Basic Information
| RNALocate ID: | RLID:11000643 |
| RNA Symbol: | hsa-let-7f-5p |
| Localization: | Exosome |
RNA Information
| RNA Name: | hsa-let-7f |
| RNA ID: | miRBase:MIMAT0000067 |
| RNA Category: | miRNA |
| Species: | Homo sapiens |
Localization Information
| PubMed ID: | 20976003 |
| Tissue/Cell Line: | Breast cancer cell line (MCF-7) |
| Method: | Microarray |
| Description: | Because of the suggested roles of extracellular miRNAs in signaling and diagnosis, we investigated whether the intracellular and extracellular miRNA composition are the same. To answer this question, we performed microRNA microarray analyses of MCF7 cellular (c) and extracellular (x) RNAs (Figure 2A), and found that about 66% of the released miRNAs are at an abundance that closely reflects the cellular miRNA abundance (Figures 2B and 2C). This finding is in agreement with a model wherein most, but not all miRNAs are released passively by mass action. Data are collected from Figure 2. |
Other Subcellular Localization
| RNALocate ID | Localization | Tissue/Cell line | PubMed ID |
| RLID:01001241 | Cytoplasm | Nasopharyngeal carcinoma cells | 20498841 |
| RLID:01001242 | Cytoplasm | Breast adenocarcinoma cells (MCF-7)|Cervical adenocarcinoma cells (HeLa) | 24918059 |
| RLID:01001243 | Mitochondrion | Skeletal muscle myoblasts | 21637849 |
| RLID:01001244 | Mitochondrion | Cell line (HEK-293|HeLa) | 22984580 |
| RLID:01001245 | Nucleus | Breast adenocarcinoma cells (MCF-7)|Cervical adenocarcinoma cells (HeLa) | 24918059 |
| RLID:01001246 | Nucleolus | Breast adenocarcinoma cells (MCF-7)|Cervical adenocarcinoma cells (HeLa) | 24918059 |
| RLID:01001247 | Nucleus | Nasopharyngeal carcinoma cells | 20498841 |
| RLID:01001248 | Nucleus | Colon adenocarcinoma cells | 20864815 |
| RLID:11000640 | Exosome | Human cervical cancer cell line (HeLa) | 25760330 |
| RLID:11000641 | Exosome | Human milk | 28688106 |
| RLID:11000642 | Exosome | Hetastatic gastric cancer cell line (AZ-P7a) | 20949044 |
| RLID:11000644 | Exosome | Primary dendritic cells|T cell line (J77) | 21505438 |
| RLID:11000645 | Exosome | Renal cancer cells | 21670082 |
| RLID:11000646 | Exosome | Brain tissue | 23382797 |
| RLID:11000647 | Exosome | Plasma | 23663360 |
| RLID:11000648 | Exosome | Human mast cell line (HMC-1) | 24009880 |
| RLID:11000649 | Exosome | Breast cancer cell lines (MCF-7|MDA-MB-231) | 24468161 |
| RLID:11000650 | Exosome | Plasma | 24937531 |
| RLID:11000651 | Exosome | Human esophageal cancer cell line (EC9706) | 25184951 |
| RLID:11000652 | Microvesicle | Plasma | 23077538 |
| RLID:11000653 | Microvesicle | Seminal plasma | 23539611 |
| RLID:11000654 | Microvesicle | Hepatoma cells | 23771658 |
| RLID-D:11000006 | Exosome | Blood|B lymphoblastoid cells|Breast milk|Colon tissue|Endothelial cells|Epithelial cells|Lymphoma tissue|Mast cells|Seminal fluid|Tongue tissue | |
| RLID-D:11000266 | Microvesicle | Blood|Breast cell line|Colon cancer cell line (LIM1863)|Fibroblasts|Mesenchymal stem cells|Urine |
ncRNA Disease Information
