphoblastoid cells|Breast milk|Chronic lymphocytic leukemia cells|Endothelial cells|Epithelial cells|Lymphoma tissue|Mast cells|Tongue tissue | |
| RLID-D:11000348 | Microvesicle | Colon cancer cell line (LIM1863)|Fibroblasts|Mesenchymal stem cells|Urine |
ncRNA Disease Information
| Resource | RNA Symbol | Disease | Link |
| MNDR | hsa-miR-30b-5p | Splenic marginal zone lymphoma | MNDR-E-MI-36938 |
| MNDR | hsa-miR-30b-5p | Multiple sclerosis chronic progressive | MNDR-E-MI-36939 |
| MNDR | hsa-miR-30b-5p | Glomerulosclerosis | MNDR-E-MI-36940 |
| MNDR | hsa-miR-30b-5p | Oral squamous cell carcinoma | MNDR-E-MI-36941 |
| MNDR | hsa-miR-30b-5p | Large cell neuroendocrine cancer | MNDR-E-MI-36942 |
| MNDR | hsa-miR-30b-5p | Medulloblastoma | MNDR-E-MI-36943 |
| MNDR | hsa-miR-30b-5p | B cell lymphoma of malt type | MNDR-E-MI-36944 |
| MNDR | hsa-miR-30b-5p | Uterine corpus endometrial carcinoma | MNDR-E-MI-36945 |
| MNDR | hsa-miR-30b-5p | Lymphoma | MNDR-E-MI-36946 |
| MNDR | hsa-miR-30b-5p | Lymphoma non-hodgkin | MNDR-E-MI-36947 |
| MNDR | hsa-miR-30b-5p | Estrogen-receptor positive breast cancer | MNDR-E-MI-36948 |
| MNDR | hsa-miR-30b-5p | Estrogen-receptor negative breast cancer | MNDR-E-MI-36949 |
| MNDR | hsa-miR-30b-5p | Progesterone-receptor positive breast cancer | MNDR-E-MI-36950 |
| MNDR | hsa-miR-30b-5p | Progesterone-receptor negative breast cancer | MNDR-E-MI-36951 |
| MNDR | hsa-miR-30b-5p | Her2-receptor positive breast cancer | MNDR-E-MI-36952 |
| MNDR | hsa-miR-30b-5p | Niemann-pick disease type c | MNDR-E-MI-36953 |
| MNDR | hsa-miR-30b-5p | Dermatomyositis | MNDR-E-MI-36954 |
| MNDR | hsa-miR-30b-5p | Prostate cancer | MNDR-E-MI-36955 |
| MNDR | hsa-miR-30b-5p | Gastric cancer | MNDR-E-MI-36956 |
| MNDR | hsa-miR-30b-5p | Gastric lymphoma | MNDR-E-MI-36957 |
| MNDR | hsa-miR-30b-5p | Alzheimer disease | MNDR-E-MI-36958 |
| MNDR | hsa-miR-30b-5p | Hypertension | MNDR-E-MI-36959 |
| MNDR | hsa-miR-30b-5p | Intracranial aneurysm | MNDR-E-MI-36960 |
| MNDR | hsa-miR-30b-5p | Esophageal carcinoma | MNDR-E-MI-36961 |
| MNDR | hsa-miR-30b-5p | Dysautonomia familial | MNDR-E-MI-36962 |
| MNDR | hsa-miR-30b-5p | Myotonic dystrophy | MNDR-E-MI-36963 |
| MNDR | hsa-miR-30b-5p | Muscular dystrophy duchenne | MNDR-E-MI-36964 |
| MNDR | hsa-miR-30b-5p | Seizures | MNDR-E-MI-36965 |
| MNDR | hsa-miR-30b-5p | Head and neck cancer | MNDR-E-MI-36966 |
| MNDR | hsa-miR-30b-5p | Leukemia | MNDR-E-MI-36967 |
| MNDR | hsa-miR-30b-5p | Huntington disease | MNDR-E-MI-36968 |
| MNDR | hsa-miR-30b-5p | Chorea | MNDR-E-MI-36969 |
