The Detail page: representing the detail information for virus-host related ncRNA interaction;
The Binding page: representing the predicted binding sites.
The Network page: representing the interaction sub-network of interacting ncRNA/Interactor.
- Detail
- Binding
- Network
Detail: | |
Vhid: | HVID00011965 |
---|---|
Virus: | Human papillomavirus(HPV) |
Host Species: | Homo sapiens |
ncRNA Source: | Host |
ncRNA Category: | miRNA |
ncRNA Symbol: | hsa-mir-25 |
Tissue: | organotypic raft cultures of foreskin and vaginal keratinocytes |
Expression Direction of ncRNA: | Upregulation |
Interactor in Virus or Host: | Virus |
Interactor Category: | Protein |
Interactor Symbol: | E7 |
Expression Direction of Interactor: | - |
Validated Method: | RT-qPCR. |
PMID: | 24591631 |
Detailed Description: | As expected, E6 decreased the expression of miR-34a, whereas E7 did not. In contrast, HPV18 E7 significantly increased the expression of miR-25, whereas HPV18 E6 had no effect. |
The 'First Node' or 'Second Node' option represents the sub-network of interacting ncRNA/Interactor with the first or second interaction node,
the 'Both the Nodes' option represents the sub-network of interacting ncRNA/Interactor with both of interaction nodes.
The 'First Neighbour' represents the sub-network of direct interacting with the center node,
the 'Second Neighbour' represents the sub-network of direct or second step interacting with the center node.
Interaction sub-network based on the two nodes of this interaction may help the researchers represents all interacting partners immediately.