Basic Information
| RNALocate ID: | RLID:11001530 |
| RNA Symbol: | hsa-miR-221-3p |
| Localization: | Exosome |
RNA Information
| RNA Name: | hsa-miR-221 |
| RNA ID: | miRBase:MIMAT0000278 |
| RNA Category: | miRNA |
| Species: | Homo sapiens |
Localization Information
| PubMed ID: | 22895844 |
| Tissue/Cell Line: | Colorectal cancer cell lines (HCT-15|SW480|WiDr) |
| Method: | RT-PCR |
| Description: | When the RNA species within exosomes derived from the three CRC cell lines were examined, the mRNAs of housekeeping genes such as ACTB and GAPDH, the microRNAs such as miR-21, miR-192 and miR-221, and the natural antisense RNAs of LRRC24, MDM2 and CDKN1A genes, were detected. |
Other Subcellular Localization
| RNALocate ID | Localization | Tissue/Cell line | PubMed ID |
| RLID:01001665 | Cytoplasm | Neural progenitor cells | 21363885 |
| RLID:01001666 | Cytoplasm | Cell line (HeLa) | 21695135 |
| RLID:01001667 | Cytoplasm | Breast adenocarcinoma cells (MCF-7)|Cervical adenocarcinoma cells (HeLa) | 24918059 |
| RLID:01001668 | Mitochondrion | HEK-293 cells|HeLa cells|Myotube | 27396686 |
| RLID:01001669 | Mitochondrion | Skeletal muscle myoblasts | 21637849 |
| RLID:01001670 | Mitochondrion | Cell line (HEK-293|HeLa) | 22984580 |
| RLID:01001671 | Nucleus | Breast adenocarcinoma cells (MCF-7)|Cervical adenocarcinoma cells (HeLa) | 24918059 |
| RLID:01001672 | Nucleolus | Cervical adenocarcinoma cells (HeLa) | 24918059 |
| RLID:01001673 | Nucleus | Nasopharyngeal carcinoma cells | 20498841 |
| RLID:11001529 | Exosome | Primary dendritic cells|T cell line (J77) | 21505438 |
| RLID:11001531 | Exosome | Brain tissue | 23382797 |
| RLID:11001532 | Exosome | Plasma | 23663360 |
| RLID:11001533 | Exosome | Human mast cell line (HMC-1) | 24009880 |
| RLID:11001534 | Exosome | Colon cancer cell line (LIM1863) | 25330373 |
| RLID:11001535 | Extracellular vesicle | HEK-293T cells | 22849433 |
| RLID:11001536 | Microvesicle | Plasma | 23077538 |
| RLID:11001537 | Microvesicle | Seminal plasma | 23539611 |
| RLID-D:11000063 | Exosome | Blood|B lymphoblastoid cells|Breast tissue|Chronic lymphocytic leukemia cells|Colon tissue|Endothelial cells|Epithelial cells|Kidney tissue|Mast cells|Tongue tissue | |
| RLID-D:11000337 | Microvesicle | Blood|Colon cancer cell line (LIM1863)|Fibroblasts|Mesenchymal stem cells|Urine |
ncRNA Disease Information
| Resource | RNA Symbol | Disease | Link |
| MNDR | hsa-miR-221-3p | Splenic marginal zone lymphoma | MNDR-E-MI-30532 |
| MNDR | hsa-miR-221-3p | Multiple sclerosis chronic progressive | MNDR-E-MI-30533 |
| MNDR | hsa-miR-221-3p | Oral squamous cell carcinoma | MNDR-E-MI-30534 |
| MNDR | hsa-miR-221-3p | Follicular cleaved lymphoma | MNDR-E-MI-30535 |
| MNDR | hsa-miR-221-3p | Medulloblastoma | MNDR-E-MI-30536 |
| MNDR | hsa-miR-221-3p | Small intestinal neuroendocrine tumor | MNDR-E-MI-30537 |
