The Detail page: representing the detail information for virus-host related ncRNA interaction;
The Binding page: representing the predicted binding sites.
The Network page: representing the interaction sub-network of interacting ncRNA/Interactor.
- Detail
- Binding
- Network
| Detail: | |
| Vhid: | HHID00011573 |
|---|---|
| Virus: | Influenza A virus H3N2(H3N2) |
| Host Species: | Homo sapiens |
| ncRNA Source: | Host |
| ncRNA Category: | miRNA |
| ncRNA Symbol: | hsa-mir-146a |
| Tissue: | Lung epithelial cells |
| Expression Direction of ncRNA: | Upregulation |
| Interactor in Virus or Host: | Host |
| Interactor Category: | Protein |
| Interactor Symbol: | FLOT2 |
| Expression Direction of Interactor: | |
| Validated Method: | RT-qPCR. |
| PMID: | 23343627 |
| Detailed Description: | In this study, we performed miRNA global profiling in human lung epithelial cells(A549) infected by two different subtypes of human influenza A viruses(H1N1 and H3N2). Among the five miRNA hits, the only upregulated miRNA in response to influenza infection corresponded to miR-146a.Table 1. Gene expression data for the 16 miR-146a target genes down-modulated after influenza infection. |
The 'First Node' or 'Second Node' option represents the sub-network of interacting ncRNA/Interactor with the first or second interaction node,
the 'Both the Nodes' option represents the sub-network of interacting ncRNA/Interactor with both of interaction nodes.
The 'First Neighbour' represents the sub-network of direct interacting with the center node,
the 'Second Neighbour' represents the sub-network of direct or second step interacting with the center node.
Interaction sub-network based on the two nodes of this interaction may help the researchers represents all interacting partners immediately.