Basic Information
RNALocate ID: RLID:00023277
RNA Symbol: CDC6
Localization: Nucleus
Localization from RNA-seq Dataset:  
RNA Information
RNA Name: CDC6
RNA ID: NCBI:990|Ensembl:ENSG00000094804
RNA Category: mRNA
Species: Homo sapiens
Alias: CDC18L|HsCDC18|HsCDC6|MGORS5
Sequence:
Localization Information
PubMed ID: 24393600
Tissue/Cell Line: Colon cancer cells
Method: Next-generation RNA sequencing
Description: The RNA composition of the subcellular fractions differs significantly from each other, but lncRNAs are found in all locations. A subset of specific lncRNAs is enriched in the nucleus but surprisingly the majority is enriched in the cytosol and in ribosomal fractions. The ribosomal enriched lncRNAs include H19 and TUG1. Most studies on lncRNAs have focused on the regulatory function of these transcripts in the nucleus. We demonstrate that only a minority of all lncRNAs are nuclear enriched. Our findings suggest that many lncRNAs may have a function in cytoplasmic processes, and in particular in ribosome complexes. Data were collected from additional file 5.Overall, we consider clusters I, II and III as enriched in the nucleus; IV and V as enriched in the ribosome-free cytosol; and VI, VII, VIII, IX and X as enriched in the ribosomes.
Other Subcellular Localization
RNALocate ID Localization Tissue/Cell line PubMed ID
RLID:00023274 Cytoplasm Nasopharyngeal carcinoma cells 20498841
RLID:00023275 Cytosol Human myelogenous leukemia cell line (K-562) 21613539
RLID:00023276 Nucleus Nasopharyngeal carcinoma cells 20498841
RLID:00023278 Ribosome HEK-293 cells 22199352
RLID-D:00007507 Chromatin K562 cells
RLID-D:00013803 Cytosol HCC cell line (HepG2)|K562 cells
RLID-D:00024317 Nucleolus K562 cells
RLID-D:00031787 Nucleoplasm K562 cells
RLID-D:10017763 Exosome Blood
RNA Interaction Information
Resource RNA Symbol Species Link RNALocate ID
RNAInter hsa-miR-26a-5p Homo sapiens RR00306508
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