| MNDR | hsa-miR-221-3p | High-grade serous ovarian carcinoma | MNDR-E-MI-30538 |
| MNDR | hsa-miR-221-3p | Uterine corpus endometrial carcinoma | MNDR-E-MI-30539 |
| MNDR | hsa-miR-221-3p | Lymphoma | MNDR-E-MI-30540 |
| MNDR | hsa-miR-221-3p | Lymphoma non-hodgkin | MNDR-E-MI-30541 |
| MNDR | hsa-miR-221-3p | Estrogen-receptor negative breast cancer | MNDR-E-MI-30542 |
| MNDR | hsa-miR-221-3p | Progesterone-receptor negative breast cancer | MNDR-E-MI-30543 |
| MNDR | hsa-miR-221-3p | Her2-receptor positive breast cancer | MNDR-E-MI-30544 |
| MNDR | hsa-miR-221-3p | Acute promyelocytic leukemia | MNDR-E-MI-30545 |
| MNDR | hsa-miR-221-3p | Breast cancer luminal b | MNDR-E-MI-30546 |
| MNDR | hsa-miR-221-3p | Niemann-pick disease type c | MNDR-E-MI-30547 |
| MNDR | hsa-miR-221-3p | Precursor cell lymphoblastic leukemia-lymphoma | MNDR-E-MI-30548 |
| MNDR | hsa-miR-221-3p | Colorectal carcinoma | MNDR-E-MI-30549 |
| MNDR | hsa-miR-221-3p | Small intestine cancer | MNDR-E-MI-30550 |
| MNDR | hsa-miR-221-3p | Dermatomyositis | MNDR-E-MI-30551 |
| MNDR | hsa-miR-221-3p | Prostate cancer | MNDR-E-MI-30552 |
| MNDR | hsa-miR-221-3p | Prostate carcinoma | MNDR-E-MI-30553 |
| MNDR | hsa-miR-221-3p | Chronic lymphocytic leukemia | MNDR-E-MI-30554 |
| MNDR | hsa-miR-221-3p | Gastric cancer | MNDR-E-MI-30555 |
| MNDR | hsa-miR-221-3p | Gastric lymphoma | MNDR-E-MI-30556 |
| MNDR | hsa-miR-221-3p | Alzheimer disease | MNDR-E-MI-30557 |
| MNDR | hsa-miR-221-3p | Bladder cancer | MNDR-E-MI-30558 |
| MNDR | hsa-miR-221-3p | Dysautonomia familial | MNDR-E-MI-30559 |
| MNDR | hsa-miR-221-3p | Polycystic ovary syndrome | MNDR-E-MI-30560 |
| MNDR | hsa-miR-221-3p | Myotonic dystrophy | MNDR-E-MI-30561 |
| MNDR | hsa-miR-221-3p | Muscular dystrophy duchenne | MNDR-E-MI-30562 |
| MNDR | hsa-miR-221-3p | Facioscapulohumeral muscular dystrophy | MNDR-E-MI-30563 |
| MNDR | hsa-miR-221-3p | Head and neck cancer | MNDR-E-MI-30564 |
| MNDR | hsa-miR-221-3p | Leukemia | MNDR-E-MI-30565 |
| MNDR | hsa-miR-221-3p | Huntington disease | MNDR-E-MI-30566 |
| MNDR | hsa-miR-221-3p | Chorea | MNDR-E-MI-30567 |
| MNDR | hsa-miR-221-3p | Cardiovascular disease | MNDR-E-MI-30568 |
| MNDR | hsa-miR-221-3p | Carotid stenosis | MNDR-E-MI-30569 |
| MNDR | hsa-miR-221-3p | Brain cancer | MNDR-E-MI-30570 |
| MNDR | hsa-miR-221-3p | Lung cancer | MNDR-E-MI-30571 |
| MNDR | hsa-miR-221-3p | Down syndrome | MNDR-E-MI-30572 |
| MNDR | hsa-miR-221-3p | Parkinson disease | MNDR-E-MI-30573 |
| MNDR | hsa-miR-221-3p | Niemann-pick disease | MNDR-E-MI-30574 |
| MNDR | hsa-miR-221-3p | Major depressive disorder | MNDR-E-MI-30575 |
| MNDR | hsa-miR-221-3p | Basal-like breast cancer | MNDR-E-MI-30576 |
| MNDR | hsa-miR-221-3p | Vascular diseases | MNDR-E-MI-30577 |
| MNDR | hsa-miR-221-3p | Thyroid cancer | MNDR-E-MI-30578 |
