The Detail page: representing the detail information for virus-host related ncRNA interaction;
The Binding page: representing the predicted binding sites.
The Network page: representing the interaction sub-network of interacting ncRNA/Interactor.
- Detail
- Binding
- Network
Detail: | |
Vhid: | HHID00011188 |
---|---|
Virus: | Hepatitis C virus(HCV) |
Host Species: | Homo sapiens |
ncRNA Source: | Host |
ncRNA Category: | miRNA |
ncRNA Symbol: | hsa-mir-152 |
Tissue: | - |
Expression Direction of ncRNA: | Downregulation |
Interactor in Virus or Host: | Host |
Interactor Category: | Protein |
Interactor Symbol: | DNMT1 |
Expression Direction of Interactor: | Upregulation |
Validated Method: | Western Blot Analysis, luciferase Reporter assay, Northern Blotting. |
PMID: | 23108868 |
Detailed Description: | Upregulationof DNMT1 as a result of miR-152 downregulation has been observed during HCC development. miR-152 may participate in HBV-induced epigenetic modifications through DNMT1. |
The 'First Node' or 'Second Node' option represents the sub-network of interacting ncRNA/Interactor with the first or second interaction node,
the 'Both the Nodes' option represents the sub-network of interacting ncRNA/Interactor with both of interaction nodes.
The 'First Neighbour' represents the sub-network of direct interacting with the center node,
the 'Second Neighbour' represents the sub-network of direct or second step interacting with the center node.
Interaction sub-network based on the two nodes of this interaction may help the researchers represents all interacting partners immediately.