The Detail page: representing the detail information for virus-host related ncRNA interaction;
The Binding page: representing the predicted binding sites.
The Network page: representing the interaction sub-network of interacting ncRNA/Interactor.
- Detail
- Binding
- Network
| Detail: | |
| Vhid: | HHID00011604 |
|---|---|
| Virus: | Influenza A virus(infA) |
| Host Species: | Homo sapiens |
| ncRNA Source: | Host |
| ncRNA Category: | miRNA |
| ncRNA Symbol: | hsa-mir-132 |
| Tissue: | Lung cell lines |
| Expression Direction of ncRNA: | - |
| Interactor in Virus or Host: | Host |
| Interactor Category: | mRNA |
| Interactor Symbol: | NAP1L1 |
| Expression Direction of Interactor: | Downregulation |
| Validated Method: | Reverse Transcription, Real-time PCR, Immunoblotting, RNA Purification, Indirect Immunofluorescence, MicroRNA Microarray Analysis, Gene Expression Profiling and Pathway Analysis, and miRNA Analysis. |
| PMID: | 22822053 |
| Detailed Description: | Table2 Abundance ofmiRNA targetedmRNAs during influenza A virus infection. However, data analysis identi-fied 36 genes that were differentially expressed during infection in the presence of miRNA mimics: decreased expression was Observed for 26 genes, whereas 10 genes increased expression (greater than 1.5-fold threshold, see Table 2).Examination of miRNA abundance in human lung cell lines revealed endogenous miRNAs, including miR-7, miR-132, miR-146a, miR-187, miR-200c, and miR-1275.Gene expression profiling identified 26 cellular mRNAs targeted by these miRNAs, including IRAK1, MAPK3, and other components of innate immune signaling systems. |
The 'First Node' or 'Second Node' option represents the sub-network of interacting ncRNA/Interactor with the first or second interaction node,
the 'Both the Nodes' option represents the sub-network of interacting ncRNA/Interactor with both of interaction nodes.
The 'First Neighbour' represents the sub-network of direct interacting with the center node,
the 'Second Neighbour' represents the sub-network of direct or second step interacting with the center node.
Interaction sub-network based on the two nodes of this interaction may help the researchers represents all interacting partners immediately.