Basic Information
| RNALocate ID: | RLID:11000839 |
| RNA Symbol: | hsa-miR-25-3p |
| Localization: | Exosome |
RNA Information
| RNA Name: | hsa-miR-25-3p |
| RNA ID: | miRBase:MIMAT0000081 |
| RNA Category: | miRNA |
| Species: | Homo sapiens |
Localization Information
| PubMed ID: | 22211110 |
| Tissue/Cell Line: | Breast milk |
| Method: | Next-generation RNA sequencing |
|
The expression profile of selected miRNAs in breast milk exosomes. Originally published in Int J Biol Sci. Zhou Q, et al, 2012. Reproduced under the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/) |
|
| Description: | Distribution and characterization of miRNAs in breast milk exosomes. (A) Distribution of pre-miRNAs. Out of 1,424 pre-miRNAs deposited in miRBase 17.0 (blue circle), 87 (6.11%) pre-miRNAs have been designated as immune-related pre-miRNAs based on annotation in the Pathway Central database (SABiosciences, MD, USA). Immune-related pre-miRNAs (59 of 452, 13.05%) are enriched in breast milk exosomes (red circle). χ2 test: Number of immune-related miRNAs and others detected in breast milk exosomes compared with the total entries in miRBase 17.0. (B) Top ten most highly expressed unique miRNAs. Plot of the unique miRNAs (starting from the miRNA with the highest counts, x-axis) versus their cumulative % of the total counts from 602 unique miRNAs detected in breast milk exosomes for each small RNA library. Values are means ± s.d. The dashed horizontal line at 62.3% represents the level of the top ten unique miRNAs and the % of individual miRNAs is marked by the gray line. (C-E) The expression profile of selected miRNAs in breast milk exosomes. (C) 59 immune-related pre-miRNAs; (D) miR-17-92 cluster and paralogous clusters, and (E) ten well-characterized tissue-specific pre-miRNAs. Data are collected from Figure 2. |
Other Subcellular Localization
| RNALocate ID | Localization | Tissue/Cell line | PubMed ID |
| RLID:01001340 | Cytoplasm | Neural progenitor cells | 21363885 |
| RLID:01001341 | Cytoplasm | Breast adenocarcinoma cells (MCF-7)|Cervical adenocarcinoma cells (HeLa) | 24918059 |
| RLID:01001342 | Mitochondrion | Skeletal muscle myoblasts | 21637849 |
| RLID:01001343 | Mitochondrion | Cell line (HEK-293|HeLa) | 22984580 |
| RLID:01001344 | Nucleus | Breast adenocarcinoma cells (MCF-7)|Cervical adenocarcinoma cells (HeLa) | 24918059 |
| RLID:01001345 | Nucleolus | Breast adenocarcinoma cells (MCF-7)|Cervical adenocarcinoma cells (HeLa) | 24918059 |
| RLID:01001346 | Nucleus | Colon adenocarcinoma cells | 20864815 |
| RLID:11000835 | Exosome | Breast cancer cell line (MCF-7) | 20976003 |
| RLID:11000836 | Exosome | Primary dendritic cells|T cell line (J77) | 21505438 |
