The Detail page: representing the detail information for virus-host related ncRNA interaction;
The Binding page: representing the predicted binding sites.
The Network page: representing the interaction sub-network of interacting ncRNA/Interactor.
- Detail
- Binding
- Network
Detail: | |
Vhid: | HHID00011041 |
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Virus: | Coxsackievirus B3(CVB3) |
Host Species: | Mus musculus |
ncRNA Source: | Host |
ncRNA Category: | miRNA |
ncRNA Symbol: | mmu-mir-203 |
Tissue: | Hearts |
Expression Direction of ncRNA: | Upregulation |
Interactor in Virus or Host: | Host |
Interactor Category: | Protein |
Interactor Symbol: | Zfp148 |
Expression Direction of Interactor: | Downregulation |
Validated Method: | Western blot analysis, Construction of luciferase reporter plasmids and its mutants, Quantitative real-time RT-PCR, Cell culture transfection, H&E staining and echocardiography, Luciferase reporter analysis, Viral plaque assay, Live-cell confocal imaging, Statistical analysis, Cell viability assay, MicroRNA microarray. |
PMID: | 22842794 |
Detailed Description: | MicroRNA-203 enhances coxsackievirus B3 replication through targeting zinc finger protein-148. We further identified zinc finger protein-148(ZFP-148), a transcription factor, as a novel target of miR-203. |
The 'First Node' or 'Second Node' option represents the sub-network of interacting ncRNA/Interactor with the first or second interaction node,
the 'Both the Nodes' option represents the sub-network of interacting ncRNA/Interactor with both of interaction nodes.
The 'First Neighbour' represents the sub-network of direct interacting with the center node,
the 'Second Neighbour' represents the sub-network of direct or second step interacting with the center node.
Interaction sub-network based on the two nodes of this interaction may help the researchers represents all interacting partners immediately.