The Detail page: representing the detail information for virus-host related ncRNA interaction;
The Binding page: representing the predicted binding sites.
The Network page: representing the interaction sub-network of interacting ncRNA/Interactor.
- Detail
- Binding
- Network
| Detail: | |
| Vhid: | HHID00011229 |
|---|---|
| Virus: | Herpes simplex virus 1(HSV-1) |
| Host Species: | Homo sapiens |
| ncRNA Source: | Host |
| ncRNA Category: | LncRNA |
| ncRNA Symbol: | NEAT1 |
| Tissue: | - |
| Expression Direction of ncRNA: | - |
| Interactor in Virus or Host: | Host |
| Interactor Category: | Protein |
| Interactor Symbol: | CXCL8 |
| Expression Direction of Interactor: | Upregulation |
| Validated Method: | - |
| PMID: | 24507715 |
| Detailed Description: | Here we show that nuclear enriched abundant transcript 1 (NEAT1), an essential LncRNA for the formation of nuclear body paraspeckles, is induced by influenza virus and herpes simplex virus infection as well as by Toll-like receptor3-p38 pathway-triggered poly I:C stimulation, resulting in excess formation of paraspeckles.We found that NEAT1 facilitates the expression of antiviral genes including cytokines such as interleukin-8 (IL8). |
The 'First Node' or 'Second Node' option represents the sub-network of interacting ncRNA/Interactor with the first or second interaction node,
the 'Both the Nodes' option represents the sub-network of interacting ncRNA/Interactor with both of interaction nodes.
The 'First Neighbour' represents the sub-network of direct interacting with the center node,
the 'Second Neighbour' represents the sub-network of direct or second step interacting with the center node.
Interaction sub-network based on the two nodes of this interaction may help the researchers represents all interacting partners immediately.