Basic Information
RNALocate ID: | RLID:02000445 |
RNA Symbol: | NEAT1 |
Localization: | Paraspeckles |
RNA Information
RNA Name: | NEAT1 |
RNA ID: | NCBI:283131|Ensembl:ENSG00000245532 |
RNA Category: | lncRNA |
Species: | Homo sapiens |
Alias: | LINC00084|NCRNA00084|TncRNA|VINC |
Localization Information
PubMed ID: | 19217333 |
Tissue/Cell Line: | Epithelial adenocarcinoma cell line (HeLa) |
Method: | ISH|qRT-PCR |
Linescan analysis demonstrates that NEAT1 RNA (green) is primarily in paraspeckle foci, with little nucleoplasmic signal, while paraspeckle proteins (red) are found throughout the nucleoplasm and concentrate in paraspeckles. Originally published in Mol Cell. Clemson CM, et al, 2009. Reproduced under the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/) |
|
Description: | Importantly, while other paraspeckle components are found diffusely throughout the nucleoplasm, NEAT1 RNA is found almost exclusively as bright tightly-bordered foci that overlap paraspeckles (linescans Figure 1D, H). |
Other Subcellular Localization
RNALocate ID | Localization | Tissue/Cell line | PubMed ID |
RLID:02000434 | Chromatin | HeLa cells | 28536419 |
RLID:02000435 | Cytosol | Human myelogenous leukemia cell line (K-562) | 21613539 |
RLID:02000436 | Nucleus | Cell line (HeLa) | 28484218 |
RLID:02000437 | Nucleus | HeLa cells | 28846091 |
RLID:02000438 | Nucleus | Human colon carcinoma-derived cell line (HCT-116) | 29345294 |
RLID:02000439 | Nucleus | HeLa cells | 31044562 |
RLID:02000440 | Nucleus | Fibroblasts|Lymphoblasts | 17270048 |
RLID:02000441 | Nucleus | HeLa cells | 19217333 |
RLID:02000442 | Nucleus | Placenta | 24280234 |
RLID:02000443 | Nucleus | Colon cancer cells | 24393600 |
RLID:02000444 | Nucleus | BJ foreskin fibroblasts | 25155612 |
RLID:02000446 | Paraspeckles | Cell line (HeLa) | 21240286 |
RLID:02000447 | Paraspeckles | HeLa cells | 26979837 |
RLID:02000448 | Paraspeckles | VCaP cells | 25415230 |
RLID:02000449 | Paraspeckles in the nucleus | Cell line (HCT-116|MCF-7) | 27378782 |
RLID:02001075 | Nucleus | Lung tissue | 30528088 |
RLID-D:02000286 | Chromatin | HeLa-S3 cells|K562 cells | |
RLID-D:02000596 | Cytosol | HCC cell line (HepG2)|HeLa-S3 cells|K562 cells | |
RLID-D:02000814 | Membrane | K562 cells | |
RLID-D:02001058 | Nucleolus | K562 cells | |
RLID-D:02001449 | Nucleoplasm | K562 cells | |
RLID-D:02001973 | Nucleus | HCC cell line (HepG2)|HeLa-S3 cells|K562 cells | |
RLID-D:12003971 | Exosome | Plasma |
ncRNA Disease Information
Resource | RNA Symbol | Disease | Link |
MNDR | NEAT1 | Diffuse large b-cell lymphoma | MNDR-E-LNC-18807 |
MNDR | NEAT1 | Oral squamous cell carcinoma | MNDR-E-LNC-18808 |
MNDR | NEAT1 | Image syndrome | MNDR-E-LNC-18809 |
MNDR | NEAT1 | Triple negative breast cancer | MNDR-E-LNC-18810 |
MNDR | NEAT1 | Acute promyelocytic leukemia | MNDR-E-LNC-18811 |
MNDR | NEAT1 | Nonalcoholic fatty liver disease | MNDR-E-LNC-18812 |
MNDR | NEAT1 | Anaplastic thyroid cancer | MNDR-E-LNC-18813 |
MNDR | NEAT1 | Prostate cancer | MNDR-E-LNC-18814 |
MNDR | NEAT1 | Chronic lymphocytic leukemia | MNDR-E-LNC-18815 |
MNDR | NEAT1 | Gastric cancer | MNDR-E-LNC-18816 |
MNDR | NEAT1 | Alzheimer disease | MNDR-E-LNC-18817 |
MNDR | NEAT1 | Bladder cancer | MNDR-E-LNC-18818 |
MNDR | NEAT1 | Hemorrhagic fever with renal syndrome | MNDR-E-LNC-18819 |
MNDR | NEAT1 | Seizures | MNDR-E-LNC-18820 |
MNDR | NEAT1 | Dengue disease | MNDR-E-LNC-18821 |
MNDR | NEAT1 | Leukemia | MNDR-E-LNC-18822 |
MNDR | NEAT1 | Acute leukemia | MNDR-E-LNC-18823 |
MNDR | NEAT1 | Autism | MNDR-E-LNC-18824 |
MNDR | NEAT1 | Huntington disease | MNDR-E-LNC-18825 |
MNDR | NEAT1 | Cardiovascular disease | MNDR-E-LNC-18826 |
