Basic Information
RNALocate ID: RLID:11000745
RNA Symbol: hsa-miR-20a-5p
Localization: Exosome
RNA Information
RNA Name: hsa-miR-20a-5p
RNA ID: miRBase:MIMAT0000075
RNA Category: miRNA
Species: Homo sapiens
Sequence:
Localization Information
PubMed ID: 25349172
Tissue/Cell Line: Serum
Method: Next-generation RNA sequencing

Originally published in Mol Psychiatry. Cheng L, et al, 2015. Reproduced under the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/)
Description: Deep sequencing of the exosomal RNA extracted from serum samples was performed and sequences were mapped to miRBase Exosomal miRNA biomarkers for Alzheimer's disease. Approximately half of the reads obtained (43%) from small RNA sequencing corresponded with miRNA sequences (Supplementary Table 1). Overall, the sample cohort mapped to 1419 known human miRNA sequences (Supplementary Table 2). Following normalisation of reads and performing ANOVA analyses, 17 miRNA were found to be significantly deregulated (Figure 1); 14 miRNA were found to be upregulated (hsa-miR-361-5p, hsa-miR-30e-5p, hsa-miR-93-5p, hsa-miR-15a-5p, hsa-miR-143-3p, hsa-miR-335-5p, hsa-miR-106b-5p, hsa-miR-101-3p, hsa-miR-424-5p, hsa-miR-106a-5p, hsa-miR-18b-5p, hsa-miR-3065-5p, hsa-miR-20a-5p and hsa-miR-582-5p) and three miRNA were found to be downregulated (hsa-miR-1306-5p, hsa-miR-342-3p and 15b-3p; Table 2). Data are collected from Table 2.
Other Subcellular Localization
RNALocate ID Localization Tissue/Cell line PubMed ID
RLID:01001294 Cytoplasm Neural progenitor cells 21363885
RLID:01001295 Cytoplasm Cell line (HeLa) 21695135
RLID:01001296 Cytoplasm HeLa cells 23940654
RLID:01001297 Cytoplasm Breast adenocarcinoma cells (MCF-7)|Cervical adenocarcinoma cells (HeLa) 24918059
RLID:01001298 Mitochondrion Myotube 27396686
RLID:01001299 Mitochondrion Skeletal muscle cells 27563705
RLID:01001300 Mitochondrion Skeletal muscle myoblasts 21637849
RLID:01001301 Mitochondrion Cell line (HEK-293|HeLa) 22984580
RLID:01001302 Nucleus Breast adenocarcinoma cells (MCF-7)|Cervical adenocarcinoma cells (HeLa) 24918059
RLID:01001303 Nucleolus Breast adenocarcinoma cells (MCF-7) 24918059
RLID:01001304 Nucleus Colon adenocarcinoma cells 20864815
RLID:11000737 Exosome Sera 24978137
RLID:11000738 Exosome Human cervical carcinoma cell line (HeLa|SiHa) 25760330
RLID:11000739 Exosome Glioblastoma cells 19011622
RLID:11000740 Exosome Primary dendritic cells|T cell line (J77) 21505438
RLID:11000741 Exosome Breast milk 22211110
RLID:11000742 Exosome Brain tissue 23382797
RLID:11000743 Exosome Plasma 23663360
RLID:11000744 Exosome Human mast cell line (HMC-1) 24009880
RLID:11000746 Exosome Cerebrospinal fluid 25420022
