The Detail page: representing the detail information for virus-host related ncRNA interaction;
The Network page: representing the interaction sub-network of interacting ncRNA/Interactor.
- Detail
- Binding
- Network
| Detail: | |
| Vhid: | HHID00011745 |
|---|---|
| Virus: | Simian immunodeficiency virus(SIV) |
| Host Species: | Simian |
| ncRNA Source: | Host |
| ncRNA Category: | miRNA |
| ncRNA Symbol: | miR-142-5p |
| Tissue: | HEK293T cells |
| Expression Direction of ncRNA: | Upregulation |
| Interactor in Virus or Host: | Host |
| Interactor Category: | Protein |
| Interactor Symbol: | SIRT1 |
| Expression Direction of Interactor: | Downregulation |
| Validated Method: | Luciferase reporter assays. |
| PMID: | 23752207 |
| Detailed Description: | qRT-PCR revealed up-regulation of miR-142-3p (6.4-fold) and -5p (3.9-fold) and down-regulation of SIRT1 (33-fold) in macrophages/microglia from animals with SIVE. |
The 'First Node' or 'Second Node' option represents the sub-network of interacting ncRNA/Interactor with the first or second interaction node,
the 'Both the Nodes' option represents the sub-network of interacting ncRNA/Interactor with both of interaction nodes.
The 'First Neighbour' represents the sub-network of direct interacting with the center node,
the 'Second Neighbour' represents the sub-network of direct or second step interacting with the center node.
Interaction sub-network based on the two nodes of this interaction may help the researchers represents all interacting partners immediately.