• Detail
  • Binding
  • Network
Detail:
Vhid: VVID00010926
Virus: Herpes simplex virus 1(HSV-1)
Host Species: Homo sapiens
ncRNA Source: Virus
ncRNA Category: miRNA
ncRNA Symbol: hsv1-mir-H4
Tissue: neurons
Expression Direction of ncRNA: -
Interactor in Virus or Host: Virus
Interactor Category: mRNA
Interactor Symbol: ICP34.5
Expression Direction of Interactor: Downregulation
Validated Method: Predicted.
PMID: 19158788
Detailed Description: In addition to miR-H2-3p lying antisense to ICP0, HSV-1 miR-H3 and miR-H4 also lie antisense to the gene encoding the pathogenicity factor ICP34.5 and, based on genetic data, were proposed to inhibit ICP34.5 expression in latently infected neurons.
Visualization:
Select the center nodes: First Node Second Node Both the Nodes
Select the Level of Neighbour: First Neighbour Second Neighbour
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The 'First Node' or 'Second Node' option represents the sub-network of interacting ncRNA/Interactor with the first or second interaction node, the 'Both the Nodes' option represents the sub-network of interacting ncRNA/Interactor with both of interaction nodes.
The 'First Neighbour' represents the sub-network of direct interacting with the center node, the 'Second Neighbour' represents the sub-network of direct or second step interacting with the center node. Interaction sub-network based on the two nodes of this interaction may help the researchers represents all interacting partners immediately.

The Detail page: representing the detail information for virus-host related ncRNA interaction;
The Network page: representing the interaction sub-network of interacting ncRNA/Interactor.