| Resource | RNA Symbol | Disease | Link |
| MNDR | hsa-let-7f-5p | Splenic marginal zone lymphoma | MNDR-E-MI-01758 |
| MNDR | hsa-let-7f-5p | Multiple sclerosis chronic progressive | MNDR-E-MI-01759 |
| MNDR | hsa-let-7f-5p | Oral squamous cell carcinoma | MNDR-E-MI-01760 |
| MNDR | hsa-let-7f-5p | B cell lymphoma of malt type | MNDR-E-MI-01761 |
| MNDR | hsa-let-7f-5p | Ovarian clear cell carcinoma | MNDR-E-MI-01762 |
| MNDR | hsa-let-7f-5p | Lymphoma | MNDR-E-MI-01763 |
| MNDR | hsa-let-7f-5p | Lymphoma non-hodgkin | MNDR-E-MI-01764 |
| MNDR | hsa-let-7f-5p | Estrogen-receptor positive breast cancer | MNDR-E-MI-01765 |
| MNDR | hsa-let-7f-5p | Estrogen-receptor negative breast cancer | MNDR-E-MI-01766 |
| MNDR | hsa-let-7f-5p | Progesterone-receptor positive breast cancer | MNDR-E-MI-01767 |
| MNDR | hsa-let-7f-5p | Progesterone-receptor negative breast cancer | MNDR-E-MI-01768 |
| MNDR | hsa-let-7f-5p | Her2-receptor positive breast cancer | MNDR-E-MI-01769 |
| MNDR | hsa-let-7f-5p | Breast cancer luminal | MNDR-E-MI-01770 |
| MNDR | hsa-let-7f-5p | Dermatomyositis | MNDR-E-MI-01771 |
| MNDR | hsa-let-7f-5p | Prostate cancer | MNDR-E-MI-01772 |
| MNDR | hsa-let-7f-5p | Gastric cancer | MNDR-E-MI-01773 |
| MNDR | hsa-let-7f-5p | Gastric lymphoma | MNDR-E-MI-01774 |
| MNDR | hsa-let-7f-5p | Alzheimer disease | MNDR-E-MI-01775 |
| MNDR | hsa-let-7f-5p | Intracranial aneurysm | MNDR-E-MI-01776 |
| MNDR | hsa-let-7f-5p | Dysautonomia familial | MNDR-E-MI-01777 |
| MNDR | hsa-let-7f-5p | Malaria | MNDR-E-MI-01778 |
| MNDR | hsa-let-7f-5p | Cardiovascular disease | MNDR-E-MI-01779 |
| MNDR | hsa-let-7f-5p | Lung cancer | MNDR-E-MI-01780 |
| MNDR | hsa-let-7f-5p | Metabolic syndrome x | MNDR-E-MI-01781 |
| MNDR | hsa-let-7f-5p | Parkinson disease | MNDR-E-MI-01782 |
| MNDR | hsa-let-7f-5p | Machado-joseph disease | MNDR-E-MI-01783 |
| MNDR | hsa-let-7f-5p | Niemann-pick disease | MNDR-E-MI-01784 |
| MNDR | hsa-let-7f-5p | Breast cancer | MNDR-E-MI-01785 |
| MNDR | hsa-let-7f-5p | Thyroid cancer | MNDR-E-MI-01786 |
| MNDR | hsa-let-7f-5p | Pancreatic cancer | MNDR-E-MI-01787 |
| MNDR | hsa-let-7f-5p | Melanoma | MNDR-E-MI-01788 |
| MNDR | hsa-let-7f-5p | Lesch-nyhan syndrome | MNDR-E-MI-01789 |
| MNDR | hsa-let-7f-5p | Rectum adenocarcinoma | MNDR-E-MI-01790 |
| MNDR | hsa-let-7f-5p | Nephroblastoma | MNDR-E-MI-01791 |
| MNDR | hsa-let-7f-5p | Colon cancer | MNDR-E-MI-01792 |
| MNDR | hsa-let-7f-5p | Colon adenocarcinoma | MNDR-E-MI-01793 |
| MNDR | hsa-let-7f-5p | Multiple sclerosis relapsing-remitting | MNDR-E-MI-01794 |
| MNDR | hsa-let-7f-5p | Familial ovarian cancer | MNDR-E-MI-01795 |
| MNDR | hsa-let-7f-5p | Prostate adenocarcinoma | MNDR-E-MI-01796 |
| MNDR | hsa-let-7f-5p | Endometriosis | MNDR-E-MI-01797 |
| MNDR | hsa-let-7f-5p | Glioblastoma | MNDR-E-MI-01798 |
| MNDR | hsa-let-7f-5p | Glioma | MNDR-E-MI-01799 |
| MNDR | hsa-let-7f-5p | Amyotrophic lateral sclerosis | MNDR-E-MI-01800 |
| MNDR | hsa-let-7f-5p | Temporal lobe epilepsy | MNDR-E-MI-01801 |
| MNDR | hsa-let-7f-5p | Osteosarcoma | MNDR-E-MI-01802 |
