Basic Information
| RNALocate ID: | RLID:11001558 |
| RNA Symbol: | hsa-miR-223-3p |
| Localization: | Exosome |
RNA Information
| RNA Name: | hsa-miR-223-3p |
| RNA ID: | miRBase:MIMAT0000280 |
| RNA Category: | miRNA |
| Species: | Homo sapiens |
Localization Information
| PubMed ID: | 22211110 |
| Tissue/Cell Line: | Breast milk |
| Method: | Next-generation RNA sequencing |
|
The expression profile of selected miRNAs in breast milk exosomes. Originally published in Int J Biol Sci. Zhou Q, et al, 2012. Reproduced under the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/) |
|
| Description: | Distribution and characterization of miRNAs in breast milk exosomes. (A) Distribution of pre-miRNAs. Out of 1,424 pre-miRNAs deposited in miRBase 17.0 (blue circle), 87 (6.11%) pre-miRNAs have been designated as immune-related pre-miRNAs based on annotation in the Pathway Central database (SABiosciences, MD, USA). Immune-related pre-miRNAs (59 of 452, 13.05%) are enriched in breast milk exosomes (red circle). χ2 test: Number of immune-related miRNAs and others detected in breast milk exosomes compared with the total entries in miRBase 17.0. (B) Top ten most highly expressed unique miRNAs. Plot of the unique miRNAs (starting from the miRNA with the highest counts, x-axis) versus their cumulative % of the total counts from 602 unique miRNAs detected in breast milk exosomes for each small RNA library. Values are means ± s.d. The dashed horizontal line at 62.3% represents the level of the top ten unique miRNAs and the % of individual miRNAs is marked by the gray line. (C-E) The expression profile of selected miRNAs in breast milk exosomes. (C) 59 immune-related pre-miRNAs; (D) miR-17-92 cluster and paralogous clusters, and (E) ten well-characterized tissue-specific pre-miRNAs. Data are collected from Figure 2. |
Other Subcellular Localization
| RNALocate ID | Localization | Tissue/Cell line | PubMed ID |
| RLID:01001680 | Endoplasmic reticulum membrane | Cortical tissue | 32451872 |
| RLID:11001553 | Exosome | Dendritic cells (in vitro differentiated Langerhans cells)|Healthy plasma|Mast cells (HMC-1 cell line)|PCa patient plasma | 25267620 |
| RLID:11001554 | Exosome | Macrophages | 27396686 |
| RLID:11001555 | Exosome | B cell line (Raji)|Primary dendritic cells | 21505438 |
| RLID:11001556 | Exosome | Breast cancer cell lines (HEK-293T|MDA-MB-231|SKBR3)|Macrophages | 21939504 |
| RLID:11001557 | Exosome | Ovarian follicular fluid | 22116803 |
| RLID:11001559 | Exosome | Brain tissue | 23382797 |
| RLID:11001560 | Exosome | Plasma | 23663360 |
| RLID:11001561 | Exosome | Human mast cell line (HMC-1) | 24009880 |
| RLID:11001562 | Exosome | Plasma | 24130905 |
| RLID:11001563 | Exosome | B cell lymphoma cell lines|EBV-transformed lymphoblastoid B cells | 25242326 |
| RLID:11001564 | Exosome | Saliva | 25376581 |