| RLID:11000837 | Exosome | Renal cancer cells | 21670082 |
| RLID:11000838 | Exosome | Ovarian follicular fluid | 22116803 |
| RLID:11000840 | Exosome | Brain tissue | 23382797 |
| RLID:11000841 | Exosome | Plasma | 23663360 |
| RLID:11000842 | Exosome | Human esophageal cancer cell line (EC9706) | 25184951 |
| RLID:11000843 | Extracellular Vesicle | Liposarcoma cell lines (Lipo224B|Lipo246|Lipo863|LPS141)|Preadipocytes | 28588009 |
| RLID:11000844 | Extracellular vesicle | Plasma | 32498409 |
| RLID:11000845 | Extracellular vesicle | HEK-293T cells | 22849433 |
| RLID:11000846 | Microvesicle | Plasma | 23077538 |
| RLID:11000847 | Microvesicle | Seminal plasma | 23539611 |
| RLID:11000848 | Microvesicle | Hepatoma cells | 23771658 |
| RLID-D:11000017 | Exosome | Blood|B lymphoblastoid cells|Breast milk|Chronic lymphocytic leukemia cells|Colon tissue|Endothelial cells|Epithelial cells|Kidney tissue|Lymphoma tissue|Mast cells|Seminal fluid|Tongue tissue | |
| RLID-D:11000280 | Microvesicle | Blood|Colon cancer cell line (LIM1863)|Fibroblasts|Mesenchymal stem cells|Urine |
ncRNA Disease Information
| Resource | RNA Symbol | Disease | Link |
| MNDR | hsa-miR-25-3p | Splenic marginal zone lymphoma | MNDR-E-MI-32729 |
| MNDR | hsa-miR-25-3p | Multiple sclerosis chronic progressive | MNDR-E-MI-32730 |
| MNDR | hsa-miR-25-3p | Oral squamous cell carcinoma | MNDR-E-MI-32731 |
| MNDR | hsa-miR-25-3p | Large cell neuroendocrine cancer | MNDR-E-MI-32732 |
| MNDR | hsa-miR-25-3p | Medulloblastoma | MNDR-E-MI-32733 |
| MNDR | hsa-miR-25-3p | High-grade serous ovarian carcinoma | MNDR-E-MI-32734 |
| MNDR | hsa-miR-25-3p | Uterine corpus endometrial carcinoma | MNDR-E-MI-32735 |
| MNDR | hsa-miR-25-3p | Lymphoma | MNDR-E-MI-32736 |
| MNDR | hsa-miR-25-3p | Lymphoma non-hodgkin | MNDR-E-MI-32737 |
| MNDR | hsa-miR-25-3p | Estrogen-receptor positive breast cancer | MNDR-E-MI-32738 |
| MNDR | hsa-miR-25-3p | Estrogen-receptor negative breast cancer | MNDR-E-MI-32739 |
| MNDR | hsa-miR-25-3p | Progesterone-receptor positive breast cancer | MNDR-E-MI-32740 |
| MNDR | hsa-miR-25-3p | Progesterone-receptor negative breast cancer | MNDR-E-MI-32741 |
| MNDR | hsa-miR-25-3p | Her2-receptor positive breast cancer | MNDR-E-MI-32742 |
| MNDR | hsa-miR-25-3p | Anaplastic thyroid carcinoma | MNDR-E-MI-32743 |
| MNDR | hsa-miR-25-3p | Prostate cancer | MNDR-E-MI-32744 |
| MNDR | hsa-miR-25-3p | Gastric cancer | MNDR-E-MI-32745 |
| MNDR | hsa-miR-25-3p | Gastric lymphoma | MNDR-E-MI-32746 |
| MNDR | hsa-miR-25-3p | Alzheimer disease | MNDR-E-MI-32747 |
| MNDR | hsa-miR-25-3p | Intracranial aneurysm | MNDR-E-MI-32748 |
| MNDR | hsa-miR-25-3p | Bladder cancer | MNDR-E-MI-32749 |
