The Detail page: representing the detail information for virus-host related ncRNA interaction;
The Binding page: representing the predicted binding sites.
The Network page: representing the interaction sub-network of interacting ncRNA/Interactor.
- Detail
- Binding
- Network
| Detail: | |
| Vhid: | VVID00011013 |
|---|---|
| Virus: | Rhesus lymphocryptovirus(rLCV) |
| Host Species: | Macaca mulatta |
| ncRNA Source: | Virus |
| ncRNA Category: | miRNA |
| ncRNA Symbol: | rlcv-miR-rL1-6-3p |
| Tissue: | rLCV-infected rhesus macaquerLCLs |
| Expression Direction of ncRNA: | - |
| Interactor in Virus or Host: | Virus |
| Interactor Category: | Protein |
| Interactor Symbol: | BHRF1 |
| Expression Direction of Interactor: | Downregulation |
| Validated Method: | Western blot analysis, PAR-CLIP, qRT-PCR for RISC-associated BHRF1 mRNAs,Luciferase reporter assays. |
| PMID: | 24257599 |
| Detailed Description: | In addition to miR-BART10, we observed significant inhibition of the EBV BHRF1 3'UTR reporter in the presence of miR-BART1. miR-BART1-3p and its rLCV homolog, miR-rL1-6-3p, have seed matches (nt 2 to 8) to the EBV and rLCV BHRF1 3'UTRs, al-though the positions of the seed match sites and the miRNA inhibition are not conserved. . |
The 'First Node' or 'Second Node' option represents the sub-network of interacting ncRNA/Interactor with the first or second interaction node,
the 'Both the Nodes' option represents the sub-network of interacting ncRNA/Interactor with both of interaction nodes.
The 'First Neighbour' represents the sub-network of direct interacting with the center node,
the 'Second Neighbour' represents the sub-network of direct or second step interacting with the center node.
Interaction sub-network based on the two nodes of this interaction may help the researchers represents all interacting partners immediately.