Basic Information
RNALocate ID: RLID:00007449
RNA Symbol: TUBB
Localization: Ribosome-free cytosol
Localization from RNA-seq Dataset:  
RNA Information
RNA Name: TUBB
RNA ID: NCBI:203068|Ensembl:ENSG00000196230
RNA Category: mRNA
Species: Homo sapiens
Alias: CDCBM6|CSCSC1|M40|OK/SW-cl.56|TUBB1|TUBB5
Sequence:
Localization Information
PubMed ID: 24393600
Tissue/Cell Line: Colon cancer cells
Method: Next-generation RNA sequencing
Description: The RNA composition of the subcellular fractions differs significantly from each other, but lncRNAs are found in all locations. A subset of specific lncRNAs is enriched in the nucleus but surprisingly the majority is enriched in the cytosol and in ribosomal fractions. The ribosomal enriched lncRNAs include H19 and TUG1. Most studies on lncRNAs have focused on the regulatory function of these transcripts in the nucleus. We demonstrate that only a minority of all lncRNAs are nuclear enriched. Our findings suggest that many lncRNAs may have a function in cytoplasmic processes, and in particular in ribosome complexes. Data were collected from additional file 5.Overall, we consider clusters I, II and III as enriched in the nucleus; IV and V as enriched in the ribosome-free cytosol; and VI, VII, VIII, IX and X as enriched in the ribosomes.
Homology Information
RNA Symbol Gene ID Species Detail
tubb5 NCBI:386701 Danio rerio Go to
Other Subcellular Localization
RNALocate ID Localization Tissue/Cell line PubMed ID
RLID:00007448 Cytosol Human myelogenous leukemia cell line (K-562) 21613539
RLID-D:00001377 Chromatin K562 cells
RLID-D:00008737 Cytosol K562 cells
RLID-D:00014102 Insoluble cytoplasm K562 cells
RLID-D:00019542 Nucleolus K562 cells
RLID-D:00025733 Nucleoplasm K562 cells
RLID-D:00033558 Nucleus HCC cell line (HepG2)|HeLa-S3 cells|K562 cells
RLID-D:10003902 Exosome Blood
RNA Interaction Information
Resource RNA Symbol Species Link RNALocate ID
RNAInter SNHG16 Homo sapiens RR01337793
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