Basic Information
RNALocate ID: RLID:00017495
RNA Symbol: STAT5A
Localization: Ribosome
RNA Information
RNA Name: STAT5A
RNA ID: NCBI:6776|Ensembl:ENSG00000126561
RNA Category: mRNA
Species: Homo sapiens
Alias: MGF|STAT5
Sequence:
Localization Information
PubMed ID: 24393600
Tissue/Cell Line: Colon cancer cells
Method: Next-generation RNA sequencing
Description: The RNA composition of the subcellular fractions differs significantly from each other, but lncRNAs are found in all locations. A subset of specific lncRNAs is enriched in the nucleus but surprisingly the majority is enriched in the cytosol and in ribosomal fractions. The ribosomal enriched lncRNAs include H19 and TUG1. Most studies on lncRNAs have focused on the regulatory function of these transcripts in the nucleus. We demonstrate that only a minority of all lncRNAs are nuclear enriched. Our findings suggest that many lncRNAs may have a function in cytoplasmic processes, and in particular in ribosome complexes. Data were collected from additional file 5.Overall, we consider clusters I, II and III as enriched in the nucleus; IV and V as enriched in the ribosome-free cytosol; and VI, VII, VIII, IX and X as enriched in the ribosomes.
Other Subcellular Localization
RNALocate ID Localization Tissue/Cell line PubMed ID
RLID-D:00005489 Chromatin K562 cells
RLID-D:00012219 Cytosol K562 cells
RLID-D:00022731 Nucleolus K562 cells
RLID-D:00029843 Nucleoplasm K562 cells
RLID-D:00038384 Nucleus K562 cells
RLID-D:10013488 Exosome Blood
RNA Interaction Information
Resource RNA Symbol Species Link RNALocate ID
RNAInter hsa-miR-141-3p Homo sapiens RR01368890
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