The Detail page: representing the detail information for virus-host related ncRNA interaction;
The Binding page: representing the predicted binding sites.
The Network page: representing the interaction sub-network of interacting ncRNA/Interactor.
- Detail
- Binding
- Network
| Detail: | |
| Vhid: | HHID00011170 |
|---|---|
| Virus: | Hepatitis C virus(HCV) |
| Host Species: | Homo sapiens |
| ncRNA Source: | Host |
| ncRNA Category: | miRNA |
| ncRNA Symbol: | hsa-mir-1-1 |
| Tissue: | - |
| Expression Direction of ncRNA: | Upregulation |
| Interactor in Virus or Host: | Host |
| Interactor Category: | Protein |
| Interactor Symbol: | FOXP1 |
| Expression Direction of Interactor: | Downregulation |
| Validated Method: | Western Blot Analysis, luciferase Reporter assay. |
| PMID: | 23108868 |
| Detailed Description: | Therapeutic intervention with hypomethylating agents could inhibit HCC cell growth by increasing miR-1-1 expression to inhibit expression of its two downstream oncogenes, MET(MNNG HOS transforming gene) and FoxP1(Forkhead box protein P1). |
The 'First Node' or 'Second Node' option represents the sub-network of interacting ncRNA/Interactor with the first or second interaction node,
the 'Both the Nodes' option represents the sub-network of interacting ncRNA/Interactor with both of interaction nodes.
The 'First Neighbour' represents the sub-network of direct interacting with the center node,
the 'Second Neighbour' represents the sub-network of direct or second step interacting with the center node.
Interaction sub-network based on the two nodes of this interaction may help the researchers represents all interacting partners immediately.