| RLID:11001565 | Microvesicle | Liver resident stem cells|Mesenchymal stem cells | 20668554 |
| RLID:11001566 | Microvesicle | Plasma | 23077538 |
| RLID:11001567 | Microvesicle | Follicular fluid | 23666971 |
| RLID-D:11000065 | Exosome | Blood|Breast milk|Mast cells | |
| RLID-D:11000339 | Microvesicle | Fibroblasts|Mesenchymal stem cells |
ncRNA Disease Information
| Resource | RNA Symbol | Disease | Link |
| MNDR | hsa-miR-223-3p | Inflammatory bowel disease | MNDR-E-MI-31154 |
| MNDR | hsa-miR-223-3p | Splenic marginal zone lymphoma | MNDR-E-MI-31155 |
| MNDR | hsa-miR-223-3p | Multiple sclerosis chronic progressive | MNDR-E-MI-31156 |
| MNDR | hsa-miR-223-3p | Oral squamous cell carcinoma | MNDR-E-MI-31157 |
| MNDR | hsa-miR-223-3p | Medulloblastoma | MNDR-E-MI-31158 |
| MNDR | hsa-miR-223-3p | Small intestinal neuroendocrine tumor | MNDR-E-MI-31159 |
| MNDR | hsa-miR-223-3p | Lymphoma | MNDR-E-MI-31160 |
| MNDR | hsa-miR-223-3p | Lymphoma non-hodgkin | MNDR-E-MI-31161 |
| MNDR | hsa-miR-223-3p | Estrogen-receptor positive breast cancer | MNDR-E-MI-31162 |
| MNDR | hsa-miR-223-3p | Estrogen-receptor negative breast cancer | MNDR-E-MI-31163 |
| MNDR | hsa-miR-223-3p | Progesterone-receptor positive breast cancer | MNDR-E-MI-31164 |
| MNDR | hsa-miR-223-3p | Progesterone-receptor negative breast cancer | MNDR-E-MI-31165 |
| MNDR | hsa-miR-223-3p | Acute promyelocytic leukemia | MNDR-E-MI-31166 |
| MNDR | hsa-miR-223-3p | Breast cancer luminal | MNDR-E-MI-31167 |
| MNDR | hsa-miR-223-3p | Precursor cell lymphoblastic leukemia-lymphoma | MNDR-E-MI-31168 |
| MNDR | hsa-miR-223-3p | Hereditary neutrophilia | MNDR-E-MI-31169 |
| MNDR | hsa-miR-223-3p | Small intestine cancer | MNDR-E-MI-31170 |
| MNDR | hsa-miR-223-3p | Dermatomyositis | MNDR-E-MI-31171 |
| MNDR | hsa-miR-223-3p | Prostate cancer | MNDR-E-MI-31172 |
| MNDR | hsa-miR-223-3p | Chronic lymphocytic leukemia | MNDR-E-MI-31173 |
| MNDR | hsa-miR-223-3p | Gastric cancer | MNDR-E-MI-31174 |
| MNDR | hsa-miR-223-3p | Gastric lymphoma | MNDR-E-MI-31175 |
| MNDR | hsa-miR-223-3p | Alzheimer disease | MNDR-E-MI-31176 |
| MNDR | hsa-miR-223-3p | Intracranial aneurysm | MNDR-E-MI-31177 |
| MNDR | hsa-miR-223-3p | Bladder cancer | MNDR-E-MI-31178 |
| MNDR | hsa-miR-223-3p | Esophageal carcinoma | MNDR-E-MI-31179 |
| MNDR | hsa-miR-223-3p | Sarcoma | MNDR-E-MI-31180 |
| MNDR | hsa-miR-223-3p | Dysautonomia familial | MNDR-E-MI-31181 |
| MNDR | hsa-miR-223-3p | Polycystic ovary syndrome | MNDR-E-MI-31182 |
| MNDR | hsa-miR-223-3p | Duchenne muscular dystrophy | MNDR-E-MI-31183 |
| MNDR | hsa-miR-223-3p | Primary biliary cirrhosis | MNDR-E-MI-31184 |
| MNDR | hsa-miR-223-3p | Leukemia | MNDR-E-MI-31185 |
| MNDR | hsa-miR-223-3p | Huntington disease | MNDR-E-MI-31186 |
| MNDR | hsa-miR-223-3p | Chorea | MNDR-E-MI-31187 |