| MNDR | hsa-miR-221-3p | Pituitary neoplasms | MNDR-E-MI-30579 |
| MNDR | hsa-miR-221-3p | Pancreatic cancer | MNDR-E-MI-30580 |
| MNDR | hsa-miR-221-3p | Hepatitis C | MNDR-E-MI-30581 |
| MNDR | hsa-miR-221-3p | Melanoma | MNDR-E-MI-30582 |
| MNDR | hsa-miR-221-3p | Atherosclerosis | MNDR-E-MI-30583 |
| MNDR | hsa-miR-221-3p | Nephroblastoma | MNDR-E-MI-30584 |
| MNDR | hsa-miR-221-3p | Colon cancer | MNDR-E-MI-30585 |
| MNDR | hsa-miR-221-3p | Essential thrombocythemia | MNDR-E-MI-30586 |
| MNDR | hsa-miR-221-3p | Ischemic attack transient | MNDR-E-MI-30587 |
| MNDR | hsa-miR-221-3p | Multiple sclerosis relapsing-remitting | MNDR-E-MI-30588 |
| MNDR | hsa-miR-221-3p | Ovarian cancer | MNDR-E-MI-30589 |
| MNDR | hsa-miR-221-3p | Prostate adenocarcinoma | MNDR-E-MI-30590 |
| MNDR | hsa-miR-221-3p | Carcinoma ductal breast | MNDR-E-MI-30591 |
| MNDR | hsa-miR-221-3p | Glioblastoma | MNDR-E-MI-30592 |
| MNDR | hsa-miR-221-3p | Astrocytoma | MNDR-E-MI-30593 |
| MNDR | hsa-miR-221-3p | Glioma | MNDR-E-MI-30594 |
| MNDR | hsa-miR-221-3p | Chordoma | MNDR-E-MI-30595 |
| MNDR | hsa-miR-221-3p | Amyotrophic lateral sclerosis | MNDR-E-MI-30596 |
| MNDR | hsa-miR-221-3p | Epilepsy temporal lobe | MNDR-E-MI-30597 |
| MNDR | hsa-miR-221-3p | Osteosarcoma | MNDR-E-MI-30598 |
| MNDR | hsa-miR-221-3p | Pediatric osteosarcoma | MNDR-E-MI-30599 |
| MNDR | hsa-miR-221-3p | Coronary artery disease | MNDR-E-MI-30600 |
| MNDR | hsa-miR-221-3p | Carotid artery thrombosis | MNDR-E-MI-30601 |
| MNDR | hsa-miR-221-3p | Inclusion body myositis | MNDR-E-MI-30602 |
| MNDR | hsa-miR-221-3p | Pancreatic ductal adenocarcinoma | MNDR-E-MI-30603 |
| MNDR | hsa-miR-221-3p | Liver cancer | MNDR-E-MI-30604 |
| MNDR | hsa-miR-221-3p | Uterine cancer | MNDR-E-MI-30605 |
| MNDR | hsa-miR-221-3p | Cervical adenocarcinoma | MNDR-E-MI-30606 |
| MNDR | hsa-miR-221-3p | Gastric adenocarcinoma | MNDR-E-MI-30607 |
| MNDR | hsa-miR-221-3p | Pituitary adenoma | MNDR-E-MI-30608 |
| MNDR | hsa-miR-221-3p | Lung squamous cell carcinoma | MNDR-E-MI-30609 |
| MNDR | hsa-miR-221-3p | Carcinoma lung non-small-cell | MNDR-E-MI-30610 |
| MNDR | hsa-miR-221-3p | Lung adenocarcinoma | MNDR-E-MI-30611 |
| MNDR | hsa-miR-221-3p | Adrenocortical carcinoma | MNDR-E-MI-30612 |
| MNDR | hsa-miR-221-3p | Thyroid carcinoma | MNDR-E-MI-30613 |
| MNDR | hsa-miR-221-3p | Papillary thyroid carcinoma | MNDR-E-MI-30614 |
| MNDR | hsa-miR-221-3p | Ovarian carcinoma | MNDR-E-MI-30615 |
| MNDR | hsa-miR-221-3p | Bladder urothelial carcinoma | MNDR-E-MI-30616 |
| MNDR | hsa-miR-221-3p | Pancreatic adenocarcinoma | MNDR-E-MI-30617 |
| MNDR | hsa-miR-221-3p | Cervical cancer | MNDR-E-MI-30618 |
| MNDR | hsa-miR-221-3p | Myasthenia gravis autoimmune experimental | MNDR-E-MI-30619 |
| MNDR | hsa-miR-221-3p | Carcinoma renal cell | MNDR-E-MI-30620 |
