The Detail page: representing the detail information for virus-host related ncRNA interaction;
The Binding page: representing the predicted binding sites.
The Network page: representing the interaction sub-network of interacting ncRNA/Interactor.
- Detail
- Binding
- Network
Detail: | |
Vhid: | HVID00011929 |
---|---|
Virus: | Human immunodeficiency virus 1(HIV-1) |
Host Species: | Rattus norvegicus |
ncRNA Source: | Host |
ncRNA Category: | miRNA |
ncRNA Symbol: | rno-let-7e |
Tissue: | rat primary cortical neurons |
Expression Direction of ncRNA: | Downregulation |
Interactor in Virus or Host: | Virus |
Interactor Category: | Protein |
Interactor Symbol: | tat |
Expression Direction of Interactor: | - |
Validated Method: | - |
PMID: | 21786074 |
Detailed Description: | Eletto and colleagues reported that a group of six miRNAs (374, 128a, 128b, 100, 25, and 99a) were upregulated and seven miRNAs (let-7e, 298, let-7f, let-7c, let-7b, 320, and 214) were downregulated by Tat in rat primary cortical neurons. Among these, miR-128a has been found to be enriched in the brain, preferentially in the mature neurons. |
The 'First Node' or 'Second Node' option represents the sub-network of interacting ncRNA/Interactor with the first or second interaction node,
the 'Both the Nodes' option represents the sub-network of interacting ncRNA/Interactor with both of interaction nodes.
The 'First Neighbour' represents the sub-network of direct interacting with the center node,
the 'Second Neighbour' represents the sub-network of direct or second step interacting with the center node.
Interaction sub-network based on the two nodes of this interaction may help the researchers represents all interacting partners immediately.