MNDR | NEAT1 | Lung cancer | MNDR-E-LNC-18827 |
MNDR | NEAT1 | Endometrial cancer | MNDR-E-LNC-18828 |
MNDR | NEAT1 | Parkinson disease | MNDR-E-LNC-18829 |
MNDR | NEAT1 | Breast cancer | MNDR-E-LNC-18830 |
MNDR | NEAT1 | Cancer | MNDR-E-LNC-18831 |
MNDR | NEAT1 | Squamous cell carcinoma | MNDR-E-LNC-18832 |
MNDR | NEAT1 | Thyroid cancer | MNDR-E-LNC-18833 |
MNDR | NEAT1 | Pancreatic cancer | MNDR-E-LNC-18834 |
MNDR | NEAT1 | Malignant melanoma | MNDR-E-LNC-18835 |
MNDR | NEAT1 | Atherosclerosis | MNDR-E-LNC-18836 |
MNDR | NEAT1 | Vulva squamous cell carcinoma | MNDR-E-LNC-18837 |
MNDR | NEAT1 | Colon cancer | MNDR-E-LNC-18838 |
MNDR | NEAT1 | Relapsing-remitting multiple sclerosis | MNDR-E-LNC-18839 |
MNDR | NEAT1 | Ovarian cancer | MNDR-E-LNC-18840 |
MNDR | NEAT1 | Hemangioma | MNDR-E-LNC-18841 |
MNDR | NEAT1 | Laryngeal cancer | MNDR-E-LNC-18842 |
MNDR | NEAT1 | Endometrial adenocarcinoma | MNDR-E-LNC-18843 |
MNDR | NEAT1 | Endometrial carcinoma | MNDR-E-LNC-18844 |
MNDR | NEAT1 | Laryngeal squamous cell cancer | MNDR-E-LNC-18845 |
MNDR | NEAT1 | Acute kidney injury | MNDR-E-LNC-18846 |
MNDR | NEAT1 | Glioblastoma | MNDR-E-LNC-18847 |
MNDR | NEAT1 | Astrocytoma | MNDR-E-LNC-18848 |
MNDR | NEAT1 | Glioma | MNDR-E-LNC-18849 |
MNDR | NEAT1 | Amyotrophic lateral sclerosis | MNDR-E-LNC-18850 |
MNDR | NEAT1 | Osteosarcoma | MNDR-E-LNC-18851 |
MNDR | NEAT1 | Hepatocellular cancer | MNDR-E-LNC-18852 |
MNDR | NEAT1 | Gastric adenocarcinoma | MNDR-E-LNC-18853 |
MNDR | NEAT1 | Esophagus squamous cell carcinoma | MNDR-E-LNC-18854 |
MNDR | NEAT1 | Lung squamous cell carcinoma | MNDR-E-LNC-18855 |
MNDR | NEAT1 | Carcinoma lung non-small-cell | MNDR-E-LNC-18856 |
MNDR | NEAT1 | Lung adenocarcinoma | MNDR-E-LNC-18857 |
MNDR | NEAT1 | Thyroid carcinoma | MNDR-E-LNC-18858 |
MNDR | NEAT1 | Papillary thyroid cancer | MNDR-E-LNC-18859 |
MNDR | NEAT1 | Cervical cancer | MNDR-E-LNC-18860 |
MNDR | NEAT1 | Renal cell carcinoma | MNDR-E-LNC-18861 |
MNDR | NEAT1 | Clear cell renal cell carcinoma | MNDR-E-LNC-18862 |
MNDR | NEAT1 | Cholangiocarcinoma | MNDR-E-LNC-18863 |
MNDR | NEAT1 | Esophageal cancer | MNDR-E-LNC-18864 |
MNDR | NEAT1 | HIV | MNDR-E-LNC-18865 |
MNDR | NEAT1 | Kidney diseases | MNDR-E-LNC-18866 |
MNDR | NEAT1 | Acquired immunodeficiency syndrome | MNDR-E-LNC-18867 |
MNDR | NEAT1 | Hepatocellular carcinoma | MNDR-E-LNC-18868 |
MNDR | NEAT1 | Malignant pleural mesothelioma | MNDR-E-LNC-18869 |
MNDR | NEAT1 | Retinoblastoma | MNDR-E-LNC-18870 |
MNDR | NEAT1 | Neuroblastoma | MNDR-E-LNC-18871 |
MNDR | NEAT1 | Osteoarthritis | MNDR-E-LNC-18872 |
MNDR | NEAT1 | Chronic myeloid leukemia | MNDR-E-LNC-18873 |
MNDR | NEAT1 | Burkitt lymphoma | MNDR-E-LNC-18874 |
MNDR | NEAT1 | Degenerative disc disease | MNDR-E-LNC-18875 |
MNDR | NEAT1 | Systemic lupus erythematosus | MNDR-E-LNC-18876 |
MNDR | NEAT1 | Acute myeloid leukemia | MNDR-E-LNC-18877 |
MNDR | NEAT1 | Frontotemporal dementia | MNDR-E-LNC-18878 |
MNDR | NEAT1 | Colorectal cancer | MNDR-E-LNC-18879 |
MNDR | NEAT1 | Nasopharyngeal carcinoma | MNDR-E-LNC-18880 |
MNDR | NEAT1 | Multiple myeloma | MNDR-E-LNC-18881 |
MNDR | NEAT1 | Tdp-43 protein human | MNDR-E-LNC-18882 |
MNDR | NEAT1 | Thyroid cancer papillary | MNDR-E-LNC-18883 |
MNDR | NEAT1 | Esophageal squamous cell cancer | MNDR-E-LNC-18884 |
MNDR | NEAT1 | Liver fibrosis | MNDR-E-LNC-18885 |
MNDR | NEAT1 | Nasopharyngeal cancer | MNDR-E-LNC-18886 |
MNDR | NEAT1 | Hantavirus infection | MNDR-E-LNC-18887 |
MNDR | NEAT1 | Lymph node metastasis | MNDR-E-LNC-18888 |
RNA Interaction Information
Resource | RNA Symbol | Species | Link | RNALocate ID |
RNAInter | ADARB2 | Homo sapiens | RR00043493 |
TOP