The Detail page: representing the detail information for virus-host related ncRNA interaction;
The Binding page: representing the predicted binding sites.
The Network page: representing the interaction sub-network of interacting ncRNA/Interactor.
- Detail
- Binding
- Network
Detail: | |
Vhid: | HHID00011225 |
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Virus: | Hepatitis C virus(HCV) |
Host Species: | Mus musculus |
ncRNA Source: | Host |
ncRNA Category: | miRNA |
ncRNA Symbol: | mmu-mir-29a |
Tissue: | tissue samples (104 HCC, 90 adjacent cirrhotic livers, 21 normal livers) as well as in 35 HCC cell lines |
Expression Direction of ncRNA: | - |
Interactor in Virus or Host: | Host |
Interactor Category: | Protein |
Interactor Symbol: | Bcl2 |
Expression Direction of Interactor: | - |
Validated Method: | Microarray and Computational Analysis,Quantitative PCR and Western Blot Analysis,premiRs and antagomiRs Transfection,Analysis of Putative miR-221 Targets. |
PMID: | 23108868 |
Detailed Description: | Two proapoptotic members, Bmf and Bim, are targeted by miR-221 and miR-15, respectively. Three antiapoptotic members, Bcl-2, Mcl-1 and Bcl-w are targets of miR-29, miR-101 and miR-122, respectively. |
The 'First Node' or 'Second Node' option represents the sub-network of interacting ncRNA/Interactor with the first or second interaction node,
the 'Both the Nodes' option represents the sub-network of interacting ncRNA/Interactor with both of interaction nodes.
The 'First Neighbour' represents the sub-network of direct interacting with the center node,
the 'Second Neighbour' represents the sub-network of direct or second step interacting with the center node.
Interaction sub-network based on the two nodes of this interaction may help the researchers represents all interacting partners immediately.