RLID:11000747 Extracellular Vesicle Liposarcoma cell lines (Lipo246|Lipo863|LPS141)|Preadipocytes 28588009
RLID:11000748 Extracellular vesicle HEK-293T cells 22849433
RLID:11000749 Microvesicle Glioblastoma cells 19011622
RLID:11000750 Microvesicle Seminal plasma 23539611
RLID:11000751 Microvesicle Hepatoma cells 23771658
RLID-D:11000012 Exosome B lymphoblastoid cells|Chronic lymphocytic leukemia cells|Endothelial cells|Epithelial cells|Lymphoma tissue|Tongue tissue
RLID-D:11000274 Microvesicle Colon cancer cell line (LIM1863)|Fibroblasts|Mesenchymal stem cells|Urine
ncRNA Disease Information
Resource RNA Symbol Disease Link
MNDR hsa-miR-20a-5p Splenic marginal zone lymphoma MNDR-E-MI-27697
MNDR hsa-miR-20a-5p Multiple sclerosis chronic progressive MNDR-E-MI-27698
MNDR hsa-miR-20a-5p Colorectal adenocarcinoma MNDR-E-MI-27699
MNDR hsa-miR-20a-5p Oral squamous cell carcinoma MNDR-E-MI-27700
MNDR hsa-miR-20a-5p Large cell neuroendocrine cancer MNDR-E-MI-27701
MNDR hsa-miR-20a-5p Medulloblastoma MNDR-E-MI-27702
MNDR hsa-miR-20a-5p B cell lymphoma of malt type MNDR-E-MI-27703
MNDR hsa-miR-20a-5p High-grade serous ovarian carcinoma MNDR-E-MI-27704
MNDR hsa-miR-20a-5p Autism spectrum disorder MNDR-E-MI-27705
MNDR hsa-miR-20a-5p Lymphoma MNDR-E-MI-27706
MNDR hsa-miR-20a-5p Lymphoma non-hodgkin MNDR-E-MI-27707
MNDR hsa-miR-20a-5p Estrogen-receptor positive breast cancer MNDR-E-MI-27708
MNDR hsa-miR-20a-5p Estrogen-receptor negative breast cancer MNDR-E-MI-27709
MNDR hsa-miR-20a-5p Progesterone-receptor positive breast cancer MNDR-E-MI-27710
MNDR hsa-miR-20a-5p Progesterone-receptor negative breast cancer MNDR-E-MI-27711
MNDR hsa-miR-20a-5p Her2-receptor positive breast cancer MNDR-E-MI-27712
MNDR hsa-miR-20a-5p Breast cancer luminal MNDR-E-MI-27713
MNDR hsa-miR-20a-5p Niemann-pick disease type c MNDR-E-MI-27714
MNDR hsa-miR-20a-5p Precursor cell lymphoblastic leukemia-lymphoma MNDR-E-MI-27715
MNDR hsa-miR-20a-5p B cell acute lymphoblastic leukemia MNDR-E-MI-27716
MNDR hsa-miR-20a-5p Dermatomyositis MNDR-E-MI-27717
MNDR hsa-miR-20a-5p Prostate cancer MNDR-E-MI-27718
MNDR hsa-miR-20a-5p Gastric cancer MNDR-E-MI-27719
MNDR hsa-miR-20a-5p Gastric lymphoma MNDR-E-MI-27720
MNDR hsa-miR-20a-5p Alzheimer disease MNDR-E-MI-27721
MNDR hsa-miR-20a-5p Intracranial aneurysm MNDR-E-MI-27722
MNDR hsa-miR-20a-5p Bladder cancer MNDR-E-MI-27723
MNDR hsa-miR-20a-5p Esophageal carcinoma MNDR-E-MI-27724
MNDR hsa-miR-20a-5p Dysautonomia familial MNDR-E-MI-27725
MNDR hsa-miR-20a-5p Primary biliary cirrhosis MNDR-E-MI-27726
MNDR hsa-miR-20a-5p Leukemia MNDR-E-MI-27727
MNDR hsa-miR-20a-5p Ataxia telangiectasia MNDR-E-MI-27728
MNDR hsa-miR-20a-5p Huntington disease MNDR-E-MI-27729
MNDR hsa-miR-20a-5p Chorea MNDR-E-MI-27730
