Basic Information
| RNALocate ID: | RLID:11000600 |
| RNA Symbol: | hsa-let-7c-5p |
| Localization: | Exosome |
RNA Information
| RNA Name: | hsa-let-7c |
| RNA ID: | miRBase:MIMAT0000064 |
| RNA Category: | miRNA |
| Species: | Homo sapiens |
Localization Information
| PubMed ID: | 23056502 |
| Tissue/Cell Line: | Malignant melanoma cell line (A375) |
| Method: | Microarray |
| Description: | To distinguish miRNA signatures between melanoma cell-derived exosomes and normal melanocyte-derived exosomes, we compared the miRNome in A375 and HEMa-LP exosomes. We identified 130 miRNAs upregulated and 98 miRNAs downregulated in A375 versus HEMa-LP exosomes (Table S6). Data are collected from table S6. |
Other Subcellular Localization
| RNALocate ID | Localization | Tissue/Cell line | PubMed ID |
| RLID:01001208 | Cytoplasm | Nasopharyngeal carcinoma cells | 20498841 |
| RLID:01001209 | Cytoplasm | Cell line (HeLa) | 21695135 |
| RLID:01001210 | Cytoplasm | HeLa cells | 22058130 |
| RLID:01001211 | Cytoplasm | Breast adenocarcinoma cells (MCF-7)|Cervical adenocarcinoma cells (HeLa) | 24918059 |
| RLID:01001212 | Mitochondrion | Skeletal muscle myoblasts | 21637849 |
| RLID:01001213 | Mitochondrion | Cell line (HEK-293|HeLa) | 22984580 |
| RLID:01001214 | Nucleus | Breast adenocarcinoma cells (MCF-7)|Cervical adenocarcinoma cells (HeLa) | 24918059 |
| RLID:01001215 | Nucleolus | Breast adenocarcinoma cells (MCF-7)|Cervical adenocarcinoma cells (HeLa) | 24918059 |
| RLID:01001216 | Nucleus | Nasopharyngeal carcinoma cells | 20498841 |
| RLID:01001217 | Nucleus | Colon adenocarcinoma cells | 20864815 |
| RLID:01001218 | Nucleus | HeLa cells | 22058130 |
| RLID:11000594 | Exosome | Saliva | 19627513 |
| RLID:11000595 | Exosome | Hetastatic gastric cancer cell line (AZ-P7a) | 20949044 |
| RLID:11000596 | Exosome | Breast cancer cell line (MCF-7) | 20976003 |
| RLID:11000597 | Exosome | Primary dendritic cells | 21505438 |
| RLID:11000598 | Exosome | Renal cancer cells | 21670082 |
| RLID:11000599 | Exosome | Breast milk | 22211110 |
| RLID:11000601 | Exosome | Saliva | 23302638 |
| RLID:11000602 | Exosome | Brain tissue | 23382797 |
| RLID:11000603 | Exosome | Plasma | 23663360 |
| RLID:11000604 | Exosome | Human mast cell line (HMC-1) | 24009880 |
| RLID:11000605 | Exosome | Human esophageal cancer cell line (EC9706) | 25184951 |
| RLID:11000606 | Extracellular vesicle | HEK-293T cells | 22849433 |
| RLID:11000607 | Microvesicle | Plasma | 23077538 |
| RLID:11000608 | Microvesicle | Seminal plasma | 23539611 |
| RLID:11000609 | Microvesicle | Follicular fluid | 23666971 |
| RLID:11000610 | Microvesicle | Hepatoma cells | 23771658 |
| RLID-D:11000003 | Exosome | Blood|Breast milk|Chronic lymphocytic leukemia cells|Endothelial cells|Lymphoma tissue|Saliva|Seminal fluid | |
| RLID-D:11000263 | Microvesicle | Blood|Colon cancer cell line (LIM1863)|Fibroblasts|Mesenchymal stem cells|Urine |
ncRNA Disease Information
| Resource | RNA Symbol | Disease | Link |
| MNDR | hsa-let-7c-5p | Diffuse large b cell lymphoma | MNDR-E-MI-00967 |
| MNDR | hsa-let-7c-5p | Splenic marginal zone lymphoma | MNDR-E-MI-00968 |
