Basic Information
RNALocate ID: RLID:00007210
RNA Symbol: AGO3
Localization: Nucleus
Localization from RNA-seq Dataset:  
RNA Information
RNA Name: AGO3
RNA ID: NCBI:192669|Ensembl:ENSG00000126070
RNA Category: mRNA
Species: Homo sapiens
Alias: EIF2C3
Sequence:
Localization Information
PubMed ID: 24393600
Tissue/Cell Line: Colon cancer cells
Method: Next-generation RNA sequencing
Description: The RNA composition of the subcellular fractions differs significantly from each other, but lncRNAs are found in all locations. A subset of specific lncRNAs is enriched in the nucleus but surprisingly the majority is enriched in the cytosol and in ribosomal fractions. The ribosomal enriched lncRNAs include H19 and TUG1. Most studies on lncRNAs have focused on the regulatory function of these transcripts in the nucleus. We demonstrate that only a minority of all lncRNAs are nuclear enriched. Our findings suggest that many lncRNAs may have a function in cytoplasmic processes, and in particular in ribosome complexes. Data were collected from additional file 5.Overall, we consider clusters I, II and III as enriched in the nucleus; IV and V as enriched in the ribosome-free cytosol; and VI, VII, VIII, IX and X as enriched in the ribosomes.
Homology Information
RNA Symbol Gene ID Species Detail
AGO1 NCBI:841262 Arabidopsis thaliana Go to
Ago3 NCBI:214150 Mus musculus Go to
Other Subcellular Localization
RNALocate ID Localization Tissue/Cell line PubMed ID
RLID-D:00001282 Chromatin K562 cells
RLID-D:00008655 Cytosol HCC cell line (HepG2)|K562 cells
RLID-D:00014083 Insoluble cytoplasm HCC cell line (HepG2)
RLID-D:00015804 Membrane HCC cell line (HepG2)
RLID-D:00019475 Nucleolus K562 cells
RLID-D:00025647 Nucleoplasm K562 cells
RLID-D:00033435 Nucleus HCC cell line (HepG2)|HeLa-S3 cells|K562 cells
RLID-D:10003659 Exosome Blood
RNA Interaction Information
Resource RNA Symbol Species Link RNALocate ID
RNAInter SNHG16 Homo sapiens RR00055761
TOP