The Detail page: representing the detail information for virus-host related ncRNA interaction;
The Binding page: representing the predicted binding sites.
The Network page: representing the interaction sub-network of interacting ncRNA/Interactor.
- Detail
- Binding
- Network
Detail: | |
Vhid: | VVID00010969 |
---|---|
Virus: | Human immunodeficiency virus 1(HIV-1) |
Host Species: | Homo sapiens |
ncRNA Source: | Virus |
ncRNA Category: | miRNA |
ncRNA Symbol: | hiv1-mir-TAR |
Tissue: | - |
Expression Direction of ncRNA: | - |
Interactor in Virus or Host: | Virus |
Interactor Category: | Protein |
Interactor Symbol: | tat |
Expression Direction of Interactor: | - |
Validated Method: | Dual-label competition filter binding assay. |
PMID: | 8450553 |
Detailed Description: | The binding site for tat protein on TAR RNA has been defined in quantitative terms using an extensive series of mutations. The relative dissociation constants for the mutant TAR RNAs were measured using a dual-label competition filter binding assay in which 35S-labelled wild-type TAR RNA(K1) was competed against 3H-labelled mutant TAR RNA(K2). |
The 'First Node' or 'Second Node' option represents the sub-network of interacting ncRNA/Interactor with the first or second interaction node,
the 'Both the Nodes' option represents the sub-network of interacting ncRNA/Interactor with both of interaction nodes.
The 'First Neighbour' represents the sub-network of direct interacting with the center node,
the 'Second Neighbour' represents the sub-network of direct or second step interacting with the center node.
Interaction sub-network based on the two nodes of this interaction may help the researchers represents all interacting partners immediately.