The Detail page: representing the detail information for virus-host related ncRNA interaction;
The Binding page: representing the predicted binding sites.
The Network page: representing the interaction sub-network of interacting ncRNA/Interactor.
- Detail
- Binding
- Network
| Detail: | |
| Vhid: | HHID00011226 |
|---|---|
| Virus: | Hepatitis C virus(HCV) |
| Host Species: | Rattus norvegicus |
| ncRNA Source: | Host |
| ncRNA Category: | miRNA |
| ncRNA Symbol: | rno-mir-122 |
| Tissue: | cultured rat cells |
| Expression Direction of ncRNA: | - |
| Interactor in Virus or Host: | Host |
| Interactor Category: | Protein |
| Interactor Symbol: | Slc7a1 |
| Expression Direction of Interactor: | Downregulation |
| Validated Method: | Mutational analyses. |
| PMID: | 17381319 |
| Detailed Description: | CAT-1 activity is absent in the quiescent liver, but it is increased in primary or transformed hepatocytes.Incontrast, interaction of miR-122 with the 3'-noncoding region(3'NCR) of the cellularmRNA encoding the cationic amino acid transporter CAT-1 resulted in the down-regulation of CAT-1 protein abundance. |
The 'First Node' or 'Second Node' option represents the sub-network of interacting ncRNA/Interactor with the first or second interaction node,
the 'Both the Nodes' option represents the sub-network of interacting ncRNA/Interactor with both of interaction nodes.
The 'First Neighbour' represents the sub-network of direct interacting with the center node,
the 'Second Neighbour' represents the sub-network of direct or second step interacting with the center node.
Interaction sub-network based on the two nodes of this interaction may help the researchers represents all interacting partners immediately.