The Detail page: representing the detail information for virus-host related ncRNA interaction;
The Binding page: representing the predicted binding sites.
The Network page: representing the interaction sub-network of interacting ncRNA/Interactor.
- Detail
- Binding
- Network
Detail: | |
Vhid: | VHID00005703 |
---|---|
Virus: | Human immunodeficiency virus 1(HIV-1) |
Host Species: | Homo sapiens |
ncRNA Source: | Virus |
ncRNA Category: | miRNA |
ncRNA Symbol: | hiv1-mir-H1 |
Tissue: | Human blood mononuclear cells |
Expression Direction of ncRNA: | - |
Interactor in Virus or Host: | Host |
Interactor Category: | Protein |
Interactor Symbol: | PAWR |
Expression Direction of Interactor: | Downregulation |
Validated Method: | FACS analysis, trypan-blue dye exclusion method, microarray analysis, Real-Time PCR, Bioinformatic analysis. |
PMID: | 19082544 |
Detailed Description: | Such a study revealed that this miRNA-induced knockdown of AATF gene, within normal human blood mononuclear cells, was responsible for the suppression of genes coding for Bcl-2, c-myc, Par-4 and Dicer. |
The 'First Node' or 'Second Node' option represents the sub-network of interacting ncRNA/Interactor with the first or second interaction node,
the 'Both the Nodes' option represents the sub-network of interacting ncRNA/Interactor with both of interaction nodes.
The 'First Neighbour' represents the sub-network of direct interacting with the center node,
the 'Second Neighbour' represents the sub-network of direct or second step interacting with the center node.
Interaction sub-network based on the two nodes of this interaction may help the researchers represents all interacting partners immediately.