| MNDR | hsa-miR-25-3p | Esophageal carcinoma | MNDR-E-MI-32750 |
| MNDR | hsa-miR-25-3p | Dysautonomia familial | MNDR-E-MI-32751 |
| MNDR | hsa-miR-25-3p | Malaria | MNDR-E-MI-32752 |
| MNDR | hsa-miR-25-3p | Leukemia | MNDR-E-MI-32753 |
| MNDR | hsa-miR-25-3p | Cardiovascular disease | MNDR-E-MI-32754 |
| MNDR | hsa-miR-25-3p | Moyamoya disease | MNDR-E-MI-32755 |
| MNDR | hsa-miR-25-3p | Lung cancer | MNDR-E-MI-32756 |
| MNDR | hsa-miR-25-3p | Down syndrome | MNDR-E-MI-32757 |
| MNDR | hsa-miR-25-3p | Parkinson disease | MNDR-E-MI-32758 |
| MNDR | hsa-miR-25-3p | Machado-joseph disease | MNDR-E-MI-32759 |
| MNDR | hsa-miR-25-3p | Basal-like breast cancer | MNDR-E-MI-32760 |
| MNDR | hsa-miR-25-3p | Pancreatic cancer | MNDR-E-MI-32761 |
| MNDR | hsa-miR-25-3p | Melanoma | MNDR-E-MI-32762 |
| MNDR | hsa-miR-25-3p | Lesch-nyhan syndrome | MNDR-E-MI-32763 |
| MNDR | hsa-miR-25-3p | Atherosclerosis | MNDR-E-MI-32764 |
| MNDR | hsa-miR-25-3p | Rectum adenocarcinoma | MNDR-E-MI-32765 |
| MNDR | hsa-miR-25-3p | Nephroblastoma | MNDR-E-MI-32766 |
| MNDR | hsa-miR-25-3p | Colon cancer | MNDR-E-MI-32767 |
| MNDR | hsa-miR-25-3p | Ischemic attack transient | MNDR-E-MI-32768 |
| MNDR | hsa-miR-25-3p | Colon adenocarcinoma | MNDR-E-MI-32769 |
| MNDR | hsa-miR-25-3p | Multiple sclerosis relapsing-remitting | MNDR-E-MI-32770 |
| MNDR | hsa-miR-25-3p | Familial ovarian cancer | MNDR-E-MI-32771 |
| MNDR | hsa-miR-25-3p | Prostate adenocarcinoma | MNDR-E-MI-32772 |
| MNDR | hsa-miR-25-3p | Iga glomerulonephritis | MNDR-E-MI-32773 |
| MNDR | hsa-miR-25-3p | Invasive ductal carcinoma | MNDR-E-MI-32774 |
| MNDR | hsa-miR-25-3p | Glioblastoma | MNDR-E-MI-32775 |
| MNDR | hsa-miR-25-3p | Astrocytoma | MNDR-E-MI-32776 |
| MNDR | hsa-miR-25-3p | Glioma | MNDR-E-MI-32777 |
| MNDR | hsa-miR-25-3p | Chronic obstructive pulmonary disease | MNDR-E-MI-32778 |
| MNDR | hsa-miR-25-3p | Amyotrophic lateral sclerosis | MNDR-E-MI-32779 |
| MNDR | hsa-miR-25-3p | Temporal lobe epilepsy | MNDR-E-MI-32780 |
| MNDR | hsa-miR-25-3p | Coronary artery disease | MNDR-E-MI-32781 |
| MNDR | hsa-miR-25-3p | Liver cancer | MNDR-E-MI-32782 |
| MNDR | hsa-miR-25-3p | Uterine cancer | MNDR-E-MI-32783 |
| MNDR | hsa-miR-25-3p | Cervical adenocarcinoma | MNDR-E-MI-32784 |
| MNDR | hsa-miR-25-3p | Gastric adenocarcinoma | MNDR-E-MI-32785 |
| MNDR | hsa-miR-25-3p | Cervical squamous cell carcinoma | MNDR-E-MI-32786 |
| MNDR | hsa-miR-25-3p | Lung squamous cell carcinoma | MNDR-E-MI-32787 |
| MNDR | hsa-miR-25-3p | Lung adenocarcinoma | MNDR-E-MI-32788 |
| MNDR | hsa-miR-25-3p | Thyroid carcinoma | MNDR-E-MI-32789 |
| MNDR | hsa-miR-25-3p | Ovarian carcinoma | MNDR-E-MI-32790 |