MNDR hsa-miR-20a-5p Cardiovascular disease MNDR-E-MI-27731
MNDR hsa-miR-20a-5p Carotid stenosis MNDR-E-MI-27732
MNDR hsa-miR-20a-5p Moyamoya disease MNDR-E-MI-27733
MNDR hsa-miR-20a-5p Lung cancer MNDR-E-MI-27734
MNDR hsa-miR-20a-5p Down syndrome MNDR-E-MI-27735
MNDR hsa-miR-20a-5p Parkinson disease MNDR-E-MI-27736
MNDR hsa-miR-20a-5p Niemann-pick disease MNDR-E-MI-27737
MNDR hsa-miR-20a-5p Colon carcinoma MNDR-E-MI-27738
MNDR hsa-miR-20a-5p Basal-like breast cancer MNDR-E-MI-27739
MNDR hsa-miR-20a-5p Squamous cell carcinoma MNDR-E-MI-27740
MNDR hsa-miR-20a-5p Thyroid cancer MNDR-E-MI-27741
MNDR hsa-miR-20a-5p Pituitary neoplasms MNDR-E-MI-27742
MNDR hsa-miR-20a-5p Pancreatic cancer MNDR-E-MI-27743
MNDR hsa-miR-20a-5p Melanoma MNDR-E-MI-27744
MNDR hsa-miR-20a-5p Lesch-nyhan syndrome MNDR-E-MI-27745
MNDR hsa-miR-20a-5p Rectum adenocarcinoma MNDR-E-MI-27746
MNDR hsa-miR-20a-5p Nephroblastoma MNDR-E-MI-27747
MNDR hsa-miR-20a-5p Colon cancer MNDR-E-MI-27748
MNDR hsa-miR-20a-5p Ischemic attack transient MNDR-E-MI-27749
MNDR hsa-miR-20a-5p Colon adenocarcinoma MNDR-E-MI-27750
MNDR hsa-miR-20a-5p Multiple sclerosis MNDR-E-MI-27751
MNDR hsa-miR-20a-5p Multiple sclerosis relapsing-remitting MNDR-E-MI-27752
MNDR hsa-miR-20a-5p Ovarian cancer MNDR-E-MI-27753
MNDR hsa-miR-20a-5p Prostate adenocarcinoma MNDR-E-MI-27754
MNDR hsa-miR-20a-5p Kidney cancer MNDR-E-MI-27755
MNDR hsa-miR-20a-5p Endometriosis MNDR-E-MI-27756
MNDR hsa-miR-20a-5p Carcinoma ductal breast MNDR-E-MI-27757
MNDR hsa-miR-20a-5p Glioblastoma MNDR-E-MI-27758
MNDR hsa-miR-20a-5p Astrocytoma MNDR-E-MI-27759
MNDR hsa-miR-20a-5p Glioma MNDR-E-MI-27760
MNDR hsa-miR-20a-5p Oligodendroglioma MNDR-E-MI-27761
MNDR hsa-miR-20a-5p Central nervous system lymphoma MNDR-E-MI-27762
MNDR hsa-miR-20a-5p Chordoma MNDR-E-MI-27763
MNDR hsa-miR-20a-5p Amyotrophic lateral sclerosis MNDR-E-MI-27764
MNDR hsa-miR-20a-5p Epilepsy temporal lobe MNDR-E-MI-27765
MNDR hsa-miR-20a-5p Osteosarcoma MNDR-E-MI-27766
MNDR hsa-miR-20a-5p Liposarcoma MNDR-E-MI-27767
MNDR hsa-miR-20a-5p Meningioma MNDR-E-MI-27768
MNDR hsa-miR-20a-5p Liver cancer MNDR-E-MI-27769
MNDR hsa-miR-20a-5p Uterine cancer MNDR-E-MI-27770
MNDR hsa-miR-20a-5p Gastric adenocarcinoma MNDR-E-MI-27771
MNDR hsa-miR-20a-5p Pituitary adenoma MNDR-E-MI-27772
MNDR hsa-miR-20a-5p Lung squamous cell carcinoma MNDR-E-MI-27773
MNDR hsa-miR-20a-5p Carcinoma lung non-small-cell MNDR-E-MI-27774
MNDR hsa-miR-20a-5p Lung adenocarcinoma MNDR-E-MI-27775
MNDR hsa-miR-20a-5p Adrenocortical carcinoma MNDR-E-MI-27776
MNDR hsa-miR-20a-5p Thyroid carcinoma MNDR-E-MI-27777
MNDR hsa-miR-20a-5p Ovarian carcinoma MNDR-E-MI-27778
MNDR hsa-miR-20a-5p Bladder urothelial carcinoma MNDR-E-MI-27779
