• Detail
  • Binding
  • Network
Detail:
Vhid: VHID00005703
Virus: Human immunodeficiency virus 1(HIV-1)
Host Species: Homo sapiens
ncRNA Source: Virus
ncRNA Category: miRNA
ncRNA Symbol: hiv1-mir-H1
Tissue: Human blood mononuclear cells
Expression Direction of ncRNA: -
Interactor in Virus or Host: Host
Interactor Category: Protein
Interactor Symbol: PAWR
Expression Direction of Interactor: Downregulation
Validated Method: FACS analysis, trypan-blue dye exclusion method, microarray analysis, Real-Time PCR, Bioinformatic analysis.
PMID: 19082544
Detailed Description: Such a study revealed that this miRNA-induced knockdown of AATF gene, within normal human blood mononuclear cells, was responsible for the suppression of genes coding for Bcl-2, c-myc, Par-4 and Dicer.
Select the transcript of gene PAWR(Par-4) interacted with hiv1-mir-H1
The ncRNA Symbol: hiv1-mir-H1 Transcript of PAWR(Par-4):
Visualization:
Select the center nodes: First Node Second Node Both the Nodes
Select the Level of Neighbour: First Neighbour Second Neighbour
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The 'First Node' or 'Second Node' option represents the sub-network of interacting ncRNA/Interactor with the first or second interaction node, the 'Both the Nodes' option represents the sub-network of interacting ncRNA/Interactor with both of interaction nodes.
The 'First Neighbour' represents the sub-network of direct interacting with the center node, the 'Second Neighbour' represents the sub-network of direct or second step interacting with the center node. Interaction sub-network based on the two nodes of this interaction may help the researchers represents all interacting partners immediately.

The Detail page: representing the detail information for virus-host related ncRNA interaction;
The Binding page: representing the predicted binding sites.
The Network page: representing the interaction sub-network of interacting ncRNA/Interactor.