• Detail
  • Binding
  • Network
Detail:
Vhid: HHID00011041
Virus: Coxsackievirus B3(CVB3)
Host Species: Mus musculus
ncRNA Source: Host
ncRNA Category: miRNA
ncRNA Symbol: mmu-mir-203
Tissue: Hearts
Expression Direction of ncRNA: Upregulation
Interactor in Virus or Host: Host
Interactor Category: Protein
Interactor Symbol: Zfp148
Expression Direction of Interactor: Downregulation
Validated Method: Western blot analysis, Construction of luciferase reporter plasmids and its mutants, Quantitative real-time RT-PCR, Cell culture transfection, H&E staining and echocardiography, Luciferase reporter analysis, Viral plaque assay, Live-cell confocal imaging, Statistical analysis, Cell viability assay, MicroRNA microarray.
PMID: 22842794
Detailed Description: MicroRNA-203 enhances coxsackievirus B3 replication through targeting zinc finger protein-148. We further identified zinc finger protein-148(ZFP-148), a transcription factor, as a novel target of miR-203.
Select the transcript of gene Zfp148 interacted with mmu-mir-203
The ncRNA Symbol: mmu-mir-203 Transcript of Zfp148:
Visualization:
Select the center nodes: First Node Second Node Both the Nodes
Select the Level of Neighbour: First Neighbour Second Neighbour
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The 'First Node' or 'Second Node' option represents the sub-network of interacting ncRNA/Interactor with the first or second interaction node, the 'Both the Nodes' option represents the sub-network of interacting ncRNA/Interactor with both of interaction nodes.
The 'First Neighbour' represents the sub-network of direct interacting with the center node, the 'Second Neighbour' represents the sub-network of direct or second step interacting with the center node. Interaction sub-network based on the two nodes of this interaction may help the researchers represents all interacting partners immediately.

The Detail page: representing the detail information for virus-host related ncRNA interaction;
The Binding page: representing the predicted binding sites.
The Network page: representing the interaction sub-network of interacting ncRNA/Interactor.