Basic Information
RNALocate ID: RLID:11001278
RNA Symbol: hsa-miR-198
Localization: Exosome
RNA Information
RNA Name: hsa-miR-198
RNA ID: miRBase:MIMAT0000228
RNA Category: miRNA
Species: Homo sapiens
Sequence:
Localization Information
PubMed ID: 24468161
Tissue/Cell Line: Breast cancer cell lines (MCF-7|MDA-MB-231)
Method: Microarray|RT-PCR

Quantitative real-time PCR of miRNAs performed to validate the microarray data. Down-regulation of mir-198 in MCF-Exo and up-regulation of let-7a, mir-328, mir-130a, mir-149, mir-603, and mir-92b from microarray experiments were validated by quantitative PCR analysis (*P < 0.01).

Originally published in BMC Cancer. Kruger S, et al, 2014. Reproduced under the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/)
Description: Differential gene expression in exosome-like vesicles. A) Hierarchical clustering was used to display miRNAs differentially expressed in each vesicle type. The extent of green (decreased fold change) or red (increased fold change) colors is directly proportional to the magnitude of differential expression of miRNAs. B) miRNA profiles of the MDA-Exo versus MCF-Exo. Bars represent fold change of hybridization signals in MDA-Exo against MCF-Exo. Blue and red bars display relatively higher miRNA expressions in MDA-Exo and MCF-Exo, respectively. Data are collected from Figure 3.
Other Subcellular Localization
RNALocate ID Localization Tissue/Cell line PubMed ID
RLID:01001559 Cytoplasm Nasopharyngeal carcinoma cells 20498841
RLID:01001560 Mitochondrion Liver tissue 27396686
RLID:01001561 Mitochondrion Liver cells 19106625
RLID:01001562 Nucleus Nasopharyngeal carcinoma cells 20498841
RLID:11001274 Exosome Primary T lymphocytes 24356509
RLID:11001275 Exosome B cell line (Raji)|Jurkat-derived T cell line (J77cl20) 21505438
RLID:11001276 Exosome Brain tissue 23382797
RLID:11001277 Exosome Human mast cell line (HMC-1) 24009880
RLID:11001279 Microvesicle Seminal plasma 23539611
RLID-D:11001163 Exosome Breast milk|Cell lines|Epididymal epithelial cells|Osteoblast|Plasma|Primary glioblastoma neurosphere cells|Primary keratinocyte|Saliva|Serum|Urine
RLID-D:11003912 Microvesicle Cell lines(GBM46|GBM8|HaCaT|K562|MCF-10A|MCF-7|MGG75)|Plasma|Primary glioblastoma neurosphere cells|Primary keratinocytes
ncRNA Disease Information
Resource RNA Symbol Disease Link
MNDR hsa-miR-198 Splenic marginal zone lymphoma MNDR-E-MI-24465
MNDR hsa-miR-198 Oral squamous cell carcinoma MNDR-E-MI-24466
MNDR hsa-miR-198 Lymphoma MNDR-E-MI-24467
MNDR hsa-miR-198 Lymphoma non-hodgkin MNDR-E-MI-24468
MNDR hsa-miR-198 Estrogen-receptor positive breast cancer MNDR-E-MI-24469
MNDR hsa-miR-198 Estrogen-receptor negative breast cancer MNDR-E-MI-24470
MNDR hsa-miR-198 Progesterone-receptor positive breast cancer MNDR-E-MI-24471
MNDR hsa-miR-198 Progesterone-receptor negative breast cancer MNDR-E-MI-24472
MNDR hsa-miR-198 Her2-receptor positive breast cancer MNDR-E-MI-24473
MNDR hsa-miR-198 Breast cancer luminal MNDR-E-MI-24474
MNDR hsa-miR-198 Anencephaly MNDR-E-MI-24475
MNDR hsa-miR-198 Precursor cell lymphoblastic leukemia-lymphoma MNDR-E-MI-24476
MNDR hsa-mir-198 Lupus nephritis MNDR-E-MI-24477
MNDR hsa-miR-198 B cell acute lymphoblastic leukemia MNDR-E-MI-24478
MNDR hsa-mir-198 Melanoma and neural system tumor syndrome MNDR-E-MI-24479
MNDR hsa-mir-198 Prostate cancer MNDR-E-MI-24480
MNDR hsa-miR-198 Prostate cancer MNDR-E-MI-24481
MNDR hsa-miR-198 Gastric cancer MNDR-E-MI-24482
MNDR hsa-miR-198 Gastric lymphoma MNDR-E-MI-24483
MNDR hsa-mir-198 Pre-eclampsia MNDR-E-MI-24484
MNDR hsa-miR-198 Alzheimer disease MNDR-E-MI-24485
MNDR hsa-mir-198 Sickle cell diseases MNDR-E-MI-24486
MNDR hsa-miR-198 Intracranial aneurysm MNDR-E-MI-24487
MNDR hsa-mir-198 Carcinoma esophageal MNDR-E-MI-24488
