The Detail page: representing the detail information for virus-host related ncRNA interaction;
The Network page: representing the interaction sub-network of interacting ncRNA/Interactor.
- Detail
- Binding
- Network
Detail: | |
Vhid: | HVID00011998 |
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Virus: | Dengue virus(DENV) |
Host Species: | Aedes albopictus |
ncRNA Source: | Host |
ncRNA Category: | miRNA |
ncRNA Symbol: | miR-252 |
Tissue: | Ae. albopictus C6/36 cellline |
Expression Direction of ncRNA: | Upregulation |
Interactor in Virus or Host: | Virus |
Interactor Category: | Protein |
Interactor Symbol: | E |
Expression Direction of Interactor: | Downregulation |
Validated Method: | luciferase activity of a luciferase reporter |
PMID: | 25025105 |
Detailed Description: | Transfection with miR-252 inhibitor resulted in the increase of DENV-2 RNA copies and the up-regulation of DENV-2 envelop protein(E protein) expression, whereas over expression of miR-252 with its mimic decreased DENV RNA copies and the down-regulation of E protein expression. |
The 'First Node' or 'Second Node' option represents the sub-network of interacting ncRNA/Interactor with the first or second interaction node,
the 'Both the Nodes' option represents the sub-network of interacting ncRNA/Interactor with both of interaction nodes.
The 'First Neighbour' represents the sub-network of direct interacting with the center node,
the 'Second Neighbour' represents the sub-network of direct or second step interacting with the center node.
Interaction sub-network based on the two nodes of this interaction may help the researchers represents all interacting partners immediately.