Basic Information
| RNALocate ID: | RLID:01002839 |
| RNA Symbol: | hsa-miR-1976 |
| Localization: | Cytoplasm |
RNA Information
| RNA Name: | hsa-miR-1976 |
| RNA ID: | miRBase:MIMAT0009451 |
| RNA Category: | miRNA |
| Species: | Homo sapiens |
Localization Information
| PubMed ID: | 21695135 |
| Tissue/Cell Line: | Cell line (HeLa) |
| Method: | Microarray |
|
Heatmap showing the 57 miRNAs differentially expressed in HeLa cells from mitochondrial and cytosolic RNA. Three independent microarray profiling experiments (microarray n1, n2 and n3) are shown and reproducibly revealed 13 miRNAs enriched in mitochondrial RNA. Originally published in PLoS One. Bandiera S, et al, 2011. Reproduced under the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/) |
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| Description: | While 44 miRNAs showed a greater enrichment in the cytosolic Hy3-labeled RNA fraction, 13 miRNAs were significantly and reproducibly enriched in the mitochondrial Hy5-labeled RNA sample (ranging from 1.5- to 56-fold), namely hsa-miR-1973, hsa-miR-1275, hsa-miR-494, hsa-miR-513a-5p, hsa-miR-1246, hsa-miR-328, hsa-miR-1908, hsa-miR-1972, hsa-miR-1974, hsa-miR-1977, hsa-miR-638, hsa-miR-1978 and hsa-miR-1201 (Figure 5A). Data are collected from Figure 5. |
Other Subcellular Localization
| RNALocate ID | Localization | Tissue/Cell line | PubMed ID |
| RLID:01002840 | Mitochondrion | Skeletal muscle cells | 27563705 |
| RLID:11004439 | Exosome | Breast cancer cell lines (MCF-7|MDA-MB-231) | 24468161 |
| RLID-D:11001775 | Exosome | Breast milk|Cell lines|Epididymal epithelial cells|Osteoblast|Plasma|Primary glioblastoma neurosphere cells|Primary keratinocyte|Saliva|Serum|Urine | |
| RLID-D:11004216 | Microvesicle | Cell lines(GBM46|GBM8|HaCaT|K562|MCF-10A|MCF-7|MGG75)|Plasma|Primary glioblastoma neurosphere cells|Primary keratinocytes |
ncRNA Disease Information
| Resource | RNA Symbol | Disease | Link |
| MNDR | hsa-miR-1976 | Uterine corpus endometrial carcinoma | MNDR-E-MI-24415 |
| MNDR | hsa-miR-1976 | Gastric cancer | MNDR-E-MI-24416 |
| MNDR | hsa-miR-1976 | Alzheimer disease | MNDR-E-MI-24417 |
| MNDR | hsa-miR-1976 | Parkinson disease | MNDR-E-MI-24418 |
| MNDR | hsa-miR-1976 | Pancreatic cancer | MNDR-E-MI-24419 |
| MNDR | hsa-miR-1976 | Rectum adenocarcinoma | MNDR-E-MI-24420 |
| MNDR | hsa-miR-1976 | Nephroblastoma | MNDR-E-MI-24421 |
| MNDR | hsa-miR-1976 | Colon cancer | MNDR-E-MI-24422 |
| MNDR | hsa-miR-1976 | Colon adenocarcinoma | MNDR-E-MI-24423 |
| MNDR | hsa-miR-1976 | Prostate adenocarcinoma | MNDR-E-MI-24424 |
| MNDR | hsa-miR-1976 | Liver cancer | MNDR-E-MI-24425 |
| MNDR | hsa-miR-1976 | Gastric adenocarcinoma | MNDR-E-MI-24426 |
| MNDR | hsa-miR-1976 | Cervical squamous cell carcinoma | MNDR-E-MI-24427 |
| MNDR | hsa-miR-1976 | Lung squamous cell carcinoma | MNDR-E-MI-24428 |
| MNDR | hsa-miR-1976 | Carcinoma lung non-small-cell | MNDR-E-MI-24429 |
| MNDR | hsa-miR-1976 | Lung adenocarcinoma | MNDR-E-MI-24430 |
| MNDR | hsa-miR-1976 | Thyroid carcinoma | MNDR-E-MI-24431 |
| MNDR | hsa-miR-1976 | Bladder urothelial carcinoma | MNDR-E-MI-24432 |
| MNDR | hsa-miR-1976 | Pancreatic adenocarcinoma | MNDR-E-MI-24433 |
| MNDR | hsa-miR-1976 | Carcinoma renal cell | MNDR-E-MI-24434 |
| MNDR | hsa-miR-1976 | Kidney renal papillary cell carcinoma | MNDR-E-MI-24435 |
| MNDR | hsa-miR-1976 | Cholangiocarcinoma | MNDR-E-MI-24436 |
| MNDR | hsa-miR-1976 | Esophageal cancer | MNDR-E-MI-24437 |
| MNDR | hsa-miR-1976 | Head and neck squamous cell carcinoma | MNDR-E-MI-24438 |
| MNDR | hsa-miR-1976 | Skin cutaneous melanoma | MNDR-E-MI-24439 |
| MNDR | hsa-miR-1976 | Skin melanoma | MNDR-E-MI-24440 |
| MNDR | hsa-miR-1976 | Colorectal cancer | MNDR-E-MI-24441 |
| MNDR | hsa-miR-1976 | Nasopharynx carcinoma | MNDR-E-MI-24442 |
| MNDR | hsa-miR-1976 | Nasopharyngeal cancer | MNDR-E-MI-24443 |
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