MNDR hsa-miR-198 Dysautonomia familial MNDR-E-MI-24489
MNDR hsa-miR-198 Leukemia MNDR-E-MI-24490
MNDR hsa-miR-198 Huntington disease MNDR-E-MI-24491
MNDR hsa-miR-198 Brain cancer MNDR-E-MI-24492
MNDR hsa-miR-198 Lung cancer MNDR-E-MI-24493
MNDR hsa-mir-198 Lung cancer MNDR-E-MI-24494
MNDR hsa-miR-198 Parkinson disease MNDR-E-MI-24495
MNDR hsa-miR-198 Basal-like breast cancer MNDR-E-MI-24496
MNDR hsa-mir-198 Breast cancer MNDR-E-MI-24497
MNDR hsa-mir-198 Cancer MNDR-E-MI-24498
MNDR hsa-mir-198 Pancreatic cancer MNDR-E-MI-24499
MNDR hsa-miR-198 Pancreatic cancer MNDR-E-MI-24500
MNDR hsa-miR-198 Melanoma MNDR-E-MI-24501
MNDR hsa-miR-198 Nephroblastoma MNDR-E-MI-24502
MNDR hsa-miR-198 Colon cancer MNDR-E-MI-24503
MNDR hsa-miR-198 Ischemic attack transient MNDR-E-MI-24504
MNDR hsa-miR-198 Familial ovarian cancer MNDR-E-MI-24505
MNDR hsa-mir-198 Ovarian cancer MNDR-E-MI-24506
MNDR hsa-miR-198 Kidney cancer MNDR-E-MI-24507
MNDR hsa-mir-198 Glioblastoma MNDR-E-MI-24508
MNDR hsa-miR-198 Glioma MNDR-E-MI-24509
MNDR hsa-mir-198 Glioma MNDR-E-MI-24510
MNDR hsa-miR-198 Amyotrophic lateral sclerosis MNDR-E-MI-24511
MNDR hsa-miR-198 Osteosarcoma MNDR-E-MI-24512
MNDR hsa-mir-198 Osteosarcoma MNDR-E-MI-24513
MNDR hsa-mir-198 Coronary artery disease MNDR-E-MI-24514
MNDR hsa-mir-198 Pancreatic ductal adenocarcinoma MNDR-E-MI-24515
MNDR hsa-miR-198 Hepatocellular cancer MNDR-E-MI-24516
MNDR hsa-miR-198 Uterine cancer MNDR-E-MI-24517
MNDR hsa-miR-198 Lung squamous cell carcinoma MNDR-E-MI-24518
MNDR hsa-miR-198 Lung adenocarcinoma MNDR-E-MI-24519
MNDR hsa-mir-198 Pancreatic adenocarcinoma MNDR-E-MI-24520
MNDR hsa-miR-198 Cholangiocarcinoma MNDR-E-MI-24521
MNDR hsa-miR-198 Esophageal cancer MNDR-E-MI-24522
MNDR hsa-miR-198 Lung small cell carcinoma MNDR-E-MI-24523
MNDR hsa-mir-198 Schizophrenia MNDR-E-MI-24524
MNDR hsa-mir-198 Head and neck squamous cell carcinoma MNDR-E-MI-24525
MNDR hsa-miR-198 T acute lymphoblastic leukemia MNDR-E-MI-24526
MNDR hsa-miR-198 Acute t cell leukemia MNDR-E-MI-24527
MNDR hsa-mir-198 Acquired immunodeficiency syndrome MNDR-E-MI-24528
MNDR hsa-miR-198 Progressive supranuclear palsy MNDR-E-MI-24529
MNDR hsa-mir-198 Carcinoma hepatocellular MNDR-E-MI-24530
MNDR hsa-miR-198 Hepatocellular carcinoma MNDR-E-MI-24531
MNDR hsa-miR-198 Familiar ovarian carcinoma MNDR-E-MI-24532
MNDR hsa-miR-198 B-cell lymphoma MNDR-E-MI-24533
MNDR hsa-miR-198 T-cell leukemia MNDR-E-MI-24534
MNDR hsa-miR-198 Malignant pleural mesothelioma MNDR-E-MI-24535
MNDR hsa-miR-198 Retinoblastoma MNDR-E-MI-24536
MNDR hsa-mir-198 Gastrointestinal system disease MNDR-E-MI-24537
MNDR hsa-mir-198 Hodgkin lymphoma MNDR-E-MI-24538
MNDR hsa-miR-198 Hodgkin lymphoma MNDR-E-MI-24539
MNDR hsa-miR-198 Burkitt lymphoma MNDR-E-MI-24540
MNDR hsa-miR-198 Tonsil cancer MNDR-E-MI-24541
MNDR hsa-mir-198 Systemic lupus erythematosus MNDR-E-MI-24542
MNDR hsa-mir-198 Leukemia acute myeloid MNDR-E-MI-24543
MNDR hsa-mir-198 Colorectal cancer MNDR-E-MI-24544
MNDR hsa-miR-198 Colorectal cancer MNDR-E-MI-24545
MNDR hsa-miR-198 Nasopharynx carcinoma MNDR-E-MI-24546
MNDR hsa-mir-198 Multiple myeloma MNDR-E-MI-24547
MNDR hsa-miR-198 Multiple myeloma MNDR-E-MI-24548
MNDR hsa-miR-198 Acute lymphocytic leukemia MNDR-E-MI-24549
MNDR hsa-mir-198 Lupus vulgaris MNDR-E-MI-24550
MNDR hsa-miR-198 Nasopharyngeal cancer MNDR-E-MI-24551
MNDR hsa-mir-198 Prostatic neoplasms MNDR-E-MI-24552
MNDR hsa-miR-198 Pancreatitis chronic MNDR-E-MI-24553
MNDR hsa-miR-198 Stroke lacunar MNDR-E-MI-24554
MNDR hsa-miR-198 Breast cancer her3+ negative MNDR-E-MI-24555
MNDR hsa-mir-198 Systemic lupus erythematosus susceptibility MNDR-E-MI-24556
RNA Interaction Information
Resource RNA Symbol Species Link RNALocate ID
RNAInter BIRC7 Homo sapiens RR00225394
TOP