| MNDR | hsa-miR-30b-5p | Cardiovascular disease | MNDR-E-MI-36970 |
| MNDR | hsa-miR-30b-5p | Lung cancer | MNDR-E-MI-36971 |
| MNDR | hsa-miR-30b-5p | Down syndrome | MNDR-E-MI-36972 |
| MNDR | hsa-miR-30b-5p | Parkinson disease | MNDR-E-MI-36973 |
| MNDR | hsa-miR-30b-5p | Niemann-pick disease | MNDR-E-MI-36974 |
| MNDR | hsa-miR-30b-5p | Breast cancer | MNDR-E-MI-36975 |
| MNDR | hsa-miR-30b-5p | Pituitary neoplasms | MNDR-E-MI-36976 |
| MNDR | hsa-miR-30b-5p | Pancreatic cancer | MNDR-E-MI-36977 |
| MNDR | hsa-miR-30b-5p | Melanoma | MNDR-E-MI-36978 |
| MNDR | hsa-miR-30b-5p | Rectum adenocarcinoma | MNDR-E-MI-36979 |
| MNDR | hsa-miR-30b-5p | Nephroblastoma | MNDR-E-MI-36980 |
| MNDR | hsa-miR-30b-5p | Colon cancer | MNDR-E-MI-36981 |
| MNDR | hsa-miR-30b-5p | Colon adenocarcinoma | MNDR-E-MI-36982 |
| MNDR | hsa-miR-30b-5p | Multiple sclerosis relapsing-remitting | MNDR-E-MI-36983 |
| MNDR | hsa-miR-30b-5p | Ovarian cancer | MNDR-E-MI-36984 |
| MNDR | hsa-miR-30b-5p | Acromegaly | MNDR-E-MI-36985 |
| MNDR | hsa-miR-30b-5p | Prostate adenocarcinoma | MNDR-E-MI-36986 |
| MNDR | hsa-miR-30b-5p | Carcinoma ductal breast | MNDR-E-MI-36987 |
| MNDR | hsa-miR-30b-5p | Glioblastoma | MNDR-E-MI-36988 |
| MNDR | hsa-miR-30b-5p | Glioma | MNDR-E-MI-36989 |
| MNDR | hsa-miR-30b-5p | Nemaline myopathy | MNDR-E-MI-36990 |
| MNDR | hsa-miR-30b-5p | Central nervous system lymphoma | MNDR-E-MI-36991 |
| MNDR | hsa-miR-30b-5p | Amyotrophic lateral sclerosis | MNDR-E-MI-36992 |
| MNDR | hsa-miR-30b-5p | Temporal lobe epilepsy | MNDR-E-MI-36993 |
| MNDR | hsa-miR-30b-5p | Inclusion body myositis | MNDR-E-MI-36994 |
| MNDR | hsa-miR-30b-5p | Pancreatic ductal adenocarcinoma | MNDR-E-MI-36995 |
| MNDR | hsa-miR-30b-5p | Gastric adenocarcinoma | MNDR-E-MI-36996 |
| MNDR | hsa-miR-30b-5p | Cervical squamous cell carcinoma | MNDR-E-MI-36997 |
| MNDR | hsa-miR-30b-5p | Pituitary adenoma | MNDR-E-MI-36998 |
| MNDR | hsa-miR-30b-5p | Lung squamous cell carcinoma | MNDR-E-MI-36999 |
| MNDR | hsa-miR-30b-5p | Carcinoma lung non-small-cell | MNDR-E-MI-37000 |
| MNDR | hsa-miR-30b-5p | Lung adenocarcinoma | MNDR-E-MI-37001 |
| MNDR | hsa-miR-30b-5p | Thyroid carcinoma | MNDR-E-MI-37002 |
| MNDR | hsa-miR-30b-5p | Bladder urothelial carcinoma | MNDR-E-MI-37003 |
| MNDR | hsa-miR-30b-5p | Pancreatic adenocarcinoma | MNDR-E-MI-37004 |
| MNDR | hsa-miR-30b-5p | Carcinoma renal cell | MNDR-E-MI-37005 |
| MNDR | hsa-miR-30b-5p | Kidney renal papillary cell carcinoma | MNDR-E-MI-37006 |
| MNDR | hsa-miR-30b-5p | Clear cell renal cell carcinoma | MNDR-E-MI-37007 |