| MNDR | hsa-miR-223-3p | Cardiovascular disease | MNDR-E-MI-31188 |
| MNDR | hsa-miR-223-3p | Lung cancer | MNDR-E-MI-31189 |
| MNDR | hsa-miR-223-3p | Kawasaki disease | MNDR-E-MI-31190 |
| MNDR | hsa-miR-223-3p | Down syndrome | MNDR-E-MI-31191 |
| MNDR | hsa-miR-223-3p | Parkinson disease | MNDR-E-MI-31192 |
| MNDR | hsa-miR-223-3p | Basal-like breast cancer | MNDR-E-MI-31193 |
| MNDR | hsa-miR-223-3p | Thyroid cancer | MNDR-E-MI-31194 |
| MNDR | hsa-miR-223-3p | Pancreatic cancer | MNDR-E-MI-31195 |
| MNDR | hsa-miR-223-3p | HCV | MNDR-E-MI-31196 |
| MNDR | hsa-miR-223-3p | Melanoma | MNDR-E-MI-31197 |
| MNDR | hsa-miR-223-3p | Rectum adenocarcinoma | MNDR-E-MI-31198 |
| MNDR | hsa-miR-223-3p | Nephroblastoma | MNDR-E-MI-31199 |
| MNDR | hsa-miR-223-3p | Colon cancer | MNDR-E-MI-31200 |
| MNDR | hsa-miR-223-3p | Essential thrombocythemia | MNDR-E-MI-31201 |
| MNDR | hsa-miR-223-3p | Ischemic attack transient | MNDR-E-MI-31202 |
| MNDR | hsa-miR-223-3p | Colon adenocarcinoma | MNDR-E-MI-31203 |
| MNDR | hsa-miR-223-3p | Multiple sclerosis relapsing-remitting | MNDR-E-MI-31204 |
| MNDR | hsa-miR-223-3p | Ovarian cancer | MNDR-E-MI-31205 |
| MNDR | hsa-miR-223-3p | Asthma | MNDR-E-MI-31206 |
| MNDR | hsa-miR-223-3p | Pulmonary tuberculosis | MNDR-E-MI-31207 |
| MNDR | hsa-miR-223-3p | Carcinoma ductal breast | MNDR-E-MI-31208 |
| MNDR | hsa-miR-223-3p | Glioblastoma | MNDR-E-MI-31209 |
| MNDR | hsa-miR-223-3p | Glioma | MNDR-E-MI-31210 |
| MNDR | hsa-miR-223-3p | Nemaline myopathy | MNDR-E-MI-31211 |
| MNDR | hsa-miR-223-3p | Amyotrophic lateral sclerosis | MNDR-E-MI-31212 |
| MNDR | hsa-miR-223-3p | Epilepsy temporal lobe | MNDR-E-MI-31213 |
| MNDR | hsa-miR-223-3p | Osteosarcoma | MNDR-E-MI-31214 |
| MNDR | hsa-miR-223-3p | Liposarcoma | MNDR-E-MI-31215 |
| MNDR | hsa-miR-223-3p | Coronary artery disease | MNDR-E-MI-31216 |
| MNDR | hsa-miR-223-3p | Inclusion body myositis | MNDR-E-MI-31217 |
| MNDR | hsa-miR-223-3p | Pancreatic ductal adenocarcinoma | MNDR-E-MI-31218 |
| MNDR | hsa-miR-223-3p | Meningioma | MNDR-E-MI-31219 |
| MNDR | hsa-miR-223-3p | Liver cancer | MNDR-E-MI-31220 |
| MNDR | hsa-miR-223-3p | Uterine cancer | MNDR-E-MI-31221 |
| MNDR | hsa-miR-223-3p | Cervical adenocarcinoma | MNDR-E-MI-31222 |
| MNDR | hsa-miR-223-3p | Gastric adenocarcinoma | MNDR-E-MI-31223 |
| MNDR | hsa-miR-223-3p | Pituitary adenoma | MNDR-E-MI-31224 |
| MNDR | hsa-miR-223-3p | Lung squamous cell carcinoma | MNDR-E-MI-31225 |
| MNDR | hsa-miR-223-3p | Lung adenocarcinoma | MNDR-E-MI-31226 |
| MNDR | hsa-miR-223-3p | Thyroid carcinoma | MNDR-E-MI-31227 |
| MNDR | hsa-miR-223-3p | Bladder urothelial carcinoma | MNDR-E-MI-31228 |
| MNDR | hsa-miR-223-3p | Pancreatic adenocarcinoma | MNDR-E-MI-31229 |
| MNDR | hsa-miR-223-3p | Carcinoma renal cell | MNDR-E-MI-31230 |
| MNDR | hsa-miR-223-3p | Kidney renal papillary cell carcinoma | MNDR-E-MI-31231 |
