Basic Information
RNALocate ID: RLID:00006875
RNA Symbol: CNST
Localization: Ribosome
Localization from RNA-seq Dataset:  
RNA Information
RNA Name: CNST
RNA ID: NCBI:163882|Ensembl:ENSG00000162852
RNA Category: mRNA
Species: Homo sapiens
Alias: C1orf71|PPP1R64
Sequence:
Localization Information
PubMed ID: 24393600
Tissue/Cell Line: Colon cancer cells
Method: Next-generation RNA sequencing
Description: The RNA composition of the subcellular fractions differs significantly from each other, but lncRNAs are found in all locations. A subset of specific lncRNAs is enriched in the nucleus but surprisingly the majority is enriched in the cytosol and in ribosomal fractions. The ribosomal enriched lncRNAs include H19 and TUG1. Most studies on lncRNAs have focused on the regulatory function of these transcripts in the nucleus. We demonstrate that only a minority of all lncRNAs are nuclear enriched. Our findings suggest that many lncRNAs may have a function in cytoplasmic processes, and in particular in ribosome complexes. Data were collected from additional file 5.Overall, we consider clusters I, II and III as enriched in the nucleus; IV and V as enriched in the ribosome-free cytosol; and VI, VII, VIII, IX and X as enriched in the ribosomes.
Homology Information
RNA Symbol Gene ID Species Detail
Cnst NCBI:226744 Mus musculus Go to
Other Subcellular Localization
RNALocate ID Localization Tissue/Cell line PubMed ID
RLID-D:00001166 Chromatin K562 cells
RLID-D:00008539 Cytosol K562 cells
RLID-D:00019374 Nucleolus K562 cells
RLID-D:00025530 Nucleoplasm K562 cells
RLID-D:00033291 Nucleus HCC cell line (HepG2)|K562 cells
RLID-D:10003330 Exosome Blood
RNA Interaction Information
Resource RNA Symbol Species Link RNALocate ID
RNAInter SNHG16 Homo sapiens RR00348214
TOP