| MNDR | hsa-miR-30b-5p | Cholangiocarcinoma | MNDR-E-MI-37008 |
| MNDR | hsa-miR-30b-5p | Esophageal cancer | MNDR-E-MI-37009 |
| MNDR | hsa-miR-30b-5p | Liver cirrhosis | MNDR-E-MI-37010 |
| MNDR | hsa-miR-30b-5p | Lung small cell carcinoma | MNDR-E-MI-37011 |
| MNDR | hsa-miR-30b-5p | Head and neck squamous cell carcinoma | MNDR-E-MI-37012 |
| MNDR | hsa-miR-30b-5p | T acute lymphoblastic leukemia | MNDR-E-MI-37013 |
| MNDR | hsa-miR-30b-5p | Acute t cell leukemia | MNDR-E-MI-37014 |
| MNDR | hsa-miR-30b-5p | Growth hormone-secreting pituitary adenoma | MNDR-E-MI-37015 |
| MNDR | hsa-miR-30b-5p | Fibromyalgia | MNDR-E-MI-37016 |
| MNDR | hsa-miR-30b-5p | Breast invasive carcinoma | MNDR-E-MI-37017 |
| MNDR | hsa-miR-30b-5p | Hepatocellular carcinoma | MNDR-E-MI-37018 |
| MNDR | hsa-miR-30b-5p | B-cell lymphoma | MNDR-E-MI-37019 |
| MNDR | hsa-miR-30b-5p | Rheumatoid arthritis | MNDR-E-MI-37020 |
| MNDR | hsa-miR-30b-5p | T-cell leukemia | MNDR-E-MI-37021 |
| MNDR | hsa-miR-30b-5p | Retinoblastoma | MNDR-E-MI-37022 |
| MNDR | hsa-miR-30b-5p | Barrett's adenocarcinoma | MNDR-E-MI-37023 |
| MNDR | hsa-miR-30b-5p | Hodgkin lymphoma | MNDR-E-MI-37024 |
| MNDR | hsa-miR-30b-5p | Burkitt lymphoma | MNDR-E-MI-37025 |
| MNDR | hsa-miR-30b-5p | Tonsil cancer | MNDR-E-MI-37026 |
| MNDR | hsa-miR-30b-5p | Neuromyelitis optica | MNDR-E-MI-37027 |
| MNDR | hsa-miR-30b-5p | Acute myelogenous leukemia | MNDR-E-MI-37028 |
| MNDR | hsa-miR-30b-5p | Colorectal cancer | MNDR-E-MI-37029 |
| MNDR | hsa-miR-30b-5p | Nasopharynx carcinoma | MNDR-E-MI-37030 |
| MNDR | hsa-miR-30b-5p | Ependymoma | MNDR-E-MI-37031 |
| MNDR | hsa-miR-30b-5p | Cardiomegaly | MNDR-E-MI-37032 |
| MNDR | hsa-miR-30b-5p | Nasopharyngeal cancer | MNDR-E-MI-37033 |
| MNDR | hsa-miR-30b-5p | Epstein-barr virus infections | MNDR-E-MI-37034 |
| MNDR | hsa-miR-30b-5p | Cerebral hemorrhage traumatic | MNDR-E-MI-37035 |
| MNDR | hsa-miR-30b-5p | Subarachnoid hemorrhage traumatic | MNDR-E-MI-37036 |
| MNDR | hsa-miR-30b-5p | Brain injury chronic | MNDR-E-MI-37037 |
| MNDR | hsa-miR-30b-5p | Intracranial hemorrhage hypertensive | MNDR-E-MI-37038 |
| MNDR | hsa-miR-30b-5p | Stroke | MNDR-E-MI-37039 |
| MNDR | hsa-miR-30b-5p | Stroke lacunar | MNDR-E-MI-37040 |
| MNDR | hsa-miR-30b-5p | Barrett's carcinogenesis | MNDR-E-MI-37041 |
| MNDR | hsa-miR-30b-5p | Duke C | MNDR-E-MI-37042 |
RNA Interaction Information
| Resource | RNA Symbol | Species | Link | RNALocate ID |
| RNAInter | AC254633.1 | Homo sapiens | RR00032111 |
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