MNDR hsa-miR-20a-5p Pancreatic adenocarcinoma MNDR-E-MI-27780
MNDR hsa-miR-20a-5p Brain stem cancer MNDR-E-MI-27781
MNDR hsa-miR-20a-5p Cervical cancer MNDR-E-MI-27782
MNDR hsa-miR-20a-5p Myasthenia gravis autoimmune experimental MNDR-E-MI-27783
MNDR hsa-miR-20a-5p Kidney renal clear cell carcinoma MNDR-E-MI-27784
MNDR hsa-miR-20a-5p Kidney renal papillary cell carcinoma MNDR-E-MI-27785
MNDR hsa-miR-20a-5p Clear cell renal cell carcinoma MNDR-E-MI-27786
MNDR hsa-miR-20a-5p Biliary tract cancer MNDR-E-MI-27787
MNDR hsa-miR-20a-5p Pancreatic carcinoma MNDR-E-MI-27788
MNDR hsa-miR-20a-5p Cholangiocarcinoma MNDR-E-MI-27789
MNDR hsa-miR-20a-5p Esophageal cancer MNDR-E-MI-27790
MNDR hsa-miR-20a-5p Lung small cell carcinoma MNDR-E-MI-27791
MNDR hsa-miR-20a-5p Head and neck squamous cell carcinoma MNDR-E-MI-27792
MNDR hsa-miR-20a-5p T acute lymphoblastic leukemia MNDR-E-MI-27793
MNDR hsa-miR-20a-5p Acute t cell leukemia MNDR-E-MI-27794
MNDR hsa-miR-20a-5p Pulmonary hypertension MNDR-E-MI-27795
MNDR hsa-miR-20a-5p Adenoma MNDR-E-MI-27796
MNDR hsa-miR-20a-5p Breast invasive carcinoma MNDR-E-MI-27797
MNDR hsa-miR-20a-5p Early hepatocellular carcinoma MNDR-E-MI-27798
MNDR hsa-miR-20a-5p B-cell lymphoma MNDR-E-MI-27799
MNDR hsa-miR-20a-5p Rheumatoid arthritis MNDR-E-MI-27800
MNDR hsa-miR-20a-5p T-cell leukemia MNDR-E-MI-27801
MNDR hsa-miR-20a-5p Retinoblastoma MNDR-E-MI-27802
MNDR hsa-miR-20a-5p Neuroblastoma MNDR-E-MI-27803
MNDR hsa-miR-20a-5p Chronic myeloid leukemia MNDR-E-MI-27804
MNDR hsa-miR-20a-5p Hodgkin disease MNDR-E-MI-27805
MNDR hsa-miR-20a-5p Burkitt lymphoma MNDR-E-MI-27806
MNDR hsa-miR-20a-5p Lymphosarcoma MNDR-E-MI-27807
MNDR hsa-miR-20a-5p Neuromyelitis optica MNDR-E-MI-27808
MNDR hsa-miR-20a-5p Psoriasis MNDR-E-MI-27809
MNDR hsa-miR-20a-5p Acute myelogenous leukemia MNDR-E-MI-27810
MNDR hsa-miR-20a-5p Colorectal cancer MNDR-E-MI-27811
MNDR hsa-miR-20a-5p Multiple myeloma MNDR-E-MI-27812
MNDR hsa-miR-20a-5p Acute lymphocytic leukemia MNDR-E-MI-27813
MNDR hsa-miR-20a-5p Uterine cervical neoplasms MNDR-E-MI-27814
MNDR hsa-miR-20a-5p Ependymoma MNDR-E-MI-27815
MNDR hsa-miR-20a-5p Nasopharyngeal cancer MNDR-E-MI-27816
MNDR hsa-miR-20a-5p Prostatic neoplasms MNDR-E-MI-27817
MNDR hsa-miR-20a-5p Pseudorabies MNDR-E-MI-27818
MNDR hsa-miR-20a-5p Arsenic poisoning MNDR-E-MI-27819
MNDR hsa-miR-20a-5p Stroke lacunar MNDR-E-MI-27820
MNDR hsa-miR-20a-5p Duke C MNDR-E-MI-27821
MNDR hsa-miR-20a-5p High grade dysplastic nodule MNDR-E-MI-27822
MNDR hsa-miR-20a-5p Tubulovillous adenoma MNDR-E-MI-27823
RNA Interaction Information
Resource RNA Symbol Species Link RNALocate ID
RNAInter ABL2 Homo sapiens RR00027165
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