The Detail page: representing the detail information for virus-host related ncRNA interaction;
The Binding page: representing the predicted binding sites.
The Network page: representing the interaction sub-network of interacting ncRNA/Interactor.
- Detail
- Binding
- Network
| Detail: | |
| Vhid: | HVID00011789 |
|---|---|
| Virus: | Epstein-Barr virus(EBV) |
| Host Species: | Homo sapiens |
| ncRNA Source: | Host |
| ncRNA Category: | miRNA |
| ncRNA Symbol: | hsa-mir-20b |
| Tissue: | EBV B95-8 LCLs and type III BL cells |
| Expression Direction of ncRNA: | - |
| Interactor in Virus or Host: | Virus |
| Interactor Category: | Protein |
| Interactor Symbol: | BHRF1 |
| Expression Direction of Interactor: | - |
| Validated Method: | Western blot analysis, PAR-CLIP, qRT-PCR for RISC-associated BHRF1 mRNAs,Luciferase reporter assays. |
| PMID: | 24257599 |
| Detailed Description: | Our analysis revealed binding sites for several cellular miRNAs, particularly the mycregulated miR-17/20/106 family, in the LMP1 and BHRF1 3'UTRs (27).EBV LMP1 and BHRF1 mRNAs are cotargeted by both viral and cellular miRNAs, such as EBV BART miRNAs and the miR-17/20/106 family, in EBV B95-8 LCLs and type III BL cells. |
The 'First Node' or 'Second Node' option represents the sub-network of interacting ncRNA/Interactor with the first or second interaction node,
the 'Both the Nodes' option represents the sub-network of interacting ncRNA/Interactor with both of interaction nodes.
The 'First Neighbour' represents the sub-network of direct interacting with the center node,
the 'Second Neighbour' represents the sub-network of direct or second step interacting with the center node.
Interaction sub-network based on the two nodes of this interaction may help the researchers represents all interacting partners immediately.