| MNDR | hsa-miR-25-3p | Bladder urothelial carcinoma | MNDR-E-MI-32791 |
| MNDR | hsa-miR-25-3p | Pancreatic adenocarcinoma | MNDR-E-MI-32792 |
| MNDR | hsa-miR-25-3p | Myasthenia gravis autoimmune experimental | MNDR-E-MI-32793 |
| MNDR | hsa-miR-25-3p | Carcinoma renal cell | MNDR-E-MI-32794 |
| MNDR | hsa-miR-25-3p | Kidney renal papillary cell carcinoma | MNDR-E-MI-32795 |
| MNDR | hsa-miR-25-3p | Clear cell renal cell carcinoma | MNDR-E-MI-32796 |
| MNDR | hsa-miR-25-3p | Adenocarcinoma of esophagus | MNDR-E-MI-32797 |
| MNDR | hsa-miR-25-3p | Cholangiocarcinoma | MNDR-E-MI-32798 |
| MNDR | hsa-miR-25-3p | Esophageal cancer | MNDR-E-MI-32799 |
| MNDR | hsa-miR-25-3p | Liver cirrhosis | MNDR-E-MI-32800 |
| MNDR | hsa-miR-25-3p | Small cell lung cancer | MNDR-E-MI-32801 |
| MNDR | hsa-miR-25-3p | Stomach carcinoma | MNDR-E-MI-32802 |
| MNDR | hsa-miR-25-3p | Head and neck squamous cell carcinoma | MNDR-E-MI-32803 |
| MNDR | hsa-miR-25-3p | Hepatocellular carcinoma | MNDR-E-MI-32804 |
| MNDR | hsa-miR-25-3p | Familiar ovarian carcinoma | MNDR-E-MI-32805 |
| MNDR | hsa-miR-25-3p | B-cell lymphoma | MNDR-E-MI-32806 |
| MNDR | hsa-miR-25-3p | Rheumatoid arthritis | MNDR-E-MI-32807 |
| MNDR | hsa-miR-25-3p | T-cell leukemia | MNDR-E-MI-32808 |
| MNDR | hsa-miR-25-3p | Retinoblastoma | MNDR-E-MI-32809 |
| MNDR | hsa-miR-25-3p | Barrett's adenocarcinoma | MNDR-E-MI-32810 |
| MNDR | hsa-miR-25-3p | Hodgkin lymphoma | MNDR-E-MI-32811 |
| MNDR | hsa-miR-25-3p | Burkitt lymphoma | MNDR-E-MI-32812 |
| MNDR | hsa-miR-25-3p | Tonsil cancer | MNDR-E-MI-32813 |
| MNDR | hsa-miR-25-3p | Colorectal cancer | MNDR-E-MI-32814 |
| MNDR | hsa-miR-25-3p | Nasopharynx carcinoma | MNDR-E-MI-32815 |
| MNDR | hsa-miR-25-3p | Multiple myeloma | MNDR-E-MI-32816 |
| MNDR | hsa-miR-25-3p | Ovarian epithelial cancer | MNDR-E-MI-32817 |
| MNDR | hsa-miR-25-3p | Esophageal squamous cell carcinoma | MNDR-E-MI-32818 |
| MNDR | hsa-miR-25-3p | Ependymoma | MNDR-E-MI-32819 |
| MNDR | hsa-miR-25-3p | Nasopharyngeal cancer | MNDR-E-MI-32820 |
| MNDR | hsa-miR-25-3p | Prostatic neoplasms | MNDR-E-MI-32821 |
| MNDR | hsa-miR-25-3p | Sarcopenia | MNDR-E-MI-32822 |
| MNDR | hsa-miR-25-3p | Stroke lacunar | MNDR-E-MI-32823 |
| MNDR | hsa-miR-25-3p | Barrett's carcinogenesis | MNDR-E-MI-32824 |
| MNDR | hsa-miR-25-3p | Breast cancer her3+ negative | MNDR-E-MI-32825 |
| MNDR | hsa-miR-25-3p | Duke C | MNDR-E-MI-32826 |
| MNDR | hsa-miR-25-3p | Solid-pseudopapillary neoplasm of pancreas | MNDR-E-MI-32827 |
RNA Interaction Information
| Resource | RNA Symbol | Species | Link | RNALocate ID |
| RNAInter | ABHD13 | Homo sapiens | RR00025339 |
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