The Detail page: representing the detail information for virus-host related ncRNA interaction;
The Binding page: representing the predicted binding sites.
The Network page: representing the interaction sub-network of interacting ncRNA/Interactor.
- Detail
- Binding
- Network
| Detail: | |
| Vhid: | HVID00011767 |
|---|---|
| Virus: | Adeno-associated virus(AAV) |
| Host Species: | Mus musculus |
| ncRNA Source: | Host |
| ncRNA Category: | miRNA |
| ncRNA Symbol: | mmu-mir-122 |
| Tissue: | Liver cells |
| Expression Direction of ncRNA: | - |
| Interactor in Virus or Host: | Virus |
| Interactor Category: | Protein |
| Interactor Symbol: | E1A |
| Expression Direction of Interactor: | Downregulation |
| Validated Method: | Luciferase reporter, Real time (quantitative) PCR (Q-PCR). |
| PMID: | 19461878 |
| Detailed Description: | Imaging versions of these viruses, produced by fusing E1A with luciferase, showed that inclusion of mir-122 binding sites caused up to 80-fold decreased hepatic expression of E1A following intravenous delivery to mice. |
The 'First Node' or 'Second Node' option represents the sub-network of interacting ncRNA/Interactor with the first or second interaction node,
the 'Both the Nodes' option represents the sub-network of interacting ncRNA/Interactor with both of interaction nodes.
The 'First Neighbour' represents the sub-network of direct interacting with the center node,
the 'Second Neighbour' represents the sub-network of direct or second step interacting with the center node.
Interaction sub-network based on the two nodes of this interaction may help the researchers represents all interacting partners immediately.