| MNDR | hsa-miR-221-3p | Chromophobe renal cell carcinoma | MNDR-E-MI-30621 |
| MNDR | hsa-miR-221-3p | Biliary tract cancer | MNDR-E-MI-30622 |
| MNDR | hsa-miR-221-3p | Intrahepatic cholangiocarcinoma | MNDR-E-MI-30623 |
| MNDR | hsa-miR-221-3p | Cholangiocarcinoma | MNDR-E-MI-30624 |
| MNDR | hsa-miR-221-3p | Esophageal cancer | MNDR-E-MI-30625 |
| MNDR | hsa-miR-221-3p | Oncocytoma | MNDR-E-MI-30626 |
| MNDR | hsa-miR-221-3p | Lung small cell carcinoma | MNDR-E-MI-30627 |
| MNDR | hsa-miR-221-3p | Gastric carcinoma | MNDR-E-MI-30628 |
| MNDR | hsa-miR-221-3p | Fibromyalgia | MNDR-E-MI-30629 |
| MNDR | hsa-miR-221-3p | Adenoma | MNDR-E-MI-30630 |
| MNDR | hsa-miR-221-3p | Breast invasive carcinoma | MNDR-E-MI-30631 |
| MNDR | hsa-miR-221-3p | Hepatocellular carcinoma | MNDR-E-MI-30632 |
| MNDR | hsa-miR-221-3p | Embryonal cancer | MNDR-E-MI-30633 |
| MNDR | hsa-miR-221-3p | B-cell lymphoma | MNDR-E-MI-30634 |
| MNDR | hsa-miR-221-3p | Rheumatoid arthritis | MNDR-E-MI-30635 |
| MNDR | hsa-miR-221-3p | T-cell leukemia | MNDR-E-MI-30636 |
| MNDR | hsa-miR-221-3p | Retinoblastoma | MNDR-E-MI-30637 |
| MNDR | hsa-miR-221-3p | Neuroblastoma | MNDR-E-MI-30638 |
| MNDR | hsa-miR-221-3p | Thyroid hurthle cell carcinoma | MNDR-E-MI-30639 |
| MNDR | hsa-miR-221-3p | Hodgkin lymphoma | MNDR-E-MI-30640 |
| MNDR | hsa-miR-221-3p | Burkitt lymphoma | MNDR-E-MI-30641 |
| MNDR | hsa-miR-221-3p | Cutaneous melanoma | MNDR-E-MI-30642 |
| MNDR | hsa-miR-221-3p | Acute myelocytic leukemia | MNDR-E-MI-30643 |
| MNDR | hsa-miR-221-3p | Colorectal cancer | MNDR-E-MI-30644 |
| MNDR | hsa-miR-221-3p | Nasopharynx carcinoma | MNDR-E-MI-30645 |
| MNDR | hsa-miR-221-3p | Type 2 diabetes mellitus | MNDR-E-MI-30646 |
| MNDR | hsa-miR-221-3p | Acute myocardial infarction | MNDR-E-MI-30647 |
| MNDR | hsa-miR-221-3p | Multiple myeloma | MNDR-E-MI-30648 |
| MNDR | hsa-miR-221-3p | Acute lymphoblastic leukemia | MNDR-E-MI-30649 |
| MNDR | hsa-miR-221-3p | Ependymoma | MNDR-E-MI-30650 |
| MNDR | hsa-miR-221-3p | Cardiomegaly | MNDR-E-MI-30651 |
| MNDR | hsa-miR-221-3p | Nasopharyngeal cancer | MNDR-E-MI-30652 |
| MNDR | hsa-miR-221-3p | Prostatic neoplasms | MNDR-E-MI-30653 |
| MNDR | hsa-miR-221-3p | Polymyositis | MNDR-E-MI-30654 |
| MNDR | hsa-miR-221-3p | Epstein-barr virus infections | MNDR-E-MI-30655 |
| MNDR | hsa-miR-221-3p | Mptp poisoning | MNDR-E-MI-30656 |
| MNDR | hsa-miR-221-3p | Intracranial hemorrhage hypertensive | MNDR-E-MI-30657 |
| MNDR | hsa-miR-221-3p | Stroke lacunar | MNDR-E-MI-30658 |
| MNDR | hsa-miR-221-3p | Duke C | MNDR-E-MI-30659 |
| MNDR | hsa-miR-221-3p | Tubulovillous adenoma | MNDR-E-MI-30660 |
RNA Interaction Information
| Resource | RNA Symbol | Species | Link | RNALocate ID |
| RNAInter | ADAM1A | Homo sapiens | RR00040682 |
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