The Detail page: representing the detail information for virus-host related ncRNA interaction;
The Binding page: representing the predicted binding sites.
The Network page: representing the interaction sub-network of interacting ncRNA/Interactor.
- Detail
- Binding
- Network
| Detail: | |
| Vhid: | VHID00000018 |
|---|---|
| Virus: | Epstein-Barr virus(EBV) |
| Host Species: | Homo sapiens |
| ncRNA Source: | Virus |
| ncRNA Category: | LncRNA |
| ncRNA Symbol: | EBER1 |
| Tissue: | B cells |
| Expression Direction of ncRNA: | - |
| Interactor in Virus or Host: | Host |
| Interactor Category: | Protein |
| Interactor Symbol: | RPL22 |
| Expression Direction of Interactor: | - |
| Validated Method: | Electrophoretic mobility-shift assays(EMSAs). |
| PMID: | 16556938 |
| Detailed Description: | Multiple domains of EBER 1, an Epstein-Barr virus noncoding RNA, recruit human ribosomal protein L22. Here we present in vitro binding studies using purified RNAs and recombinant proteins. Electrophoretic mobility-shift assays(EMSAs) show that recombinant L22(rL22) and maltose-binding protein(MBP)-tagged L22 protein bind EBER 1 in vitro, both forming three specific protein-dependent mobility shifts. |
The 'First Node' or 'Second Node' option represents the sub-network of interacting ncRNA/Interactor with the first or second interaction node,
the 'Both the Nodes' option represents the sub-network of interacting ncRNA/Interactor with both of interaction nodes.
The 'First Neighbour' represents the sub-network of direct interacting with the center node,
the 'Second Neighbour' represents the sub-network of direct or second step interacting with the center node.
Interaction sub-network based on the two nodes of this interaction may help the researchers represents all interacting partners immediately.