The Detail page: representing the detail information for virus-host related ncRNA interaction;
The Binding page: representing the predicted binding sites.
The Network page: representing the interaction sub-network of interacting ncRNA/Interactor.
- Detail
- Binding
- Network
Detail: | |
Vhid: | VHID00005604 |
---|---|
Virus: | Herpes simplex virus 1(HSV-1) |
Host Species: | Homo sapiens |
ncRNA Source: | Virus |
ncRNA Category: | miRNA |
ncRNA Symbol: | hsv1-mir-LAT |
Tissue: | Sensory neurons |
Expression Direction of ncRNA: | - |
Interactor in Virus or Host: | Host |
Interactor Category: | Protein |
Interactor Symbol: | TGFB1 |
Expression Direction of Interactor: | Downregulation |
Validated Method: | Reporter assays,RT-PCR,Northern blotting and Western analysis. |
PMID: | 16738545 |
Detailed Description: | miR-LAT exerts its anti-apoptotic effect by downregulation of transforming growth factor(TGF)-beta 1 and SMAD3 expression, both of which are functionally linked in the TGF-beta pathway. |
The 'First Node' or 'Second Node' option represents the sub-network of interacting ncRNA/Interactor with the first or second interaction node,
the 'Both the Nodes' option represents the sub-network of interacting ncRNA/Interactor with both of interaction nodes.
The 'First Neighbour' represents the sub-network of direct interacting with the center node,
the 'Second Neighbour' represents the sub-network of direct or second step interacting with the center node.
Interaction sub-network based on the two nodes of this interaction may help the researchers represents all interacting partners immediately.