Basic Information
RNALocate ID: | RLID:20000517 |
RNA Symbol: | ACTB |
Localization: | Cell leading edge |
RNA Information
RNA Name: | β-actin |
RNA ID: | NCBI:396526|Ensembl:ENSGALG00000009621 |
RNA Category: | mRNA |
Species: | Gallus gallus |
Alias: | Bact|actin |
Localization Information
PubMed ID: | 15923655 |
Tissue/Cell Line: | Fibroblasts |
Method: | FISH |
Description: | Having observed that Arp2/3 complex and β-actin mRNAs are localized to the protrusions of fibroblasts, we further asked whether the mRNAs of the Arp2/3 complex physically associate with each other or with β-actin mRNA. If the subunit mRNAs of the Arp2/3 complex were co-transported, they should be found to be associated with each other.To address these questions, double detection of two types of mRNAs simultaneously in the same cells was performed by sequential FISH-TSA. As shown in Fig. 5A-C, Arp3 mRNA appears not to be precisely colocalized with β-actin mRNA, although they both concentrate together in the protrusions. In addition, the Arp2 and Arp3 mRNAs also do not colocalize, although they are both concentrated together in the protrusions (Fig. 5D-F). |
Homology Information
RNA Symbol | Gene ID | Species | Detail |
ACTB | NCBI:60 | Homo sapiens | Go to |
Actb | NCBI:11461 | Mus musculus | Go to |
Actb | NCBI:81822 | Rattus norvegicus | Go to |
Other Subcellular Localization
TOP