| MNDR | hsa-let-7f-5p | Liposarcoma | MNDR-E-MI-01803 |
| MNDR | hsa-let-7f-5p | Inclusion body myositis | MNDR-E-MI-01804 |
| MNDR | hsa-let-7f-5p | Liver cancer | MNDR-E-MI-01805 |
| MNDR | hsa-let-7f-5p | Gastric adenocarcinoma | MNDR-E-MI-01806 |
| MNDR | hsa-let-7f-5p | Lung squamous cell carcinoma | MNDR-E-MI-01807 |
| MNDR | hsa-let-7f-5p | Non-small cell lung adenocarcinoma | MNDR-E-MI-01808 |
| MNDR | hsa-let-7f-5p | Lung adenocarcinoma | MNDR-E-MI-01809 |
| MNDR | hsa-let-7f-5p | Adrenocortical cancer | MNDR-E-MI-01810 |
| MNDR | hsa-let-7f-5p | Papillary thyroid carcinoma | MNDR-E-MI-01811 |
| MNDR | hsa-let-7f-5p | Tuberculosis | MNDR-E-MI-01812 |
| MNDR | hsa-let-7f-5p | Myasthenia gravis | MNDR-E-MI-01813 |
| MNDR | hsa-let-7f-5p | Myasthenia gravis autoimmune experimental | MNDR-E-MI-01814 |
| MNDR | hsa-let-7f-5p | Kidney renal clear cell carcinoma | MNDR-E-MI-01815 |
| MNDR | hsa-let-7f-5p | Kidney renal papillary cell carcinoma | MNDR-E-MI-01816 |
| MNDR | hsa-let-7f-5p | Renal clear cell carcinoma | MNDR-E-MI-01817 |
| MNDR | hsa-let-7f-5p | Biliary tract cancer | MNDR-E-MI-01818 |
| MNDR | hsa-let-7f-5p | Cholangiocarcinoma | MNDR-E-MI-01819 |
| MNDR | hsa-let-7f-5p | Esophageal cancer | MNDR-E-MI-01820 |
| MNDR | hsa-let-7f-5p | Encephalomyelitis | MNDR-E-MI-01821 |
| MNDR | hsa-let-7f-5p | Early hepatocellular carcinoma | MNDR-E-MI-01822 |
| MNDR | hsa-let-7f-5p | Embryonal cancer | MNDR-E-MI-01823 |
| MNDR | hsa-let-7f-5p | Familiar ovarian carcinoma | MNDR-E-MI-01824 |
| MNDR | hsa-let-7f-5p | B-cell lymphoma | MNDR-E-MI-01825 |
| MNDR | hsa-let-7f-5p | Rheumatoid arthritis | MNDR-E-MI-01826 |
| MNDR | hsa-let-7f-5p | T-cell leukemia | MNDR-E-MI-01827 |
| MNDR | hsa-let-7f-5p | Retinoblastoma | MNDR-E-MI-01828 |
| MNDR | hsa-let-7f-5p | Neuroblastoma | MNDR-E-MI-01829 |
| MNDR | hsa-let-7f-5p | Hodgkin lymphoma | MNDR-E-MI-01830 |
| MNDR | hsa-let-7f-5p | Ulcerative colitis | MNDR-E-MI-01831 |
| MNDR | hsa-let-7f-5p | Burkitt lymphoma | MNDR-E-MI-01832 |
| MNDR | hsa-let-7f-5p | Neuromyelitis optica | MNDR-E-MI-01833 |
| MNDR | hsa-let-7f-5p | Acute myelogenous leukemia | MNDR-E-MI-01834 |
| MNDR | hsa-let-7f-5p | Colorectal cancer | MNDR-E-MI-01835 |
| MNDR | hsa-let-7f-5p | Nasopharynx carcinoma | MNDR-E-MI-01836 |
| MNDR | hsa-let-7f-5p | Multiple myeloma | MNDR-E-MI-01837 |
| MNDR | hsa-let-7f-5p | Nasopharyngeal cancer | MNDR-E-MI-01838 |
| MNDR | hsa-let-7f-5p | Prostatic neoplasms | MNDR-E-MI-01839 |
| MNDR | hsa-let-7f-5p | Pseudorabies | MNDR-E-MI-01840 |
| MNDR | hsa-let-7f-5p | Cerebral hemorrhage traumatic | MNDR-E-MI-01841 |
| MNDR | hsa-let-7f-5p | Intracranial hemorrhage hypertensive | MNDR-E-MI-01842 |
| MNDR | hsa-let-7f-5p | Sarcopenia | MNDR-E-MI-01843 |
| MNDR | hsa-let-7f-5p | Stroke lacunar | MNDR-E-MI-01844 |
| MNDR | hsa-let-7f-5p | High grade dysplastic nodule | MNDR-E-MI-01845 |
RNA Interaction Information
| Resource | RNA Symbol | Species | Link | RNALocate ID |
| RNAInter | ABCC5 | Homo sapiens | RR00023749 |
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