| MNDR | hsa-miR-223-3p | Clear cell renal cell carcinoma | MNDR-E-MI-31232 |
| MNDR | hsa-miR-223-3p | Biliary tract cancer | MNDR-E-MI-31233 |
| MNDR | hsa-miR-223-3p | Myelofibrosis | MNDR-E-MI-31234 |
| MNDR | hsa-miR-223-3p | Esophageal cancer | MNDR-E-MI-31235 |
| MNDR | hsa-miR-223-3p | Liver cirrhosis | MNDR-E-MI-31236 |
| MNDR | hsa-miR-223-3p | HIV | MNDR-E-MI-31237 |
| MNDR | hsa-miR-223-3p | Lung small cell carcinoma | MNDR-E-MI-31238 |
| MNDR | hsa-miR-223-3p | Head and neck squamous cell carcinoma | MNDR-E-MI-31239 |
| MNDR | hsa-miR-223-3p | Fibromyalgia | MNDR-E-MI-31240 |
| MNDR | hsa-miR-223-3p | Breast invasive carcinoma | MNDR-E-MI-31241 |
| MNDR | hsa-miR-223-3p | Juvenile rheumatoid arthritis | MNDR-E-MI-31242 |
| MNDR | hsa-miR-223-3p | Hepatocellular carcinoma | MNDR-E-MI-31243 |
| MNDR | hsa-miR-223-3p | Embryonal cancer | MNDR-E-MI-31244 |
| MNDR | hsa-miR-223-3p | B-cell lymphoma | MNDR-E-MI-31245 |
| MNDR | hsa-miR-223-3p | Rheumatoid arthritis | MNDR-E-MI-31246 |
| MNDR | hsa-miR-223-3p | T-cell leukemia | MNDR-E-MI-31247 |
| MNDR | hsa-miR-223-3p | Malignant pleural mesothelioma | MNDR-E-MI-31248 |
| MNDR | hsa-miR-223-3p | Chronic kidney disease | MNDR-E-MI-31249 |
| MNDR | hsa-miR-223-3p | Periodontitis | MNDR-E-MI-31250 |
| MNDR | hsa-miR-223-3p | Chronic fatigue syndrome | MNDR-E-MI-31251 |
| MNDR | hsa-miR-223-3p | Chronic myeloid leukemia | MNDR-E-MI-31252 |
| MNDR | hsa-miR-223-3p | Hodgkin lymphoma | MNDR-E-MI-31253 |
| MNDR | hsa-miR-223-3p | Burkitt lymphoma | MNDR-E-MI-31254 |
| MNDR | hsa-miR-223-3p | Dementia vascular | MNDR-E-MI-31255 |
| MNDR | hsa-miR-223-3p | Neuromyelitis optica | MNDR-E-MI-31256 |
| MNDR | hsa-miR-223-3p | Psoriasis | MNDR-E-MI-31257 |
| MNDR | hsa-miR-223-3p | Skin cutaneous melanoma | MNDR-E-MI-31258 |
| MNDR | hsa-miR-223-3p | Skin melanoma | MNDR-E-MI-31259 |
| MNDR | hsa-miR-223-3p | Acute myelocytic leukemia | MNDR-E-MI-31260 |
| MNDR | hsa-miR-223-3p | Colorectal cancer | MNDR-E-MI-31261 |
| MNDR | hsa-miR-223-3p | Multiple myeloma | MNDR-E-MI-31262 |
| MNDR | hsa-miR-223-3p | Acute lymphocytic leukemia | MNDR-E-MI-31263 |
| MNDR | hsa-miR-223-3p | Esophageal squamous cell carcinoma | MNDR-E-MI-31264 |
| MNDR | hsa-miR-223-3p | Nasopharyngeal cancer | MNDR-E-MI-31265 |
| MNDR | hsa-miR-223-3p | Chronic kidney disease-mineral and bone disorder | MNDR-E-MI-31266 |
| MNDR | hsa-miR-223-3p | Epstein-barr virus infections | MNDR-E-MI-31267 |
| MNDR | hsa-miR-223-3p | Subarachnoid hemorrhage traumatic | MNDR-E-MI-31268 |
| MNDR | hsa-miR-223-3p | Sarcopenia | MNDR-E-MI-31269 |
| MNDR | hsa-miR-223-3p | Stroke lacunar | MNDR-E-MI-31270 |
RNA Interaction Information
| Resource | RNA Symbol | Species | Link | RNALocate ID |
| RNAInter | ABCB1 | Homo sapiens | RR00022781 |
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