| MNDR | hsa-let-7c-5p | Oral squamous cell carcinoma | MNDR-E-MI-00969 |
| MNDR | hsa-let-7c-5p | Large cell neuroendocrine cancer | MNDR-E-MI-00970 |
| MNDR | hsa-let-7c-5p | B cell lymphoma of malt type | MNDR-E-MI-00971 |
| MNDR | hsa-let-7c-5p | High-grade serous ovarian carcinoma | MNDR-E-MI-00972 |
| MNDR | hsa-let-7c-5p | Ovarian clear cell carcinoma | MNDR-E-MI-00973 |
| MNDR | hsa-let-7c-5p | Uterine corpus endometrial carcinoma | MNDR-E-MI-00974 |
| MNDR | hsa-let-7c-5p | Lymphoma non-hodgkin | MNDR-E-MI-00975 |
| MNDR | hsa-let-7c-5p | Estrogen-receptor positive breast cancer | MNDR-E-MI-00976 |
| MNDR | hsa-let-7c-5p | Estrogen-receptor negative breast cancer | MNDR-E-MI-00977 |
| MNDR | hsa-let-7c-5p | Progesterone-receptor positive breast cancer | MNDR-E-MI-00978 |
| MNDR | hsa-let-7c-5p | Progesterone-receptor negative breast cancer | MNDR-E-MI-00979 |
| MNDR | hsa-let-7c-5p | Her2-receptor positive breast cancer | MNDR-E-MI-00980 |
| MNDR | hsa-let-7c-5p | Prostate cancer | MNDR-E-MI-00981 |
| MNDR | hsa-let-7c-5p | Gastric cancer | MNDR-E-MI-00982 |
| MNDR | hsa-let-7c-5p | Gastric lymphoma | MNDR-E-MI-00983 |
| MNDR | hsa-let-7c-5p | Alzheimer disease | MNDR-E-MI-00984 |
| MNDR | hsa-let-7c-5p | Bladder cancer | MNDR-E-MI-00985 |
| MNDR | hsa-let-7c-5p | Dysautonomia familial | MNDR-E-MI-00986 |
| MNDR | hsa-let-7c-5p | Head and neck cancer | MNDR-E-MI-00987 |
| MNDR | hsa-let-7c-5p | Leukemia | MNDR-E-MI-00988 |
| MNDR | hsa-let-7c-5p | Cardiovascular disease | MNDR-E-MI-00989 |
| MNDR | hsa-let-7c-5p | Carotid stenosis | MNDR-E-MI-00990 |
| MNDR | hsa-let-7c-5p | Lung cancer | MNDR-E-MI-00991 |
| MNDR | hsa-let-7c-5p | Metabolic syndrome x | MNDR-E-MI-00992 |
| MNDR | hsa-let-7c-5p | Parkinson disease | MNDR-E-MI-00993 |
| MNDR | hsa-let-7c-5p | Breast cancer | MNDR-E-MI-00994 |
| MNDR | hsa-let-7c-5p | Neuroendocrine neoplasia | MNDR-E-MI-00995 |
| MNDR | hsa-let-7c-5p | Pancreatic cancer | MNDR-E-MI-00996 |
| MNDR | hsa-let-7c-5p | Melanoma | MNDR-E-MI-00997 |
| MNDR | hsa-let-7c-5p | Rectum adenocarcinoma | MNDR-E-MI-00998 |
| MNDR | hsa-let-7c-5p | Nephroblastoma | MNDR-E-MI-00999 |
| MNDR | hsa-let-7c-5p | Colon cancer | MNDR-E-MI-01000 |
| MNDR | hsa-let-7c-5p | Colon adenocarcinoma | MNDR-E-MI-01001 |
| MNDR | hsa-let-7c-5p | Multiple sclerosis relapsing-remitting | MNDR-E-MI-01002 |
| MNDR | hsa-let-7c-5p | Familial ovarian cancer | MNDR-E-MI-01003 |
| MNDR | hsa-let-7c-5p | Prostate adenocarcinoma | MNDR-E-MI-01004 |
| MNDR | hsa-let-7c-5p | Carcinoma ductal breast | MNDR-E-MI-01005 |
| MNDR | hsa-let-7c-5p | Glioma | MNDR-E-MI-01006 |
| MNDR | hsa-let-7c-5p | Chordoma | MNDR-E-MI-01007 |
| MNDR | hsa-let-7c-5p | Amyotrophic lateral sclerosis | MNDR-E-MI-01008 |
| MNDR | hsa-let-7c-5p | Osteosarcoma | MNDR-E-MI-01009 |
| MNDR | hsa-let-7c-5p | Middle cerebral artery infarction | MNDR-E-MI-01010 |
| MNDR | hsa-let-7c-5p | Hepatocellular cancer | MNDR-E-MI-01011 |
| MNDR | hsa-let-7c-5p | Uterine cancer | MNDR-E-MI-01012 |
| MNDR | hsa-let-7c-5p | Cervical adenocarcinoma | MNDR-E-MI-01013 |
