The Detail page: representing the detail information for virus-host related ncRNA interaction;
The Binding page: representing the predicted binding sites.
The Network page: representing the interaction sub-network of interacting ncRNA/Interactor.
- Detail
- Binding
- Network
Detail: | |
Vhid: | HHID00011232 |
---|---|
Virus: | Human T-cell leukemia virus 1(HTLV-1) |
Host Species: | Homo sapiens |
ncRNA Source: | Host |
ncRNA Category: | miRNA |
ncRNA Symbol: | hsa-mir-31 |
Tissue: | - |
Expression Direction of ncRNA: | Downregulation |
Interactor in Virus or Host: | Host |
Interactor Category: | Protein |
Interactor Symbol: | MAP3K14 |
Expression Direction of Interactor: | Upregulation |
Validated Method: | RT-PCR. |
PMID: | 23189820 |
Detailed Description: | Some studies have demonstrated that some deregulations of miRNA are involved in the pathogenesis of HTLV-1. Furthermore, global analyses of ATL patient samples have provided a conceptual progress that Polycomb family induces miR-31 silencing, resulting in overexpression of NF-kappaB inducing kinase(NIK) following NF-kappaB activation. |
The 'First Node' or 'Second Node' option represents the sub-network of interacting ncRNA/Interactor with the first or second interaction node,
the 'Both the Nodes' option represents the sub-network of interacting ncRNA/Interactor with both of interaction nodes.
The 'First Neighbour' represents the sub-network of direct interacting with the center node,
the 'Second Neighbour' represents the sub-network of direct or second step interacting with the center node.
Interaction sub-network based on the two nodes of this interaction may help the researchers represents all interacting partners immediately.