The Detail page: representing the detail information for virus-host related ncRNA interaction;
The Binding page: representing the predicted binding sites.
The Network page: representing the interaction sub-network of interacting ncRNA/Interactor.
- Detail
- Binding
- Network
| Detail: | |
| Vhid: | HHID00011101 |
|---|---|
| Virus: | Hepatitis B virus(HBV) |
| Host Species: | Homo sapiens |
| ncRNA Source: | Host |
| ncRNA Category: | miRNA |
| ncRNA Symbol: | hsa-miR-199a-3p |
| Tissue: | liver |
| Expression Direction of ncRNA: | Downregulation |
| Interactor in Virus or Host: | Host |
| Interactor Category: | Protein |
| Interactor Symbol: | CD44 |
| Expression Direction of Interactor: | - |
| Validated Method: | - |
| PMID: | 23108868 |
| Detailed Description: | To date, 132 miRNAs(out of 1527 identified in the human genome) have been linked to HCC(Table 1). Some of them are of clinical significance, and are valuable in diagnosing or predicting the prognosis of HCC. These miRNAs could be major factors and used for identification and classification of liver cancer. Chronic hepatitis B virus(HBV) and/or hepatitis C virus(HCV) infections resulting in hepatic fibrosis and cirrhosis are the major risk factors for HCC.Table 1 Deregulated miRNAs in HCC. |
The 'First Node' or 'Second Node' option represents the sub-network of interacting ncRNA/Interactor with the first or second interaction node,
the 'Both the Nodes' option represents the sub-network of interacting ncRNA/Interactor with both of interaction nodes.
The 'First Neighbour' represents the sub-network of direct interacting with the center node,
the 'Second Neighbour' represents the sub-network of direct or second step interacting with the center node.
Interaction sub-network based on the two nodes of this interaction may help the researchers represents all interacting partners immediately.