| MNDR | hsa-let-7c-5p | Gastric adenocarcinoma | MNDR-E-MI-01014 |
| MNDR | hsa-let-7c-5p | Cervical squamous cell carcinoma | MNDR-E-MI-01015 |
| MNDR | hsa-let-7c-5p | Lung squamous cell carcinoma | MNDR-E-MI-01016 |
| MNDR | hsa-let-7c-5p | Lung adenocarcinoma | MNDR-E-MI-01017 |
| MNDR | hsa-let-7c-5p | Thyroid carcinoma | MNDR-E-MI-01018 |
| MNDR | hsa-let-7c-5p | Tuberculosis | MNDR-E-MI-01019 |
| MNDR | hsa-let-7c-5p | Ovarian carcinoma | MNDR-E-MI-01020 |
| MNDR | hsa-let-7c-5p | Bladder urothelial carcinoma | MNDR-E-MI-01021 |
| MNDR | hsa-let-7c-5p | Pancreatic adenocarcinoma | MNDR-E-MI-01022 |
| MNDR | hsa-let-7c-5p | Myasthenia gravis | MNDR-E-MI-01023 |
| MNDR | hsa-let-7c-5p | Carcinoma renal cell | MNDR-E-MI-01024 |
| MNDR | hsa-let-7c-5p | Kidney renal papillary cell carcinoma | MNDR-E-MI-01025 |
| MNDR | hsa-let-7c-5p | Clear cell renal cell carcinoma | MNDR-E-MI-01026 |
| MNDR | hsa-let-7c-5p | Large cell carcinoma | MNDR-E-MI-01027 |
| MNDR | hsa-let-7c-5p | Biliary tract cancer | MNDR-E-MI-01028 |
| MNDR | hsa-let-7c-5p | Intrahepatic cholangiocarcinoma | MNDR-E-MI-01029 |
| MNDR | hsa-let-7c-5p | Cholangiocarcinoma | MNDR-E-MI-01030 |
| MNDR | hsa-let-7c-5p | Esophageal cancer | MNDR-E-MI-01031 |
| MNDR | hsa-let-7c-5p | Head and neck squamous cell carcinoma | MNDR-E-MI-01032 |
| MNDR | hsa-let-7c-5p | Adenoma | MNDR-E-MI-01033 |
| MNDR | hsa-let-7c-5p | Breast invasive carcinoma | MNDR-E-MI-01034 |
| MNDR | hsa-let-7c-5p | Early hepatocellular carcinoma | MNDR-E-MI-01035 |
| MNDR | hsa-let-7c-5p | Familiar ovarian carcinoma | MNDR-E-MI-01036 |
| MNDR | hsa-let-7c-5p | B-cell lymphoma | MNDR-E-MI-01037 |
| MNDR | hsa-let-7c-5p | Rheumatoid arthritis | MNDR-E-MI-01038 |
| MNDR | hsa-let-7c-5p | T-cell leukemia | MNDR-E-MI-01039 |
| MNDR | hsa-let-7c-5p | Retinoblastoma | MNDR-E-MI-01040 |
| MNDR | hsa-let-7c-5p | Neuroblastoma | MNDR-E-MI-01041 |
| MNDR | hsa-let-7c-5p | Barrett's adenocarcinoma | MNDR-E-MI-01042 |
| MNDR | hsa-let-7c-5p | Hodgkin lymphoma | MNDR-E-MI-01043 |
| MNDR | hsa-let-7c-5p | Burkitt lymphoma | MNDR-E-MI-01044 |
| MNDR | hsa-let-7c-5p | Tonsil cancer | MNDR-E-MI-01045 |
| MNDR | hsa-let-7c-5p | Neuromyelitis optica | MNDR-E-MI-01046 |
| MNDR | hsa-let-7c-5p | Acute myeloid leukemia | MNDR-E-MI-01047 |
| MNDR | hsa-let-7c-5p | Colorectal cancer | MNDR-E-MI-01048 |
| MNDR | hsa-let-7c-5p | Nasopharynx carcinoma | MNDR-E-MI-01049 |
| MNDR | hsa-let-7c-5p | Multiple myeloma | MNDR-E-MI-01050 |
| MNDR | hsa-let-7c-5p | Prostatic neoplasms | MNDR-E-MI-01051 |
| MNDR | hsa-let-7c-5p | Reperfusion injury | MNDR-E-MI-01052 |
| MNDR | hsa-let-7c-5p | Epstein-barr virus infections | MNDR-E-MI-01053 |
| MNDR | hsa-let-7c-5p | Barrett's carcinogenesis | MNDR-E-MI-01054 |
| MNDR | hsa-let-7c-5p | Breast cancer her3+ negative | MNDR-E-MI-01055 |
| MNDR | hsa-let-7c-5p | High grade dysplastic nodule | MNDR-E-MI-01056 |
| MNDR | hsa-let-7c-5p | Tubulovillous adenoma | MNDR-E-MI-01057 |
RNA Interaction Information
| Resource | RNA Symbol | Species | Link | RNALocate ID |
| RNAInter | ABCC5 | Homo sapiens | RR00023746 |
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